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Cyclic Arg-Gly-Asp-D-Tyr-Lys

Cyclic Arg-Gly-Asp-D-Tyr-Lys structure

CAS No.: 250612-42-1

Chemical Name:: Cyclic Arg-Gly-Asp-D-Tyr-Lys

Synonyms: Cyclo(RGDyK) TFA;Cyclic Arg-Gly-Asp-D-Tyr-Lys;CCyclic Arg-Gly-Asp-D-Tyr-Lys;Cyclo(RGDyK) trifluoroacetate;Integrin,Cyclo(RGDyK) trifluoroacetate,inhibit,Inhibitor;Cyclo(L-arginylglycyl-L-α-aspartyl-D-tyrosyl-L-lysyl) di2,2,2-Trifluoroacetic acid salt;2,2,2-Trifluoroacetic acid compound with 2-((2S,5R,8S,11S)-8-(4-aminobutyl)-11-(3-guanidinopropyl)-5-(4-hydroxybenzyl)-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentaazacyclopentadecan-2-yl)acetic acid (2:1)

CBNumber:: CB63121443

Molecular Formula:: C29H42F3N9O10

Molecular Weight:: 733.7

MDL Number:: MFCD20134101

MOL File:: 250612-42-1.mol

Last updated:2024-07-02 08:55:13

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Cyclic Arg-Gly-Asp-D-Tyr-Lys Properties

storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
solubility	Soluble in DMSO
form	Solid
color	White to off-white

Cyclic Arg-Gly-Asp-D-Tyr-Lys price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
ChemScene	CS-0019707	Cyclo(RGDyK)trifluoroacetate 99.13%	250612-42-1	5mg	$110	2021-12-16	Buy
ChemScene	CS-0019707	Cyclo(RGDyK)trifluoroacetate 99.13%	250612-42-1	10mg	$180	2021-12-16	Buy
ChemScene	CS-0019707	Cyclo(RGDyK)trifluoroacetate 99.13%	250612-42-1	25mg	$360	2021-12-16	Buy
ChemScene	CS-0019707	Cyclo(RGDyK)trifluoroacetate 99.13%	250612-42-1	50mg	$590	2021-12-16	Buy
ChemScene	CS-0019707	Cyclo(RGDyK)trifluoroacetate 99.13%	250612-42-1	100mg	$890	2021-12-16	Buy

Product number	Packaging	Price	Buy
CS-0019707	5mg	$110	Buy
CS-0019707	10mg	$180	Buy
CS-0019707	25mg	$360	Buy
CS-0019707	50mg	$590	Buy
CS-0019707	100mg	$890	Buy

Cyclic Arg-Gly-Asp-D-Tyr-Lys Chemical Properties,Uses,Production

Biological Activity

Cyclo(RGDyK) is a potent and selective αVβ3 integrin inhibitor with IC50 of 20 nM.

in vitro

Cyclo(RGDyK) showed higher affinity and selectivity for αVβ3 than αVβ5 and αIIbβ3. Cyclo(RGDyK)-bound micelles (TPM) promoted cell-specific uptake of DiI by B16-F10 cells and HUVECs through integrin-mediated endocytosis compared to Cyclo(RGDyK)-free micelles (NPM).

in vivo

Cyclo(RGDyK) (1 nmol, iv) inhibits the increase in αVβ3 integrin expression in the intima of left stenotic carotid arteries in apoE?/? mice.

target

Target	Value
αVβ3 integrin	20 nM

Cyclic Arg-Gly-Asp-D-Tyr-Lys Preparation Products And Raw materials

Raw materials

Preparation Products

Cyclic Arg-Gly-Asp-D-Tyr-Lys Suppliers

Global( 57)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Alpha Biopharmaceuticals Co., Ltd	+86-15542445688	sales@alabiochem.com	China	888	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29814	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	sales@sarms4muscle.com	China	10473	58
Nextpeptide Inc	+86-0571-81612335 +8613336028439	sales@nextpeptide.com	China	19908	58
Alfa Chemistry		Info@alfa-chemistry.com	United States	24072	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6391	58
TargetMol Chemicals Inc.		support@targetmol.com	United States	38465	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	13417589054	trendseenbio@gmail.com	China	11681	58
Hebei Miaoyin Technology Co.,Ltd	+86-17367732028 +86-17367732028	kathy@hbyinsheng.com	China	3512	58

Supplier	Advantage
Alpha Biopharmaceuticals Co., Ltd	58
BOC Sciences	58
career henan chemical co	58
Zhejiang J&C Biological Technology Co.,Limited	58
Nextpeptide Inc	58
Alfa Chemistry	58
InvivoChem	58
TargetMol Chemicals Inc.	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	58
Hebei Miaoyin Technology Co.,Ltd	58

View Lastest Price from Cyclic Arg-Gly-Asp-D-Tyr-Lys manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2020-02-17	Cyclic Arg-Gly-Asp-D-Tyr-Lys 250612-42-1	US $7.00 / KG	1KG	99%	100KG	Career Henan Chemical Co

Cyclic Arg-Gly-Asp-D-Tyr-Lys
250612-42-1
US $7.00 / KG
99%
Career Henan Chemical Co

Cyclic Arg-Gly-Asp-D-Tyr-Lys Spectrum

Cyclic Arg-Gly-Asp-D-Tyr-Lys(250612-42-1)MS

Cyclic Arg-Gly-Asp-D-Tyr-Lys Cyclo(RGDyK) trifluoroacetate CCyclic Arg-Gly-Asp-D-Tyr-Lys Cyclo(L-arginylglycyl-L-α-aspartyl-D-tyrosyl-L-lysyl) di2,2,2-Trifluoroacetic acid salt Cyclo(RGDyK) TFA Integrin,Cyclo(RGDyK) trifluoroacetate,inhibit,Inhibitor 2,2,2-Trifluoroacetic acid compound with 2-((2S,5R,8S,11S)-8-(4-aminobutyl)-11-(3-guanidinopropyl)-5-(4-hydroxybenzyl)-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentaazacyclopentadecan-2-yl)acetic acid (2:1) 250612-42-1