ChemicalBook >> CAS DataBase List >>N-[2-[(3S)-3-[[4-Hydroxy-4-[5-(pyrimidin-2-yl)pyridin-2-yl]cyclohexyl]amino]pyrrolidin-1-yl]-2-oxoethyl]-3-(trifluoromethyl)benzamide

N-[2-[(3S)-3-[[4-Hydroxy-4-[5-(pyrimidin-2-yl)pyridin-2-yl]cyclohexyl]amino]pyrrolidin-1-yl]-2-oxoethyl]-3-(trifluoromethyl)benzamide

N-[2-[(3S)-3-[[4-Hydroxy-4-[5-(pyrimidin-2-yl)pyridin-2-yl]cyclohexyl]amino]pyrrolidin-1-yl]-2-oxoethyl]-3-(trifluoromethyl)benzamide structure

CAS No.: 857679-55-1

Chemical Name:: N-[2-[(3S)-3-[[4-Hydroxy-4-[5-(pyrimidin-2-yl)pyridin-2-yl]cyclohexyl]amino]pyrrolidin-1-yl]-2-oxoethyl]-3-(trifluoromethyl)benzamide

Synonyms: CS-261;INCB 8761;PF-4136309;(Rac)-PF-4136309;PF-4136309(INCB 8761);(1341224-83-6) incb 8761;(S)-N-(2-(3-((4-Hydroxy-4-(5-(pyrimidin-2-yl)pyridin-2-yl)cyclohexyl)amino)pyrrolidin-1-yl)-2-oxoethyl)-3-(trifluoromethyl)benzamide;N-[2-[(3S)-3-[[4-Hydroxy-4-[5-(pyrimidin-2-yl)pyridin-2-yl]cyclohexyl]amino]pyrrolidin-1-yl]-2-oxoethyl]-3-(trifluoromethyl)benzamide;Benzamide, N-[2-[(3S)-3-[[4-hydroxy-4-[5-(2-pyrimidinyl)-2-pyridinyl]cyclohexyl]amino]-1-pyrrolidinyl]-2-oxoethyl]-3-(trifluoromethyl)-

CBNumber:: CB62554338

Molecular Formula:: C29H31F3N6O3

Molecular Weight:: 568.59

MDL Number:: MFCD22419015

MOL File:: 857679-55-1.mol

MSDS File:: SDS

Last updated:2024-10-28 16:48:35

Request For Quotation

N-[2-[(3S)-3-[[4-Hydroxy-4-[5-(pyrimidin-2-yl)pyridin-2-yl]cyclohexyl]amino]pyrrolidin-1-yl]-2-oxoethyl]-3-(trifluoromethyl)benzamide Properties

Boiling point	712.2±60.0 °C(Predicted)
Density	1.40
storage temp.	Store at -20°C
solubility	DMSO: 100 mg/mL (175.87 mM);Ethanol: 100 mg/mL (175.87 mM)
pka	13.17±0.46(Predicted)
form	Solid
color	Light yellow to yellow
Water Solubility	Water: Insoluble
FDA UNII	3M2595V4KT

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P280-P301+P312-P302+P352-P305+P351+P338

N-[2-[(3S)-3-[[4-Hydroxy-4-[5-(pyrimidin-2-yl)pyridin-2-yl]cyclohexyl]amino]pyrrolidin-1-yl]-2-oxoethyl]-3-(trifluoromethyl)benzamide price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Usbiological	474115	INCB 8761	857679-55-1	100mg	$1932	2021-12-16	Buy
American Custom Chemicals Corporation	INB0001391	N-[2-[(3S)-3-[[4-HYDROXY-4-[5-(PYRIMIDIN-2-YL)PYRIDIN-2-YL]CYCLOHEXYL]AMINO]PYRROLIDIN-1-YL]-2-OXOETHYL]-3-(TRIFLUOROMETHYL)BENZAMIDE 95.00%	857679-55-1	5MG	$345.4	2021-12-16	Buy
Biorbyt Ltd	orb181258	INCB8761 >98%	857679-55-1	100mg	$838.1	2021-12-16	Buy
Biorbyt Ltd	orb181258	INCB8761 >98%	857679-55-1	250mg	$1431.4	2021-12-16	Buy
Biorbyt Ltd	orb181258	INCB8761 >98%	857679-55-1	1000mg	$2691.1	2021-12-16	Buy

Product number	Packaging	Price	Buy
474115	100mg	$1932	Buy
INB0001391	5MG	$345.4	Buy
orb181258	100mg	$838.1	Buy
orb181258	250mg	$1431.4	Buy
orb181258	1000mg	$2691.1	Buy

N-[2-[(3S)-3-[[4-Hydroxy-4-[5-(pyrimidin-2-yl)pyridin-2-yl]cyclohexyl]amino]pyrrolidin-1-yl]-2-oxoethyl]-3-(trifluoromethyl)benzamide Chemical Properties,Uses,Production

Uses

PF 4136309 is a CCR5 receptor antagonists that contributes to the treatment of rheumatoid arthritis.

