ChemicalBook >> CAS DataBase List >>1H-Indole-2-carboxamide, N-[trans-4-[2-(7-cyano-3,4-dihydro-2(1H)-isoquinolinyl)ethyl]cyclohexyl]-
1H-Indole-2-carboxamide, N-[trans-4-[2-(7-cyano-3,4-dihydro-2(1H)-isoquinolinyl)ethyl]cyclohexyl]-
![1H-Indole-2-carboxamide, N-[trans-4-[2-(7-cyano-3,4-dihydro-2(1H)-isoquinolinyl)ethyl]cyclohexyl]- Structure](CAS2/GIF/215802-15-6.gif)
- CAS No.
- 215802-15-6
- Chemical Name:
- 1H-Indole-2-carboxamide, N-[trans-4-[2-(7-cyano-3,4-dihydro-2(1H)-isoquinolinyl)ethyl]cyclohexyl]-
- Synonyms
- SB269652;SB 269652; SB-269652;SB269652 >=98% (HPLC);1H-Indole-2-carboxamide, N-[trans-4-[2-(7-cyano-3,4-dihydro-2(1H)-isoquinolinyl)ethyl]cyclohexyl]-
- CBNumber:
- CB62518011
- Molecular Formula:
- C27H30N4O
- Molecular Weight:
- 426.5533
- MDL Number:
- MFCD18910624
- MOL File:
- 215802-15-6.mol
Last updated:2025-01-27 09:38:02
1H-Indole-2-carboxamide, N-[trans-4-[2-(7-cyano-3,4-dihydro-2(1H)-isoquinolinyl)ethyl]cyclohexyl]- Properties
| Boiling point | 690.6±55.0 °C(Predicted) |
|---|---|
| Density | 1.24±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | Soluble in DMSO |
| form | Powder |
| pka | 15.45±0.30(Predicted) |
| color | White to off-white |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
1H-Indole-2-carboxamide, N-[trans-4-[2-(7-cyano-3,4-dihydro-2(1H)-isoquinolinyl)ethyl]cyclohexyl]- price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Crysdot | CD31002667 | SB269652 98+% | 215802-15-6 | 5mg | $245 | 2021-12-16 | Buy |
| Crysdot | CD31002667 | SB269652 98+% | 215802-15-6 | 10mg | $350 | 2021-12-16 | Buy |
| Crysdot | CD31002667 | SB269652 98+% | 215802-15-6 | 50mg | $1050 | 2021-12-16 | Buy |
| Crysdot | CD31002667 | SB269652 98+% | 215802-15-6 | 100mg | $1470 | 2021-12-16 | Buy |
1H-Indole-2-carboxamide, N-[trans-4-[2-(7-cyano-3,4-dihydro-2(1H)-isoquinolinyl)ethyl]cyclohexyl]- Chemical Properties,Uses,Production
Biological Activity
SB269652 is an allosteric modulator of D2 dopamine receptors. SB269652 binds to an allosteric site th at is distinct from the orthosteric bound by typical D2 antagonists and is only revealed in D2 receptor dimers. SB269652 is bitopic, binding to an orthosteric site one one partner in the dimer and the allosteric site in the other. Engagement of this secondary pocket at the extracellular end of TM2 and TM7 is a new mechanism of modulating binding of a ligand to the orthosteric site of a second protomer by a G-protein coupled receptor.
1H-Indole-2-carboxamide, N-[trans-4-[2-(7-cyano-3,4-dihydro-2(1H)-isoquinolinyl)ethyl]cyclohexyl]- Preparation Products And Raw materials
Raw materials
Preparation Products
1H-Indole-2-carboxamide, N-[trans-4-[2-(7-cyano-3,4-dihydro-2(1H)-isoquinolinyl)ethyl]cyclohexyl]- Suppliers
Global( 19)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32161 | 58 |
| TargetMol Chemicals Inc. | +8613564774135 | zijue.cai@tsbiochem.com | United States | 19881 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| LETOPHARM LIMITED | +86-21-5821 5861 | sales@letopharm.com | China | 2384 | 58 |
| SPIRO PHARMA | eric_feng1954@126.com | China | 9248 | 55 | |
| BOC Sciences | 16314854226 | info@bocsci.com | United States | 9923 | 65 |
| Musechem | +1-800-259-7612 | info@musechem.com | United States | 4660 | 60 |
| Absin Bioscience Inc. | 021-38015121 15000105423 | wulan@absin.cn | China | 24731 | 58 |
| Shanghai Botuo Biotechnology Co., LTD | 16621358918 | botuopharma888@163.com | China | 9208 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44918 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |
| TargetMol Chemicals Inc. | 58 |
| Amadis Chemical Company Limited | 58 |
| LETOPHARM LIMITED | 58 |
| SPIRO PHARMA | 55 |
| BOC Sciences | 65 |
| Musechem | 60 |
| Absin Bioscience Inc. | 58 |
| Shanghai Botuo Biotechnology Co., LTD | 58 |
| Energy Chemical | 58 |
View Lastest Price from 1H-Indole-2-carboxamide, N-[trans-4-[2-(7-cyano-3,4-dihydro-2(1H)-isoquinolinyl)ethyl]cyclohexyl]- manufacturers
1H-Indole-2-carboxamide, N-[trans-4-[2-(7-cyano-3,4-dihydro-2(1H)-isoquinolinyl)ethyl]cyclohexyl]-
SB269652
SB 269652; SB-269652
SB269652 >=98% (HPLC)
215802-15-6