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Deoxyphorbol

CAS No.
37415-57-9
Chemical Name:
Deoxyphorbol
Synonyms
Deoxyphorbol;4-deoxy-4-Phorbol;4-deoxy-4α-Phorbol;(1aR)-1,1aα,1bβ,4,4aα,7aα,7b,8,9,9a-Decahydro-7bα,9β,9aα-trihydroxy-3-hydroxymethyl-1,1,6,8α-tetramethyl-5H-cyclopropa[3,4]benz[1,2-e]azulen-5-one;(1aR)-1,1,6,8α-Tetramethyl-3-(hydroxymethyl)-7bα,9β,9aα-trihydroxy-1,1aα,1bβ,4,4aα,7aα,7b,8,9,9a-decahydro-5H-cyclopropa[3,4]benzo[1,2-e]azulene-5-one;5H-Cyclopropa[3,4]benz[1,2-e]azulen-5-one, 1,1a,1b,4,4a,7a,7b,8,9,9a-decahydro-7b,9,9a-trihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-, (1aR,1bS,4aR,7aR,7bR,8R,9R,9aS)-
CBNumber:
CB62363967
Molecular Formula:
C20H28O5
Molecular Weight:
348.43
MDL Number:
MOL File:
37415-57-9.mol
Last updated:2024-07-02 08:55:13

Deoxyphorbol Properties

Boiling point 531.9±50.0 °C(Predicted)
Density 1.311±0.06 g/cm3(Predicted)
solubility DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: slightly soluble; PBS (pH 7.2): 1 mg/ml
form A crystalline solid
pka 13.70±0.70(Predicted)
color White to off-white

Deoxyphorbol price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 24998 4-deoxy-4α-Phorbol ≥98% 37415-57-9 1mg $49 2024-03-01 Buy
Cayman Chemical 24998 4-deoxy-4α-Phorbol ≥98% 37415-57-9 5mg $156 2024-03-01 Buy
Cayman Chemical 24998 4-deoxy-4α-Phorbol ≥98% 37415-57-9 10mg $263 2024-03-01 Buy
Cayman Chemical 24998 4-deoxy-4α-Phorbol ≥98% 37415-57-9 25mg $593 2024-03-01 Buy
Product number Packaging Price Buy
24998 1mg $49 Buy
24998 5mg $156 Buy
24998 10mg $263 Buy
24998 25mg $593 Buy

Deoxyphorbol Chemical Properties,Uses,Production

Description

4-deoxy-4α-Phorbol is a tetracyclic diterpene found in croton oil.1,2 It has been used in the semisynthesis of inhibitors of the HIV-1-induced cytopathic effect on MT-4 cells and 4α-phorbol esters.

References

1. El-Mekkawy, S., Meselhy, M.R., Abdel-Hafez, A.A., et al. Inhibition of cytopathic effect of human immunodeficiency virus type-1 by various phorbol derivatives Chem. Pharm. Bull. (Tokyo) 50(4),523-529(2002).
2. Klausen, T.K., Pagani, A., Minassi, A., et al. Modulation of the transient receptor potential vanilloid channel TRPV4 by 4α-phorbol esters: A structure-activity study J. Med. Chem. 52(9),2933-2939(2009).

Deoxyphorbol Preparation Products And Raw materials

Raw materials

Preparation Products

Deoxyphorbol Suppliers

Global( 10)Suppliers
Supplier Tel Email Country ProdList Advantage
Chengdu Biopurify Phytochemicals Ltd.
+8618080483897 sales@biopurify.com China 3772 58
Mensura Group Limited
+8618109034517 hkd008@vacorda.com China 2900 58
Chengdu Biopurify Phytochemicals Ltd. +86-028-82633397 18982077548 cwb1@biopurify.cn China 2376 60
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6777 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11217 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24647 58
Naturewill Biotechnology Co., Ltd. 18113192475 18113192475 3157321941@qq.com China 5001 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11974 58
Mensura Group Limited 18109034517 18109034517@163.com China 2898 58
(1aR)-1,1,6,8α-Tetramethyl-3-(hydroxymethyl)-7bα,9β,9aα-trihydroxy-1,1aα,1bβ,4,4aα,7aα,7b,8,9,9a-decahydro-5H-cyclopropa[3,4]benzo[1,2-e]azulene-5-one (1aR)-1,1aα,1bβ,4,4aα,7aα,7b,8,9,9a-Decahydro-7bα,9β,9aα-trihydroxy-3-hydroxymethyl-1,1,6,8α-tetramethyl-5H-cyclopropa[3,4]benz[1,2-e]azulen-5-one Deoxyphorbol 4-deoxy-4-Phorbol 4-deoxy-4α-Phorbol 5H-Cyclopropa[3,4]benz[1,2-e]azulen-5-one, 1,1a,1b,4,4a,7a,7b,8,9,9a-decahydro-7b,9,9a-trihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-, (1aR,1bS,4aR,7aR,7bR,8R,9R,9aS)- 37415-57-9