N-[2-[(3S)-3-[[4-Hydroxy-4-[5-(pyrimidin-2-yl)pyridin-2-yl]cyclohexyl]amino]pyrrolidin-1-yl]-2-oxoethyl]-3-(trifluoromethyl)benzamide Preparation Products And Raw materials

Raw materials

Preparation Products

N-[2-[(3S)-3-[[4-Hydroxy-4-[5-(pyrimidin-2-yl)pyridin-2-yl]cyclohexyl]amino]pyrrolidin-1-yl]-2-oxoethyl]-3-(trifluoromethyl)benzamide Suppliers

Global( 51)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32951	60
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49374	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29814	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	57505	58
TargetMol Chemicals Inc.	+8613564774135	zijue.cai@tsbiochem.com	United States	19863	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131957	58
Shanghai Boyle Chemical Co., Ltd.		sales@boylechem.com	China	2922	55
Chembest Research Laboratories Limited	+86-21-20908456	sales@BioChemBest.com	China	6005	61
ChemCell Biomedicine Co.,Ltd.	020-13556033878 2965585218 13556033878	chemcell@hotmail.com	China	369	52
AdooQ BioScience, LLC	+1 (866) 930-6790	info@adooq.com	United States	2782	58

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
Aladdin Scientific	58
TargetMol Chemicals Inc.	58
Amadis Chemical Company Limited	58
Shanghai Boyle Chemical Co., Ltd.	55
Chembest Research Laboratories Limited	61
ChemCell Biomedicine Co.,Ltd.	52
AdooQ BioScience, LLC	58

View Lastest Price from N-[2-[(3S)-3-[[4-Hydroxy-4-[5-(pyrimidin-2-yl)pyridin-2-yl]cyclohexyl]amino]pyrrolidin-1-yl]-2-oxoethyl]-3-(trifluoromethyl)benzamide manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2024-10-28	(Rac)-PF-4136309（1341224-83-6 Free base) 857679-55-1	US $0.00-0.00 / mg			10g	TargetMol Chemicals Inc.
	2020-01-10	N-[2-[(3S)-3-[[4-Hydroxy-4-[5-(pyrimidin-2-yl)pyridin-2-yl]cyclohexyl]amino]pyrrolidin-1-yl]-2-oxoethyl]-3-(trifluoromethyl)benzamide 857679-55-1	US $1.00 / g	1g	99%	200kg	Career Henan Chemical Co

(Rac)-PF-4136309（1341224-83-6 Free base)
857679-55-1
US $0.00-0.00 / mg
TargetMol Chemicals Inc.

N-[2-[(3S)-3-[[4-Hydroxy-4-[5-(pyrimidin-2-yl)pyridin-2-yl]cyclohexyl]amino]pyrrolidin-1-yl]-2-oxoethyl]-3-(trifluoromethyl)benzamide
857679-55-1
US $1.00 / g
99%
Career Henan Chemical Co

N-[2-[(3S)-3-[[4-Hydroxy-4-[5-(pyrimidin-2-yl)pyridin-2-yl]cyclohexyl]amino]pyrrolidin-1-yl]-2-oxoethyl]-3-(trifluoromethyl)benzamide INCB 8761 PF-4136309 PF-4136309(INCB 8761) CS-261 (1341224-83-6) incb 8761 Benzamide, N-[2-[(3S)-3-[[4-hydroxy-4-[5-(2-pyrimidinyl)-2-pyridinyl]cyclohexyl]amino]-1-pyrrolidinyl]-2-oxoethyl]-3-(trifluoromethyl)- (S)-N-(2-(3-((4-Hydroxy-4-(5-(pyrimidin-2-yl)pyridin-2-yl)cyclohexyl)amino)pyrrolidin-1-yl)-2-oxoethyl)-3-(trifluoromethyl)benzamide (Rac)-PF-4136309 857679-55-1 C29H31F3N6O3