ChemicalBook >> CAS DataBase List >>HO-PEG10-CH2CH2COOH

HO-PEG10-CH2CH2COOH

CAS No.
2375611-66-6
Chemical Name:
HO-PEG10-CH2CH2COOH
Synonyms
HO-PEG10-CH2CH2COOH;1-Hydroxy-3,6,9,12,15,18,21,24,27,30-decaoxatritriacontan-33-oic acid;Propanoic acid, 3-[(29-hydroxy-3,6,9,12,15,18,21,24,27-nonaoxanonacos-1-yl)oxy]-;PROTAC Linkers,ADC Linkers,Inhibitor,inhibit,Hydroxy PEG10 acid,Antibody-drug conjugates linkers,Hydroxy-PEG-10-acid,HydroxyPEG10acid
CBNumber:
CB63309421
Molecular Formula:
C23H46O13
Molecular Weight:
530.6
MDL Number:
MFCD34470047
MOL File:
2375611-66-6.mol
Last updated:2024-03-25 20:41:16

HO-PEG10-CH2CH2COOH Properties

Boiling point 614.7±55.0 °C(Predicted)
Density 1.143±0.06 g/cm3(Predicted)
pka 4.28±0.10(Predicted)

HO-PEG10-CH2CH2COOH Chemical Properties,Uses,Production

Biological Activity

Hydroxy-PEG10-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

HO-PEG10-CH2CH2COOH Preparation Products And Raw materials

Raw materials

Preparation Products

HO-PEG10-CH2CH2COOH Suppliers

Global( 10)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Jilin Chinese Academy of Sciences-yanshen Technology
+undefined18143011203 info@chemextension.com China 42057 58
Xian confluore Biological Technology Co., Ltd.
+86-15680926068 +86-15680926068 1924344760@confluore.cn China 2996 58
Xi'an Confluore Biological Technology Co., Ltd. +86-156-80926068 +86-15680926068 1924344760@qq.com China 4824 58
Guangzhou Hongyuan Chemical Co.,Ltd 15817493340 981810490@qq.com China 1566 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 psaitong@jm-bio.com China 29778 58
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd 0431-80514535 19917294565 et@chemextension.com China 5061 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24017 58
Jilin Chinese Academy of Sciences-yanshen Technology 18143011203 ET-market@chemextension.com China 40857 58

View Lastest Price from HO-PEG10-CH2CH2COOH manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Hydroxy-PEG10-acid pictures 2024-03-25 Hydroxy-PEG10-acid
2375611-66-6
US $0.00 / g 1g >98.00% 1g Xian confluore Biological Technology Co., Ltd.
  • Hydroxy-PEG10-acid pictures
  • Hydroxy-PEG10-acid
    2375611-66-6
  • US $0.00 / g
  • >98.00%
  • Xian confluore Biological Technology Co., Ltd.
HO-PEG10-CH2CH2COOH PROTAC Linkers,ADC Linkers,Inhibitor,inhibit,Hydroxy PEG10 acid,Antibody-drug conjugates linkers,Hydroxy-PEG-10-acid,HydroxyPEG10acid Propanoic acid, 3-[(29-hydroxy-3,6,9,12,15,18,21,24,27-nonaoxanonacos-1-yl)oxy]- 1-Hydroxy-3,6,9,12,15,18,21,24,27,30-decaoxatritriacontan-33-oic acid 2375611-66-6