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(R)-5-bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine

CAS No.
877399-00-3
Chemical Name:
(R)-5-bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine
Synonyms
Crizotinib Impurity 3;5-bromo-3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]pyridin-2-amine;Crizotinib-H;Crizotinib intermediates 1;Chiral intermediate of crizotinib;chiral intermediates of Crizotinib;(R)-5-bromo-3-(1-(2,6-dichloro-3-fluorophenyl)etho;chiral intermediates of Crizotinib Company Standards;(R)-5-bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin...;(R)-5-broMo-3-[1-(2,6-dichloro-3-fluoropehnyl)ethoxy]pyridin-2-aMine
CBNumber:
CB62520755
Molecular Formula:
C13H10BrCl2FN2O
Molecular Weight:
380.04
MDL Number:
MFCD18207061
MOL File:
877399-00-3.mol
Last updated:2024-04-25 17:59:01

(R)-5-bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine Properties

Melting point 107.0 to 111.0 °C
Boiling point 423.4±40.0 °C(Predicted)
Density 1.643
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
form powder to crystal
pka 5.55±0.10(Predicted)
color White to Light yellow to Light orange
InChI InChI=1S/C13H10BrCl2FN2O/c1-6(11-8(15)2-3-9(17)12(11)16)20-10-4-7(14)5-19-13(10)18/h2-6H,1H3,(H2,18,19)/t6-/m1/s1
InChIKey URFUZAZEKBBCEY-ZCFIWIBFSA-N
SMILES C1(N)=NC=C(Br)C=C1O[C@@H](C1=C(Cl)C=CC(F)=C1Cl)C

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
HS Code  2933.39.9200
NFPA 704
0
2 0

(R)-5-bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine price More Price(19)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical B5682 (R)-5-Bromo-3-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]pyridin-2-amine >98.0%(HPLC) 877399-00-3 1g $94 2024-03-01 Buy
TCI Chemical B5682 (R)-5-Bromo-3-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]pyridin-2-amine >98.0%(HPLC) 877399-00-3 5g $375 2024-03-01 Buy
TRC B678833 (R)-5-Bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine 877399-00-3 500mg $55 2021-12-16 Buy
Chem-Impex 41654 (R)-5-Bromo-3-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]pyridin-2-amine,98%(HPLC) 98%(HPLC) 877399-00-3 1G $54.88 2021-12-16 Buy
Matrix Scientific 089899 (R)-5-Bromo-3-(1-(2,6-dichloro-3-fluorophenyl)-ethoxy)pyridin-2-amine 95+% 877399-00-3 250mg $394 2021-12-16 Buy
Product number Packaging Price Buy
B5682 1g $94 Buy
B5682 5g $375 Buy
B678833 500mg $55 Buy
41654 1G $54.88 Buy
089899 250mg $394 Buy

(R)-5-bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine Chemical Properties,Uses,Production

Chemical Properties

Pale yellow solid

Uses

(R)-5-Bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine is used in preparation of Crizotinib intermediate.

(R)-5-bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 270)Suppliers
Supplier Tel Email Country ProdList Advantage
Hefei TianRui Pharmaceutical Chemical Co., Ltd.
+86-0551-68665055 +86-+86-18616906106 sales@trywchem.com China 148 58
Zison Pharmaceutical (Shandong) Co., Ltd.
+86-0086-531-88259693 +86-18660188356 tracy.li@zisonpharm.com China 57 58
Jinan Million Pharmaceutical Co., Ltd
0531-68659554 +8613031714605 info@millionpharm.com China 252 58
Henan Fengda Chemical Co., Ltd
+86-371-86557731 +86-13613820652 info@fdachem.com China 20287 58
hebei hongtan Biotechnology Co., Ltd
+86-86-1913198-3935 +8617331935328 sales03@chemcn.cn China 970 58
Capot Chemical Co.,Ltd.
+86-(0)57185586718 +86-13336195806 sales@capot.com China 29791 60
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21634 55
Hangzhou FandaChem Co.,Ltd.
+8615858145714 FandaChem@Gmail.com China 9215 55
Anqing Chico Pharmaceutical Co., Ltd.
15380796838 chloewu@chicopharm.cn CHINA 340 58
career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29884 58

View Lastest Price from (R)-5-bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(R)-5-bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine pictures 2024-11-15 (R)-5-bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine
877399-00-3
US $1.00-0.50 / kg 1kg 99% 200kg Jinan Million Pharmaceutical Co., Ltd
(R)-5-bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine pictures 2024-11-15 (R)-5-bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine
877399-00-3
US $0.00-0.00 / kg 1kg 98% 1 ton Nanjing Fred Technology Co., Ltd
(R)-5-bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine pictures 2024-11-14 (R)-5-bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine
877399-00-3
US $30.00-20.00 / kg 1kg 99% 2000kg hebei hongtan Biotechnology Co., Ltd
(R)-5-bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine [5-Bromo-3-[(1R)-(2,6-dichloro-3-fluorophenyl)ethoxy]pyridin-2-yl]amine [5-Bromo-3-[[(R)-1-(2,6-dichloro-3-fluorophenyl)ethyl]oxy]pyridin-2-yl]amine (R)-5-BroMo-3-[1-(2,6-dichloro-3-fluoro-phenyl)-ethoxy]-pyridin-2-ylaMine (R)-5-broMo-3-[1-(2,6-dichloro-3-fluoropehnyl)ethoxy]pyridin-2-aMine InterMediate Ⅰof Crizotinib (R)-5-broMo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-aMine 2-PyridinaMine, 5-broMo-3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]- Crizotinib-H (R)-5-bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy) yridine-2-amine Chiral intermediate of crizotinib Crizotinib intermediates 1 5-bromo-3-[(1 R)-(2,6-dichloro-3-fluorophenyl) ethoxy] pyridine-2-yl] amine chiral intermediates of Crizotinib chiral intermediates of Crizotinib Company Standards (R)-5-bromo-3-(1-(2,6-dichloro-3-fluorophenyl)etho (R) -5-bromo-3 - (1- (2, 6-dichloro-3-fluorophenyl) ethoxy) pyridine-2-amine (R)-5-bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine ISO 9001:2015 REACH (R)-5-bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin... Crizotinib Impurity 3 5-bromo-3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]pyridin-2-amine (R)-5-bromo-3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]pyridin-2-amine 877399-00-3 C13H10BrCl2FN2O C13H10N2OBrCl2F intermediate 877399-00-3