Heterophyllin B
- CAS No.
- 145459-19-4
- Chemical Name:
- Heterophyllin B
- Synonyms
- Heterophylin B;Heterophyllin B;Prince Ginseng Cyclic Peptide B;Cyclo(glycylglycyl-L-leucyl-L-prolyl-L-prolyl-L-prolyl-L-isoleucyl-L-phenylalanyl);Cyclo(glycylglycyl-L-isoleucyl-L-prolyl-L-prolyl-L-prolyl-L-isole ucyl-L-phenylalanyl);(6S,15S,18S,20aS,25aS,30aS)-15-Benzyl-18-((S)-sec-butyl)-6-isobutylicosahydro-1H,25H-tripyrrolo[1,2-a:1',2'-d:1'',2''-g][1,4,7,10,13,16,19,22]octaazacyclotetracosin-5,8,11,14,17,20,25,30(30aH)-octaone;(6S,15S,18S,20aS,25aS,30aS)-15-Benzyl-18-((S)-sec-butyl)-6-isobutylicosahydro-1H,25H-tripyrrolo[1,2-a:1',2'-d:1'',2''-g][1,4,7,10,13,16,19,22]octaazacyclotetracosin-5,8,11,14,17,20,25,30(30aH)-octaone
- CBNumber:
- CB62604877
- Molecular Formula:
- C40H58N8O8
- Molecular Weight:
- 778.94
- MDL Number:
- MFCD22125018
- MOL File:
- 145459-19-4.mol
Heterophyllin B price
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Usbiological | 300415 | Heterophyllin B | 145459-19-4 | 20mg | $490 | 2021-12-16 | Buy |
Biorbyt Ltd | orb105560 | Heterophyllin B >98% | 145459-19-4 | 20mg | $569.5 | 2021-12-16 | Buy |
ChemScene | CS-0016982 | HeterophyllinB ≥98.0% | 145459-19-4 | 25mg | $640 | 2021-12-16 | Buy |
ChemScene | CS-0016982 | HeterophyllinB ≥98.0% | 145459-19-4 | 5mg | $184 | 2021-12-16 | Buy |
ChemScene | CS-0016982 | HeterophyllinB ≥98.0% | 145459-19-4 | 10mg | $320 | 2021-12-16 | Buy |
Heterophyllin B Chemical Properties,Uses,Production
Chemical Properties
White crystal, easily soluble in methanol, derived from Radix Radix.
Uses
Taizishencyclopeptide B has the functions of invigorating qi and blood, invigorating body fluid and invigorating the spleen and stomach. And it was used for content determination/identification/pharmacological experiments, etc.
Biological Activity
Heterophyllin B is an active cyclic peptide isolated from Pseudostellaria heterophylla. It can be used in esophageal cancer research.
in vitro
Heterophyllin B (0-200 μM; 12-48 hours) reduces cell viability in the 75, 100 and 200 μM groups, has no effect on 5, 10, 25 and 50 μM groups.Heterophyllin B (0 -50 μM; 6 hours) suppresses the expression levels of p-PI3K, p-AKT and β-catenin in a dose-dependent manner in ECA-109 cells.
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Cell Viability Assay
Cell Line: | ECA-109 cells |
Concentration: | 5 μM, 10 μM, 25 μM, 50 μM, 75 μM, 100 μM and 200 μM |
Incubation Time: | 12, 24 and 48 hours |
Result: | Decrease cell viability at high concentrations. |
Western Blot Analysis
Cell Line: | ECA-109 cells |
Concentration: td> | 0 μM, 10 μM, 25 μM, 50 μM |
Incubation Time: | 6 hours |
Result: | Decreased the phosphorylation of PI3K/AKT and the expression of β-catenin. |
Heterophyllin B Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3620 | 58 |
Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | scglp@glp-china.com | CHINA | 1824 | 58 |
Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10312 | 58 |
Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | sales@biopurify.com | China | 3777 | 58 |
Shanghai Standard Technology Co., Ltd. | 18502101150 | ft-sales@nature-standard.com | CHINA | 1923 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29825 | 58 |
Wuhan ChemNorm Biotech Co.,Ltd. | +86-27-8439 4403 18971486879 | sales@chemnorm.com | CHINA | 2935 | 58 |
HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418684 +8618949823763 | sales@tnjchem.com | China | 25363 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
View Lastest Price from Heterophyllin B manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
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2023-02-24 | Heterophyllin B
145459-19-4
|
US $0.00 / mg | 5mg | ≥98%(HPLC) | 10 g | Shanghai Standard Technology Co., Ltd. | |
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2020-01-18 | Heterophyllin B
145459-19-4
|
US $3.00 / KG | 1KG | 98% | 1kg , 5kg, 50kg | Career Henan Chemical Co |
-
- Heterophyllin B
145459-19-4
- US $0.00 / mg
- ≥98%(HPLC)
- Shanghai Standard Technology Co., Ltd.
-
- Heterophyllin B
145459-19-4
- US $3.00 / KG
- 98%
- Career Henan Chemical Co