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GSK-626616

GSK-626616 structure

CAS No.: 1025821-33-3

Chemical Name:: GSK-626616

Synonyms: GSK-626616;(5Z)-2-[(2,6-Dichlorophenyl)amino]-5-(6-quinoxalinylmethylene)-4(5H)-thiazolone;(Z)-2-((2,6-Dichlorophenyl)amino)-5-(quinoxalin-6-ylmethylene)thiazol-4(5H)-one;4(5H)-Thiazolone, 2-[(2,6-dichlorophenyl)amino]-5-(6-quinoxalinylmethylene)-, (5Z)-;GSK 626616,DYRK,Inhibitor,Dual specificity tyrosine regulated kinase,GSK-626616,GSK626616,inhibit,Dual specificity tyrosine phosphorylation regulated kinase

CBNumber:: CB63303333

Molecular Formula:: C18H10Cl2N4OS

Molecular Weight:: 401.27

MDL Number:: MFCD31689261

MOL File:: 1025821-33-3.mol

Last updated:2024-11-19 23:02:33

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GSK-626616 Properties

Melting point	281 - 282oC
Boiling point	574.8±60.0 °C(Predicted)
Density	1.55±0.1 g/cm3(Predicted)
storage temp.	Refrigerator, under inert atmosphere
solubility	Chloroform (Slightly, Heated), Methanol (Slightly)
pka	-0.94±0.20(Predicted)
form	Solid
color	Pale Yellow to Light Yellow
FDA UNII	OKY0RM282V

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H319-H335-H302-H315

Precautionary statements

P264-P270-P301+P312-P330-P501-P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P

NFPA 704

	0
2		0

GSK-626616 price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	SML3355	GSK626616 ≥98% (HPLC)	1025821-33-3	5MG	$87	2024-03-01	Buy
Sigma-Aldrich	SML3355	GSK626616 ≥98% (HPLC)	1025821-33-3	25MG	$350	2024-03-01	Buy
Tocris	6638	GSK626616 ≥98%(HPLC)	1025821-33-3	50	$861	2021-12-16	Buy
Tocris	6638	GSK626616 ≥98%(HPLC)	1025821-33-3	10	$205	2021-12-16	Buy
TRC	G797853	GSK-626616	1025821-33-3	10mg	$160	2021-12-16	Buy

Product number	Packaging	Price	Buy
SML3355	5MG	$87	Buy
SML3355	25MG	$350	Buy
6638	50	$861	Buy
6638	10	$205	Buy
G797853	10mg	$160	Buy

GSK-626616 Chemical Properties,Uses,Production

Uses

GSK-626616 is a potent and selective DYRK inhibitor (IC50 = 0.7 nM for DYRK3, similar potency for DYRK1 and 2). Exhibits ~20-fold selectivity over casein kinase 2 and negligible activity against a panel of 451 kinases screened. Enhances number of CFU-E stimulated by Epo from human marrow. Increases hemoglobin levels in anemic mice. Orally bioavailable.

storage

Store at +4°C

GSK-626616 Preparation Products And Raw materials

Raw materials

Preparation Products

GSK-626616 Suppliers

Global( 34)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32957	60
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32165	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6391	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49734	58
LEAPCHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	43340	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	57505	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131957	58
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9806	58
Shanghai SuperLan Chemcial Technique Centre	021-2022843681 15618226720	lucy@atkchemical.com	China	10270	58
Nanjing Meihao Pharmaceutical Technology Co., Ltd.	meitaochem@126.com	meitaochem@126.com	China	19103	58

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
TargetMol Chemicals Inc.	58
InvivoChem	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	58
LEAPCHEM CO., LTD.	58
Aladdin Scientific	58
Amadis Chemical Company Limited	58
Shanghai EFE Biological Technology Co., Ltd.	58
Shanghai SuperLan Chemcial Technique Centre	58
Nanjing Meihao Pharmaceutical Technology Co., Ltd.	58

View Lastest Price from GSK-626616 manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2024-11-19	GSK-626616 1025821-33-3	US $44.00-155.00 / mg		99.48%	10g	TargetMol Chemicals Inc.

GSK-626616
1025821-33-3
US $44.00-155.00 / mg
99.48%
TargetMol Chemicals Inc.

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GSK-626616 (5Z)-2-[(2,6-Dichlorophenyl)amino]-5-(6-quinoxalinylmethylene)-4(5H)-thiazolone 4(5H)-Thiazolone, 2-[(2,6-dichlorophenyl)amino]-5-(6-quinoxalinylmethylene)-, (5Z)- GSK 626616,DYRK,Inhibitor,Dual specificity tyrosine regulated kinase,GSK-626616,GSK626616,inhibit,Dual specificity tyrosine phosphorylation regulated kinase (Z)-2-((2,6-Dichlorophenyl)amino)-5-(quinoxalin-6-ylmethylene)thiazol-4(5H)-one 1025821-33-3