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AM-2233

AM-2233 Structure
AM-2233 structure
CAS No.
444912-75-8
Chemical Name:
AM-2233
Synonyms
CS-325;AM-2233;1-[(N-Methylpiperidin-2-yl)Methyl]-3-(2-iodobenzoyl)indole;1-[(N-Methylpiperidin-2-yl)methyl]-3-(2-iodobenzoyl)-1H-indole;(2-iodophenyl)-[1-[(1-methylpiperidin-2-yl)methyl]indol-3-yl]methanone;(2-iodophenyl)(1-((1-Methylpiperidin-2-yl)Methyl)-1H-indol-3-yl)Methanone;(2-Iodophenyl)[1-[(1-methyl-2-piperidinyl)methyl]-1H-indol-3-yl]methanone;Methanone, (2-iodophenyl)[1-[(1-methyl-2-piperidinyl)methyl]-1H-indol-3-yl]-;(2-iodanylphenyl)-[1-[[(2S)-1-methylpiperidin-2-yl]methyl]indol-3-yl]methanone
CBNumber:
CB62538880
Molecular Formula:
C22H23IN2O
Molecular Weight:
458.34
MDL Number:
MFCD21603816
MOL File:
444912-75-8.mol
Last updated:2023-06-08 09:01:59

AM-2233 Properties

Boiling point 571.0±30.0 °C(Predicted)
Density 1.48
solubility DMF: 20 mg/ml; DMF:PBS (pH 7.2) (1:9): 0.1 mg/ml; DMSO: 15 mg/ml; Ethanol: 0.5 mg/ml
form A crystalline solid
pka 9.74±0.10(Predicted)
FDA UNII Z489688DK3

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS06
Signal word  Danger
Hazard statements  H413-H301-H319
Precautionary statements  P264-P270-P301+P310-P321-P330-P405-P501-P264-P280-P305+P351+P338-P337+P313P
NFPA 704
0
2 0

AM-2233 Chemical Properties,Uses,Production

Uses

A potent cannabinergic indole analogues as radioiodinatable brain imaging agents for the CB1 cannabinoid receptor. (AM2233) had a very high affinity for the rat CB1 receptor, with most of the affinity residing with the (R)-enantiomer.Synthetic Cannabinoids

AM-2233 Preparation Products And Raw materials

Raw materials

Preparation Products

AM-2233 1-[(N-Methylpiperidin-2-yl)Methyl]-3-(2-iodobenzoyl)indole (2-iodophenyl)(1-((1-Methylpiperidin-2-yl)Methyl)-1H-indol-3-yl)Methanone 1-[(N-Methylpiperidin-2-yl)methyl]-3-(2-iodobenzoyl)-1H-indole (2-Iodophenyl)[1-[(1-methyl-2-piperidinyl)methyl]-1H-indol-3-yl]methanone CS-325 (2-iodophenyl)-[1-[(1-methylpiperidin-2-yl)methyl]indol-3-yl]methanone (2-iodanylphenyl)-[1-[[(2S)-1-methylpiperidin-2-yl]methyl]indol-3-yl]methanone Methanone, (2-iodophenyl)[1-[(1-methyl-2-piperidinyl)methyl]-1H-indol-3-yl]- 444912-75-8 C22H23IN2O Research Chemical Amines Heterocycles Indole Derivatives Intermediates & Fine Chemicals Pharmaceuticals