ChemicalBook >> CAS DataBase List >>(S)-N-(1-AMino-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide

(S)-N-(1-AMino-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide

CAS No.
289472-80-6
Chemical Name:
(S)-N-(1-AMino-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide
Synonyms
Bortezomib IMP;BortezoMib IMpurity;Bortezomib Impuirty 41;Bortezomib Impurity 41;ortezomib Amide Impurity;Bortezomib Amide Impurity;Bortezomib USP Impurity B;Bortezomib Related compaund B;Bortezomib USP Related Compoud B;Bortezomib impurity 6/Bortezomib Amide Impurity
CBNumber:
CB62662053
Molecular Formula:
C14H14N4O2
Molecular Weight:
270.29
MDL Number:
MFCD26743605
MOL File:
289472-80-6.mol
MSDS File:
SDS
Last updated:2023-04-23 13:52:06

(S)-N-(1-AMino-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide Properties

Melting point 168-170°C
Boiling point 619.4±55.0 °C(Predicted)
Density 1.280±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility Chloroform (Slightly), DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly)
pka 11.92±0.46(Predicted)
form Solid
color White to Off-White
FDA UNII N46QC2PY7V

(S)-N-(1-AMino-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC A622540 N-[(1S)-2-Amino-2-oxo-1-(phenylmethyl)ethyl]-2-pyrazinecarboxamide 289472-80-6 250mg $805 2021-12-16 Buy
Chemenu CM276681 (S)-N-(1-Amino-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide 95%+ 289472-80-6 1g $1302 2021-12-16 Buy
Alichem 289472806 (S)-N-(1-Amino-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide 289472-80-6 1g $653.12 2021-12-16 Buy
Crysdot CD11152975 (S)-N-(1-Amino-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide 95+% 289472-80-6 1g $780 2021-12-16 Buy
Product number Packaging Price Buy
A622540 250mg $805 Buy
CM276681 1g $1302 Buy
289472806 1g $653.12 Buy
CD11152975 1g $780 Buy

(S)-N-(1-AMino-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide Chemical Properties,Uses,Production

Uses

N-[(1S)-2-Amino-2-oxo-1-(phenylmethyl)ethyl]-2-pyrazinecarboxamide is a metabolite of Bortezomib (B675700), a proteasome inhibitor for the treatment of multiple myeloma and is known to also target the ubiquitin-proteasome pathway.

(S)-N-(1-AMino-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 85)Suppliers
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Standardpharm Co. Ltd.
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Zhengzhou Alfa Chemical Co.,Ltd
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sgtlifesciences pvt ltd
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Hangzhou MolCore BioPharmatech Co.,Ltd.
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ShenZhen Trendseen Biological Technology Co.,Ltd.
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China National Standard Pharmaceutical Corporation Limited
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Zibo Hangyu Biotechnology Development Co., Ltd
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QUALITY CONTROL SOLUTIONS LTD.
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J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 96815 76
Jiangsu Vcare PharmaTech Co., Ltd. 13327700685 sales@vcarepharmatech.com China 310 61
2-PyrazinecarboxaMide, N-[(1S)-2-aMino-2-oxo-1-(phenylMethyl)ethyl]- N-[(1S)-2-Amino-2-oxo-1-(phenylmethyl)ethyl]-2-pyrazinecarboxamide BortezoMib IMpurity Bortezomib Amide Impurity Bortezomib IMP Bortezomib impurity 6/Bortezomib Amide Impurity Bortezomib Related compaund B Bortezomib Impurity 41 Bortezomib USP Related Compoud B (S)-N-(1-Formamido-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide Bortezomib Impuirty 41 Bortezomib USP Impurity B N-[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]pyrazine-2-carboxamide N-((R)-1-(((S)-3-methyl-1-((3aR,4R,6R,7aS)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)butyl)amino)-1-oxo-3- phenylpropan-2-yl)pyrazine-2-carboxamide Bortezomib Related Compund B/ Bortezomib Amide Analog (S)-N-(1-AMino-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaM ortezomib Amide Impurity 289472-80-6