ISOMENTHONE
- CAS No.
- 36977-92-1
- Chemical Name:
- ISOMENTHONE
- Synonyms
- FEMA 3460;ISO-METHON;ISOMENTHONE;ISOMENTHONE P;Isomenthoneextra;ISOMENTHONE USP/EP/BP;ISOMENTHONE TECHNICAL GRADE;(±)-cis-5-Methyl-2-(1-methylethyl)cyclohexanone
- CBNumber:
- CB6242091
- Molecular Formula:
- C10H18O
- Molecular Weight:
- 154.25
- MDL Number:
- MFCD00136032
- MOL File:
- 36977-92-1.mol
- MSDS File:
- SDS
| FEMA | 3460 | D,L-ISOMENTHONE |
|---|---|
| color | A colourless slightly oily liquid |
| Odor | The powerful, refreshing and clean-minty odour of moderate tenacity. Somewhat cooling mouthfeel and a refreshing, minty, but distinctly bitter taste. |
| Water Solubility | Almost insoluble in water, soluble in alcohol, Propylene glycol, mineral oil and perfume and flavour materials. Very poorly soluble in Glycerin. |
| EWG's Food Scores | 1 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H317 |
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P261-P272-P280-P302+P352-P333+P313-P321-P363-P501 |
| Toxicity | The acute dermal LD 5 0 in rabbits was reported as > 5 ml/kg (Levenstein, 1973). |
ISOMENTHONE Chemical Properties,Uses,Production
Occurrence
d-Isomenthone has been reported to have been isolated from Micromeria abissinica Benth., Pelargonium tomentosum Jacquin and others. /-Isomenthone has been identified in Reunion geranium, Pelargonium capitatum and others (FenaroWs Handbook of Flavor Ingredients, 1971).
Uses
Isomenthone has very interesting effects in Rose, Carnation, Muguet, Fougeres, Lavender-complexes, etc. The use concentration will normally be about 0.5 to 200, but it may be somewhat higher in Rose and Lavender. The spicy notes in certain types of Men’s fragrances can eliminate the unpleasant sweetness brought about by the conventional Spice and Fougere fixatives.
Preparation
By hydrogénation of piperitone.
Definition
ChEBI: (-)-isomenthone is an isomenthone. It is an enantiomer of a (+)-isomenthone.
Production Methods
Isomenthone is produced 1) by isolation from Moroccan enny royal oil (dextro-Menthone). 2) by isolation from Congo Geranium oil (laevo-Menthone). 3) synthetic from 3-Methylcyclohexanone via its Glyoxylester and the corresponding Ketal to iso-Pulegone. This ketone is then treated with alcoholic Sodiumethylate to yield dl-pulegone, which is hydrogenated to iso-Menthone (dl-iso-Menthone).
Metabolism
d-Isomenthone undergoes reduction in the rabbit, since d-isomethylglucuronide is excreted in the urine. The other possible reduction product, d-neoisomenthol is not excreted (Williams, 1959).
ISOMENTHONE Preparation Products And Raw materials
Raw materials
Preparation Products
ISOMENTHONE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | 1026@dideu.com | China | 9030 | 58 |
| BeiJing TOP Science Bio-Technology Co., Ltd. | +86-13439059536 +86-15201677815 | China | 291 | 58 |
| Supplier | Advantage |
|---|---|
| Shaanxi Dideu Medichem Co. Ltd | 58 |
| BeiJing TOP Science Bio-Technology Co., Ltd. | 58 |
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