Teicoplanin A3-1
- CAS No.
- 93616-27-4
- Chemical Name:
- Teicoplanin A3-1
- Synonyms
- L 17054;Teicoplanin A3-1;Teicoplanin A3-1 DISCONTINUED. Please see T015500;34-O-[2-(acetylamino)-2-deoxy-β-D-glucopyranosyl]-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-42-O-α-D-mannopyranosyl-ristomycinAaglycone;Ristomycin A aglycone, 34-O-[2-(acetylamino)-2-deoxy-β-D-glucopyranosyl]-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-42-O-α-D-mannopyranosyl-
- CBNumber:
- CB62436968
- Molecular Formula:
- C72H68Cl2N8O28
- Molecular Weight:
- 1564.25
- MDL Number:
- MFCD33021344
- MOL File:
- 93616-27-4.mol
- MSDS File:
- SDS
| Density | 1.80±0.1 g/cm3(Predicted) |
|---|---|
| storage temp. | Store at -20°C |
| solubility | Soluble in ethanol;Soluble in methanol;Soluble in DMSO;Soluble in dimethyl formamide |
| form | solid |
| pka | 2.88±0.40(Predicted) |
| FDA UNII | SR8H9JSC9D |
Teicoplanin A3-1 price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 20193 | Teicoplanin A3-1 ≥98% | 93616-27-4 | 1mg | $242 | 2024-03-01 | Buy |
| Cayman Chemical | 20193 | Teicoplanin A3-1 ≥98% | 93616-27-4 | 5mg | $846 | 2024-03-01 | Buy |
| ApexBio Technology | C4943 | TeicoplaninA3-1 | 93616-27-4 | 5mg | $966 | 2021-12-16 | Buy |
| ApexBio Technology | C4943 | TeicoplaninA3-1 | 93616-27-4 | 1mg | $276 | 2021-12-16 | Buy |
| AK Scientific | 2702CW | TeicoplaninA3-1 | 93616-27-4 | 1mg | $368 | 2021-12-16 | Buy |
Teicoplanin A3-1 Chemical Properties,Uses,Production
Uses
Teicoplanin A3-1 is an antibiotic against Gram positive bacteria.
Uses
Teicoplanin A3-1 is a minor polar analogue of a family of lipoglycopeptides produced by Actinoplanes teichomyceticus. Teicoplanins possess potent broad spectrum antibiotic activity against Gram positive bacteria, including MRSA and E. faecalis. Teicoplanin A3-1 is the common degradation product of teicoplanins A2-1 to 5, resulting from cleavage of the lipoaminoglycoside substituents.
Definition
ChEBI: A glycopeptide consisting of a macropolycyclic heptapeptide in which a phenolic hydroxy group has been converted to its alpha-D-mannoside while a secondary alcohol group has been converted to the corresponding 2-acetamido- -deoxy-beta-D-glucoside.
Biological Activity
teicoplanin a3-1, also known as antibiotic l 17054, is a glycopeptide antibiotic derived from actinoplanes teichomyceticus and produces a potent broad spectrum antibiotic activity against gram-positive bacteria.teicoplanin a3-1 is a common degradation product of teicoplanins a2-1 to 5, which results from cleavage of the lipoaminoglycoside substituents. teicoplanins are glycopeptide antibiotics produced by a. teichomyceticus which are effective against gram-positive bacteria, including methicillin-resistant staphylococcus aureus (mrsa) and e. faecalis. as an antibiotic complex, teicoplanin consists of five closely related factors, t-a2-1, 2, 3, 4 and 5 and a more polar factor, t-a3-1. additionally, as a glycopeptide antibiotic belonging to the same family as vancomycin, teicoplanin blocks cell wall synthesis in bacillus subtilis, which is accompanied by an intracellular accumulation of udp-n-acetylmuramyl-pentapetide [1]. due to the greater antibacterial activity of teicoplanin than other agents, it has been thoroughly studied as a β-1actamase-resistant agent for the treatment of human infections caused by streptococci and staphylococci, including enterococci [2].
References
[1]. somma, s., gastaldo, l., & corti, a. teicoplanin, a new antibiotic from actinoplanes teichomyceticus nov. sp. antimicrobial agents and chemotherapy. 1984; 26(6): 917-923.
[2]. traina, g., & bonati, m. pharmacokinetics of teicoplanin in man after intravenous administration. journal of pharmacokinetics and biopharmaceutics. 1984;12(2): 119-128.
Teicoplanin A3-1 Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| ChemStrong Scientific Co.,Ltd | 0755-0755-66853366 13670046396 | sales@chem-strong.com | China | 18042 | 56 |
| BOC Sciences | 16314854226 | info@bocsci.com | United States | 9923 | 65 |
| Lynnchem | 86-(0)29-85992781 17792393971 | info@lynnchem.com | China | 4587 | 58 |
| Novachemistry | 44-20819178-90 02081917890 | info@novachemistry.com | United Kingdom | 4381 | 58 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 +86-13028896684; | sales@rrkchem.com | China | 57412 | 58 |
| Meng Cheng Technology (Shanghai) Co., LTD | 400-820-6829 | sales@mitachieve.com | China | 8860 | 58 |
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 | order@med-bio.cn | China | 8140 | 58 |
| Foshan Treasure Biotechnology Co., Ltd | 0757-85921206 18520245316 | 2329783215@qq.com | China | 12661 | 58 |