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ChemicalBook >> CAS DataBase List >>5,4'-DIHYDROXYFLAVONE

5,4'-DIHYDROXYFLAVONE

5,4'-DIHYDROXYFLAVONE Structure
5,4'-DIHYDROXYFLAVONE structure
CAS No.
6665-67-4
Chemical Name:
5,4'-DIHYDROXYFLAVONE
Synonyms
5-Dihydroxyflavone;4',5-Dihydroxyflavone;5,4'-DIHYDROXYFLAVONE;5-Hydroxy-2-(4-hydroxyphenyl);4'',5-Dihydroxyflavone, 10 mM in DMSO;5-Hydroxy-2-(4-hydroxyphenyl)-4H-chroMen-4-one;4H-1-Benzopyran-4-one, 5-hydroxy-2-(4-hydroxyphenyl)-;Lipoxygenase,Glucosidase,LOX,4',5-Dihydroxyflavone,4',5 Dihydroxyflavone,inhibit,Inhibitor,4',5Dihydroxyflavone
CBNumber:
CB6234481
Molecular Formula:
C15H10O4
Molecular Weight:
254.24
MDL Number:
MFCD00017691
MOL File:
6665-67-4.mol
MSDS File:
SDS
Last updated:2025-04-18 09:51:20
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5,4'-DIHYDROXYFLAVONE Properties

Melting point 239-240°C
Boiling point 486.0±45.0 °C(Predicted)
Density 1.443±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : ≥ 155 mg/mL (609.66 mM);Water : < 0.1 mg/mL (insoluble)
pka 6.78±0.40(Predicted)
form Solid
color Light yellow to yellow

SAFETY

Risk and Safety Statements

NFPA 704
1
0 0

5,4'-DIHYDROXYFLAVONE price More Price(16)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Alfa Aesar H27650 4',5-Dihydroxyflavone, 95% 6665-67-4 1g $54.2 2021-12-16 Buy
Alfa Aesar H27650 4',5-Dihydroxyflavone, 95% 6665-67-4 5g $161 2021-12-16 Buy
Alfa Aesar H27650 4',5-Dihydroxyflavone, 95% 6665-67-4 25g $483 2021-12-16 Buy
TRC D679110 4'',5-Dihydroxyflavone 6665-67-4 1g $240 2021-12-16 Buy
Biosynth Carbosynth FD66316 4',5-Dihydroxyflavone 6665-67-4 2g $184 2021-12-16 Buy
Product number Packaging Price Buy
H27650 1g $54.2 Buy
H27650 5g $161 Buy
H27650 25g $483 Buy
D679110 1g $240 Buy
FD66316 2g $184 Buy

5,4'-DIHYDROXYFLAVONE Chemical Properties,Uses,Production

Uses

4',5-Dihydroxyflavone is a soybean LOX-1 and yeast α-Glucosidase inhibitor, with an Ki of 102.6 μM for soybean LOX-1 and an IC50 of 66 μM for yeast α-glucosidase. LOX-1 isshort for Lectin-like oxidized low-density lipoprotein receptor-1.

References

[1] Ribeiro D, et al. Inhibition of LOX by flavonoids: a structure-activity relationship study. Eur J Med Chem. 2014 Jan 24;72:137-45. DOI:10.1016/j.ejmech.2013.11.030
[2] Proen?a C, et al. α-Glucosidase inhibition by flavonoids: an in vitro and in silico structure-activity relationship study. J Enzyme Inhib Med Chem. 2017 Dec;32(1):1216-1228. DOI:10.1080/14756366.2017.1368503

5,4'-DIHYDROXYFLAVONE Preparation Products And Raw materials

Raw materials

Preparation Products

5,4'-DIHYDROXYFLAVONE Suppliers

Global( 83)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
Hubei xin bonus chemical co. LTD 		86-13657291602 linda@hubeijusheng.com CHINA 22963 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32159 58
Career Henan Chemica Co 		+86-0371-86658258 +8613203830695 laboratory@coreychem.com China 30231 58
sgtlifesciences pvt ltd 		+8617013299288 dj@sgtlifesciences.com China 12373 58
InvivoChem 		+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6391 58
TargetMol Chemicals Inc. 		support@targetmol.com United States 38630 58
Aladdin Scientific 		tp@aladdinsci.com United States 57505 58
XIAMEN AMITY INDUSTRY AND TRADE CO., LTD. 		+8618950047208 ellena@amitychem.com China 43416 58
DAYANG CHEM (HANGZHOU) CO.,LTD 		+8617705817739 info@dycnchem.com China 53881 58
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 		60
Hubei xin bonus chemical co. LTD 		58
TargetMol Chemicals Inc. 		58
Career Henan Chemica Co 		58
sgtlifesciences pvt ltd 		58
InvivoChem 		58
TargetMol Chemicals Inc. 		58
Aladdin Scientific 		58
XIAMEN AMITY INDUSTRY AND TRADE CO., LTD. 		58
DAYANG CHEM (HANGZHOU) CO.,LTD 		58

View Lastest Price from 5,4'-DIHYDROXYFLAVONE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4',5-Dihydroxyflavone pictures 2024-11-19 4',5-Dihydroxyflavone
6665-67-4
 US $34.00-113.00 / mg 95.38% 10g TargetMol Chemicals Inc.

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5,4'-DIHYDROXYFLAVONE 5-Hydroxy-2-(4-hydroxyphenyl)-4H-chroMen-4-one 5-Hydroxy-2-(4-hydroxyphenyl) 4H-1-Benzopyran-4-one, 5-hydroxy-2-(4-hydroxyphenyl)- 5-Dihydroxyflavone Lipoxygenase,Glucosidase,LOX,4',5-Dihydroxyflavone,4',5 Dihydroxyflavone,inhibit,Inhibitor,4',5Dihydroxyflavone 4',5-Dihydroxyflavone 4'',5-Dihydroxyflavone, 10 mM in DMSO 6665-67-4 Di-substituted Flavones