ChemicalBook >> CAS DataBase List >>SEN-461
SEN-461
- CAS No.
- 1287727-28-9
- Chemical Name:
- SEN-461
- Synonyms
- SEN461;SEN 461;SEN-461;2,4(1H,3H)-Quinazolinedione, 6-methoxy-3-[[trans-4-[[4-(2-methoxyacetyl)-1-piperazinyl]carbonyl]cyclohexyl]methyl]-1-methyl-
- CBNumber:
- CB63039832
- Molecular Formula:
- C25H34N4O6
- Molecular Weight:
- 486.56
- MDL Number:
- MOL File:
- 1287727-28-9.mol
Last updated:2025-04-18 09:51:19
SEN-461 Chemical Properties,Uses,Production
Description
SEN461 is a Wnt inhibitor/Axin stabilizer.
Uses
SEN461 is a potent and orally active Wnt pathway inhibitor. SEN461 shows effective anti-tumor activity and can be used for GBM research[1].
References
[1] Nencini, A, et al. Structure–activity relationship and properties optimization of a series of Quinazoline-2,4-diones as inhibitors of the canonical Wnt pathway. European Journal of Medicinal Chemistry, 95, 526–545. DOI:10.1016/j.ejmech.2015.03.055
SEN-461 Preparation Products And Raw materials
Raw materials
Preparation Products
SEN-461 Suppliers
Global( 3)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32159 | 58 |
| TargetMol Chemicals Inc. | +8613564774135 | zijue.cai@tsbiochem.com | United States | 19881 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 19727 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |
| TargetMol Chemicals Inc. | 58 |
| TargetMol Chemicals Inc. | 58 |
SEN 461
SEN461
SEN-461
2,4(1H,3H)-Quinazolinedione, 6-methoxy-3-[[trans-4-[[4-(2-methoxyacetyl)-1-piperazinyl]carbonyl]cyclohexyl]methyl]-1-methyl-
1287727-28-9