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Miconazole-d5

CAS No.
1216653-50-7
Chemical Name:
Miconazole-d5
Synonyms
Miconazole-d5;1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy-d2]ethyl-d3]-1H-imidazole
CBNumber:
CB62674898
Molecular Formula:
C18H14Cl4N2O
Molecular Weight:
416.12
MDL Number:
MOL File:
1216653-50-7.mol
Last updated:2023-06-08 09:03:02

Miconazole-d5 Properties

storage temp. Store at -20°C
solubility Acetonitrile: soluble,DMSO: Soluble,Methanol: Soluble
form A solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
NFPA 704
0
3 0

Miconazole-d5 Chemical Properties,Uses,Production

Biological Activity

Miconazole-d5 is intended for use as an internal standard for the quantification of miconazole by GC- or LC-MS. Miconazole is an imidazole antifungal.1 It is active against C. parapsilosis, C. pseudotropicalis, C. albicans, C. neoformans, C. tropicalis, and C. guilliermondii (MICs = <0.1-10 μg/ml). It is also active against various Trichophyton species, A. fumigatus, A. niger, B. brasiliensis, and B. dermatitidis. Miconazole (160 mg/kg) prevents infection with T. mentagrophytes and M. canis in mice. It also reduces lesion size in a guinea pig model of C. albicans infection. Formulations containing miconazole have been used in the treatment of various fungal infections.

References

1.Sawyer, P.R., Brogden, R.N., Pinder, R.M., et al.Miconazole: A review of its antifungal activity and therapeutic efficacyDrugs9(6)406-423(1975)

Miconazole-d5 Preparation Products And Raw materials

Raw materials

Preparation Products

Miconazole-d5 Suppliers

Global( 6)Suppliers
Supplier Tel Email Country ProdList Advantage
ChemeGen 中国 18818260767 sales@chemegen.com China 6975 58
Beijing Biocreative Technology Co., Ltd. 15522676233 3007606172@qq.com China 1249 58
Shanghai YuZn Pharm. Technology Co.,Ltd. 15921286451; 15921286451 2010681527@qq.com China 5067 58
Shanghai isotope chemical co.,ltd 021-021-51600108 13062666369 sales@chinaisotope.com China 4274 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 8739 58
Miconazole-d5 1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy-d2]ethyl-d3]-1H-imidazole 1216653-50-7