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BAR 501 impurity

BAR 501 impurity Structure
BAR 501 impurity structure
CAS No.
1632118-70-7
Chemical Name:
BAR 501 impurity
Synonyms
BAR 501 impurity;Cholane-3,7,24-triol, 6-ethyl-, (3α,5β,6β,7α)-;(3alpha,5beta,6beta,7alpha)-6-Ethylcholane-3,7,24-triol;(3R,5S,6S,7R,8S,9S,10S,13R,14S,17R)-6-ethyl-17-[(2R)-5-hydroxypentan-2-yl]-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol
CBNumber:
CB63160019
Molecular Formula:
C26H46O3
Molecular Weight:
406.64
MDL Number:
MFCD30747751
MOL File:
1632118-70-7.mol
Last updated:2023-09-20 16:43:00
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BAR 501 impurity Properties

Boiling point 527.6±25.0 °C(Predicted)
Density 1.047±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: 20 mg/mL; DMSO: 100μg/ml; Ethanol: 2 mg/mL; Ethanol:PBS (pH 7.2)(1:2): 500μg/ml
form A crystalline solid
pka 14.82±0.70(Predicted)

BAR 501 impurity price More Price(9)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 22461 BAR501 Impurity ≥95% 1632118-70-7 1mg $57 2024-03-01 Buy
Cayman Chemical 22461 BAR501 Impurity ≥95% 1632118-70-7 5mg $233 2024-03-01 Buy
Cayman Chemical 22461 BAR501 Impurity ≥95% 1632118-70-7 10mg $437 2024-03-01 Buy
Biosynth Carbosynth BB178033 BAR 501 impurity 1632118-70-7 50mg $450 2021-12-16 Buy
Biosynth Carbosynth BB178033 BAR 501 impurity 1632118-70-7 100mg $650 2021-12-16 Buy
Product number Packaging Price Buy
22461 1mg $57 Buy
22461 5mg $233 Buy
22461 10mg $437 Buy
BB178033 50mg $450 Buy
BB178033 100mg $650 Buy

BAR 501 impurity Chemical Properties,Uses,Production

Description

BAR501 impurity is an impurity found in the preparation of BAR501 that acts as an agonist of the G protein-coupled bile acid-activated receptor (GP-BAR1). BAR501 impurity (10 μM) induces a 150% increase in luciferase activity in a GP-BAR1 reporter gene assay.1

References

1. Festa, C., Renga, B., D'Amore, C., et al. Exploitation of cholane scaffold for the discovery of potent and selective farnesoid X receptor (FXR) and G-protein coupled bile acid receptor 1 (GP-BAR1) ligands J. Med. Chem. 57(20),8477-8495(2014).

BAR 501 impurity Preparation Products And Raw materials

Raw materials

Preparation Products

BAR 501 impurity Suppliers

Global( 19)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32760 60
BOC Sciences 		+1-631-485-4226 inquiry@bocsci.com United States 19553 58
TargetMol Chemicals Inc. 		+1-781-999-5354 support@targetmol.com United States 19973 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131980 58
Shanghai Boyle Chemical Co., Ltd. sales@boylechem.com China 2923 55
ShangHai Caerulum Pharma Discovery Co., Ltd. 18149758185 sales-cpd@caerulumpharma.com China 3466 58
BOC Sciences 16314854226 info@bocsci.com United States 9926 65
Shanghai Biopharmaleader Co., Ltd. +86 18721201413 sales@biopharmaleader.com China 1720 58
Jinan Yaoyan Pharmaceutical Co., Ltd. jnyaoyan@163.com China 3069 58
Aishilun biotechnology (Shanghai) co., LTD 021-50676523 18019098996 info@acelybio.com China 3967 58
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 		60
BOC Sciences 		58
TargetMol Chemicals Inc. 		58
Amadis Chemical Company Limited 		58
Shanghai Boyle Chemical Co., Ltd. 55
ShangHai Caerulum Pharma Discovery Co., Ltd. 58
BOC Sciences 65
Shanghai Biopharmaleader Co., Ltd. 58
Jinan Yaoyan Pharmaceutical Co., Ltd. 58
Aishilun biotechnology (Shanghai) co., LTD 58

BAR 501 impurity Spectrum

BAR 501 impurity(1632118-70-7)1HNMR
BAR 501 impurity (3R,5S,6S,7R,8S,9S,10S,13R,14S,17R)-6-ethyl-17-[(2R)-5-hydroxypentan-2-yl]-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol (3alpha,5beta,6beta,7alpha)-6-Ethylcholane-3,7,24-triol Cholane-3,7,24-triol, 6-ethyl-, (3α,5β,6β,7α)- 1632118-70-7