3-Cyano-4-methylphenylboronic acid, pinacol ester
- CAS No.
- 1220219-11-3
- Chemical Name:
- 3-Cyano-4-methylphenylboronic acid, pinacol ester
- Synonyms
- 3-Cyano-4-methylphenylboronic acid, pinacol ester;2-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile;Benzonitrile, 2-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
- CBNumber:
- CB62513263
- Molecular Formula:
- C14H18BNO2
- Molecular Weight:
- 243.11
- MDL Number:
- MFCD18087706
- MOL File:
- 1220219-11-3.mol
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H312-H315-H319-H332-H335 |
| Precautionary statements | P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501 |
| HS Code | 2931900090 |
3-Cyano-4-methylphenylboronic acid, pinacol ester price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | C987683 | 3-Cyano-4-methylphenylboronicacid,pinacolester | 1220219-11-3 | 500mg | $205 | 2021-12-16 | Buy |
| AK Scientific | Z8579 | 3-Cyano-4-methylphenylboronicacidpinacolester | 1220219-11-3 | 1g | $237 | 2021-12-16 | Buy |
| Crysdot | CD12171274 | 2-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile 95+% | 1220219-11-3 | 5g | $489 | 2021-12-16 | Buy |
| AOBChem | 26217 | 3-Cyano-4-methylphenylboronicacid,pinacolester 97% | 1220219-11-3 | 10g | $840 | 2021-12-16 | Buy |
| AOBChem | 26217 | 3-Cyano-4-methylphenylboronicacid,pinacolester 97% | 1220219-11-3 | 25g | $1650 | 2021-12-16 | Buy |
3-Cyano-4-methylphenylboronic acid, pinacol ester Chemical Properties,Uses,Production
Chemical Properties
3-Cyano-4-methylphenylboronic acid, pinacol ester, also named as 2-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile, is a white solid.
Preparation
5-Bromo-2-methylbenzonitrile (40 g, 204 mmol), bis(pinacolato)diboron (69.2 g, 306 mmol), potassium acetate (60 g, 612 mmol), PdCl2(dppf) (7.6 g, 20.8 mmol) and 1,4-dioxane (500 mL) were added in a 1 L single-neck flask, and the reaction mixture was heated to react at 100 ℃ for 2 hours.
After completion of the reaction, the mixture was cooled to room temperature, then water (250 mL) was added.
The mixture was extracted with ethyl acetate (3?250 mL), and the organic layers were concentrated in vacuo to remove the solvent.
The residue was separated by a silica gel column (petroleum ether: ethyl acetate = 30:1) to give 3-Cyano-4-methylphenylboronic acid, pinacol ester.
3-Cyano-4-methylphenylboronic acid, pinacol ester Preparation Products And Raw materials
Raw materials
Preparation Products
3-Cyano-4-methylphenylboronic acid, pinacol ester Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Shanghai Gubang New Materail Technology Co. LTD | 21-51317962 +8618721305404 | 16728589@qq.com | CHINA | 272 | 58 |
| Coresyn Pharmatech Co., Ltd. | +86-571-86626709 +86-18157142896 | cbc@coresyn.com | China | 9984 | 58 |
| 9ding chemical ( Shanghai) Limited | 4009209199 | sales@9dingchem.com | China | 18209 | 56 |
| Shanghai ShiXian Chemical Technology Co., Ltd. | 18681884732 18681884732 | 2245256225@qq.com | China | 1510 | 50 |
| ShangHai AmK Pharmaceutical Technology Co., Ltd. | 18019252918 | sale@amkchem.com | China | 15297 | 55 |
| Suzhou Chenke Biotech Co., Ltd. | 18662408853 18662408853 | 2120408911@qq.com | China | 898 | 55 |
| Shanghai Pingguo Pharmaceutical Co., Ltd. | 021-20432229 | 2412110556@qq.com | China | 6017 | 55 |
| AAB-PHARMA LIMITED | 025-66800956 18800000000 | sales@njdmchem.com | China | 4200 | 50 |
| Aikon International Limited | 025-66113011 18112977050 | cb6@aikonchem.com | China | 15494 | 58 |