3-(trifluoromethyl)-6,7-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-8(5H)-one

3-(trifluoromethyl)-6,7-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-8(5H)-one structure

CAS No.: 877402-45-4

Chemical Name:: 3-(trifluoromethyl)-6,7-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-8(5H)-one

Synonyms: Sitagliptin Impurity 114;3-(trifluoromethyl)-5H,6H,7H,8H-[1,2,4]triazolo[4,3- a]pyrazin-8-one;3-(Trifluoromethyl)-6,7-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-8(5H)-one;3-(trifluoromethyl)-6,7-dihydro-[l,2,4]triazolo[4,3-a]pyrazin-8(5H)-one;1,2,4-Triazolo[4,3-a]pyrazin-8(5H)-one, 6,7-dihydro-3-(trifluoromethyl)-;3-(trifluoromethyl)-6,7-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-8(5H)-one? (Sitagliptin Impurity）

CBNumber:: CB63312854

Molecular Formula:: C6H5F3N4O

Molecular Weight:: 206.13

MDL Number:: MFCD24609250

MOL File:: 877402-45-4.mol

Last updated:2023-05-15 10:43:40

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3-(trifluoromethyl)-6,7-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-8(5H)-one Properties

Density	1.90±0.1 g/cm3(Predicted)
solubility	DMSO (Slightly), Methanol (Slightly)
pka	12.69±0.20(Predicted)
form	Solid
color	Off-White to Light Grey
FDA UNII	5YJ3TE28KQ

3-(trifluoromethyl)-6,7-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-8(5H)-one Chemical Properties,Uses,Production

Uses

3-(Trifluoromethyl)-6,7-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-8(5H)-one is an intermediate in the synthesis of Sitagliptin Triazecine Analog (S491015). Sitagliptin Triazecine Analog is related to the family of Sitagliptin compounds which has recently been approved for the therapy of type II diabetes.

3-(trifluoromethyl)-6,7-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-8(5H)-one Preparation Products And Raw materials

Raw materials

Preparation Products

3-(trifluoromethyl)-6,7-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-8(5H)-one Suppliers

Global( 25)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32715	60
sgtlifesciences pvt ltd	+8617013299288	dj@sgtlifesciences.com	China	12382	58
China National Standard Pharmaceutical Corporation Limited	+8615391658522	overseasales@yongstandards.com	China	11927	58
Wuhan Jingkang en Biomedical Technology Co., Ltd	+8613720134139	orders@jknbiochem.com	China	4692	58
BOC Sciences	1-631-485-4226; 16314854226	info@bocsci.com	United States	14059	65
ChemStrong Scientific Co.,Ltd	0755-0755-66853366 13670046396	sales@chem-strong.com	China	18018	56
ShangHai Biochempartner Co.,Ltd	17754423994 17754423994	2853530910@QQ.com	China	8019	62
Zhengzhou Acme Chemical Co., Ltd.	0371-0371-55629727 13323845623	2885676761@qq.com	China	9859	58
Yangzhou Changhua Biotechnology Co., Ltd.	13815846020; 13815846020	438399391@qq.com	China	851	58
Nanjing Shizhou Biology Technology Co.,Ltd	13675144456	sean.lv@synzest.com	China	10787	58

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
sgtlifesciences pvt ltd	58
China National Standard Pharmaceutical Corporation Limited	58
Wuhan Jingkang en Biomedical Technology Co., Ltd	58
BOC Sciences	65
ChemStrong Scientific Co.,Ltd	56
ShangHai Biochempartner Co.,Ltd	62
Zhengzhou Acme Chemical Co., Ltd.	58
Yangzhou Changhua Biotechnology Co., Ltd.	58
Nanjing Shizhou Biology Technology Co.,Ltd	58

877402-45-4(3-(trifluoromethyl)-6,7-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-8(5H)-one)Related Search:

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Sitagliptin Impurity 34 2,4,5-TRIFLUOROBENZYL CHLORIDE (R)-methyl 3-acetamido-4-(2,4,5-trifluorophenyl)butanoate Benzenebutanoicacid,b-[[(1,1-diMethylethoxy)carbonyl]aMino]-2,4,5-trifluoro-,Methylester,(bR)- Sitagliptin

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1,2,4-Triazolo[4,3-a]pyrazin-8(5H)-one, 6,7-dihydro-3-(trifluoromethyl)- Sitagliptin Impurity 114 3-(trifluoromethyl)-5H,6H,7H,8H-[1,2,4]triazolo[4,3- a]pyrazin-8-one 3-(trifluoromethyl)-6,7-dihydro-[l,2,4]triazolo[4,3-a]pyrazin-8(5H)-one 3-(trifluoromethyl)-6,7-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-8(5H)-one? (Sitagliptin Impurity） 3-(Trifluoromethyl)-6,7-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-8(5H)-one 877402-45-4