Niraparib intermediate 1

Niraparib intermediate 1 structure

CAS No.: 1476776-84-7

Chemical Name:: Niraparib intermediate 1

Synonyms: Niraparib intermediate 1;(S)-tert-Butyl 3-(4-(7-(tert-Butylcarbamoyl)-2H-indazol-2-yl)phenyl)piperidine-1-carboxylate;tert-Butyl (S)-3-(4-(7-(tert-butylcarbamoyl)-2H-indazol-2-yl)phenyl)piperidine-1-carboxylate;(3s)-3-(4-(7-(((1,1-dimethylethyl)amino)carbonyl)-2h-indazol-2-yl)phenyl)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester;1-Piperidinecarboxylic acid, 3-[4-[7-[[(1,1-dimethylethyl)amino]carbonyl]-2H-indazol-2-yl]phenyl]-, 1,1-dimethylethyl ester, (3S)-

CBNumber:: CB63122233

Molecular Formula:: C28H36N4O3

Molecular Weight:: 476.61

MDL Number:: MFCD31568521

MOL File:: 1476776-84-7.mol

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Niraparib intermediate 1 Properties

Boiling point	571.7±50.0 °C(Predicted)
Density	1.17±0.1 g/cm3(Predicted)
pka	13.84±0.46(Predicted)

Niraparib intermediate 1 Chemical Properties,Uses,Production

Uses

(S)-tert-Butyl 3-(4-(7-(tert-Butylcarbamoyl)-2H-indazol-2-yl)phenyl)piperidine-1-carboxylate is an intermediate of Niraparib (N481400), a novel oral poly(ADP-ribose)polymerase (PARP) inhibitor efficacious in BRCA-1 and -2 mutant tumors.

Niraparib intermediate 1 Preparation Products And Raw materials

Raw materials

Preparation Products

Niraparib intermediate 1 Suppliers

Global( 2)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Amatek Scientific Co. Ltd.	0512-56316828	info@amateksci.com	China	28820	58
Jinan Ruisi Pharmaceutical Technology Co., LTD	0531-69900633 18340090523	changyuan20@163.com	China	1833	58

Supplier	Advantage
Amatek Scientific Co. Ltd.	58
Jinan Ruisi Pharmaceutical Technology Co., LTD	58

Niraparib intermediate 1 1-Piperidinecarboxylic acid, 3-[4-[7-[[(1,1-dimethylethyl)amino]carbonyl]-2H-indazol-2-yl]phenyl]-, 1,1-dimethylethyl ester, (3S)- tert-Butyl (S)-3-(4-(7-(tert-butylcarbamoyl)-2H-indazol-2-yl)phenyl)piperidine-1-carboxylate (S)-tert-Butyl 3-(4-(7-(tert-Butylcarbamoyl)-2H-indazol-2-yl)phenyl)piperidine-1-carboxylate (3s)-3-(4-(7-(((1,1-dimethylethyl)amino)carbonyl)-2h-indazol-2-yl)phenyl)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester 1476776-84-7