Chinese Japanese Germany Korea

1(2H)-PyriMidinehexanoic acid, 4-[1,1'-biphenyl]-4-yl-3,4-dihydro-6-Methyl-2-oxo-5-[(phenylMethoxy)carbonyl]-

1(2H)-PyriMidinehexanoic acid, 4-[1,1'-biphenyl]-4-yl-3,4-dihydro-6-Methyl-2-oxo-5-[(phenylMethoxy)carbonyl]- Structure
1(2H)-PyriMidinehexanoic acid, 4-[1,1'-biphenyl]-4-yl-3,4-dihydro-6-Methyl-2-oxo-5-[(phenylMethoxy)carbonyl]- structure
CAS No.
831217-43-7
Chemical Name:
1(2H)-PyriMidinehexanoic acid, 4-[1,1'-biphenyl]-4-yl-3,4-dihydro-6-Methyl-2-oxo-5-[(phenylMethoxy)carbonyl]-
Synonyms
116-9e;116 9e,1169e;116-9e >=98% (HPLC), powder;4-[1,1′-Biphenyl]-4-yl-3,4-dihydro-6-methyl-2-oxo-5-[(phenylmethoxy)carbonyl]-1(2H)-pyrimidinehexanoic acid;1(2H)-PyriMidinehexanoic acid, 4-[1,1'-biphenyl]-4-yl-3,4-dihydro-6-Methyl-2-oxo-5-[(phenylMethoxy)carbonyl]-;6-(4-([1,1'-Biphenyl]-4-yl)-5-((benzyloxy)carbonyl)-6-methyl-2-oxo-3,4-dihydropyrimidin-1(2H)-yl)hexanoic acid;6-(4-([1,1'-biphenyl]-4-yl)-5-((benzyloxy)carbonyl) -6-methyl-2-oxo-3,4-dihydropyrimidin-1(2H)-yl)hexanoic acid
CBNumber:
CB62734895
Molecular Formula:
C31H32N2O5
Molecular Weight:
512.6
MDL Number:
MFCD18632539
MOL File:
831217-43-7.mol
MSDS File:
SDS
Last updated:2023-05-18 11:31:20
Request For Quotation

1(2H)-PyriMidinehexanoic acid, 4-[1,1'-biphenyl]-4-yl-3,4-dihydro-6-Methyl-2-oxo-5-[(phenylMethoxy)carbonyl]- Properties

Boiling point 747.3±60.0 °C(Predicted)
Density 1.205±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO: >20mg/mL
form powder
pka 4.76±0.10(Predicted)
color white to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS06,GHS09
Signal word  Danger
Hazard statements  H301-H410
Precautionary statements  P273-P301+P310+P330
Hazard Codes  T,N
Risk Statements  25-50/53
Safety Statements  45-60-61
RIDADR  UN 2811 6.1 / PGIII
WGK Germany  3

1(2H)-PyriMidinehexanoic acid, 4-[1,1'-biphenyl]-4-yl-3,4-dihydro-6-Methyl-2-oxo-5-[(phenylMethoxy)carbonyl]- price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich E1036 116-9e ≥98% (HPLC), powder 831217-43-7 5mg $159 2024-03-01 Buy
Sigma-Aldrich E1036 116-9e ≥98% (HPLC), powder 831217-43-7 25mg $633 2024-03-01 Buy
Product number Packaging Price Buy
E1036 5mg $159 Buy
E1036 25mg $633 Buy

1(2H)-PyriMidinehexanoic acid, 4-[1,1'-biphenyl]-4-yl-3,4-dihydro-6-Methyl-2-oxo-5-[(phenylMethoxy)carbonyl]- Chemical Properties,Uses,Production

Uses

116-9e has been used as an inhibitor of heat shock protein 70 (Hsp70) co-chaperone HDJ2 (human Ydj1/DNAJA1) to study the influence of HDJ2 on the regulation of ribonucleotide reductase (RNR) activity in HEK293 cells. It has also been used as an Hsp70 inhibitor to study the effect of Hsp70 chaperone on b5‐ops glycosylation in the side populations (SP) HeLa cells.

Biochem/physiol Actions

116-9e is a dihhydropyrimidine compound.

1(2H)-PyriMidinehexanoic acid, 4-[1,1'-biphenyl]-4-yl-3,4-dihydro-6-Methyl-2-oxo-5-[(phenylMethoxy)carbonyl]- synthesis

1468-42-4
5396-89-4
3218-36-8
831217-43-7
Synthesis of 1(2H)-PyriMidinehexanoic acid, 4-[1,1'-biphenyl]-4-yl-3,4-dihydro-6-Methyl-2-oxo-5-[(phenylMethoxy)carbonyl]- from 6-[(AMINOCARBONYL)AMINO]HEXANOIC ACID and BENZYL ACETOACETATE and 4-Biphenylcarboxaldehyde

1(2H)-PyriMidinehexanoic acid, 4-[1,1'-biphenyl]-4-yl-3,4-dihydro-6-Methyl-2-oxo-5-[(phenylMethoxy)carbonyl]- Preparation Products And Raw materials

Raw materials

Preparation Products

5-PyriMidinecarboxylic acid, 4-[1,1'-biphenyl]-4-yl-1-[6-[[2-(butylaMino)-1-[3-(Methoxycarbonyl)-4-(2-Methoxy-2-oxoethoxy)phenyl]-2-oxoethyl]hexylaMino]-6-oxohexyl]-1,2,3,4-tetrahydro-6-Methyl-2-oxo-, phenylMethyl ester

1(2H)-PyriMidinehexanoic acid, 4-[1,1'-biphenyl]-4-yl-3,4-dihydro-6-Methyl-2-oxo-5-[(phenylMethoxy)carbonyl]- Suppliers

Global( 11)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32835 60
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 52927 58
Shanghai ChuangYan Chemical Technology Co., Ltd. 021-11111111 11111111111 546919421@qq.com China 3120 55
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
Energy Chemical 021-58432009 400-005-6266 marketing@energy-chemical.com China 44941 58
Zhengzhou convergence chemical co., LTD 0371-0371-55153829 18003835034 2853979819@qq.com China 9579 58
Bide Pharmatech Ltd. 400-1647117 13681763483 product02@bidepharm.com China 62163 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11975 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 19696 58
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 		60
TargetMol Chemicals Inc. 		58
Aladdin Scientific 		58
Shanghai ChuangYan Chemical Technology Co., Ltd. 55
Sigma-Aldrich 80
Energy Chemical 58
Zhengzhou convergence chemical co., LTD 58
Bide Pharmatech Ltd. 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
TargetMol Chemicals Inc. 58
4-[1,1′-Biphenyl]-4-yl-3,4-dihydro-6-methyl-2-oxo-5-[(phenylmethoxy)carbonyl]-1(2H)-pyrimidinehexanoic acid 116-9e 6-(4-([1,1'-biphenyl]-4-yl)-5-((benzyloxy)carbonyl) -6-methyl-2-oxo-3,4-dihydropyrimidin-1(2H)-yl)hexanoic acid 1(2H)-PyriMidinehexanoic acid, 4-[1,1'-biphenyl]-4-yl-3,4-dihydro-6-Methyl-2-oxo-5-[(phenylMethoxy)carbonyl]- 116-9e >=98% (HPLC), powder 116 9e,1169e 6-(4-([1,1'-Biphenyl]-4-yl)-5-((benzyloxy)carbonyl)-6-methyl-2-oxo-3,4-dihydropyrimidin-1(2H)-yl)hexanoic acid 831217-43-7