ChemicalBook >> CAS DataBase List >>ISOTETRANDRINE
ISOTETRANDRINE
- CAS No.
- 477-57-6
- Chemical Name:
- ISOTETRANDRINE
- Synonyms
- NSC 97338;isosinomenina;ISOTETRANDRINE;isosinomeninea;1-isotetrandrine;O-METHYLBERBAMINE;(r,s)-tetrandrine;1-Isotetrandrine(8CI);o,o’-dimethylobamegine;BERBAMINE METHYL ETHER
- CBNumber:
- CB6376880
- Molecular Formula:
- C38H42N2O6
- Molecular Weight:
- 622.76
- MDL Number:
- MFCD00236404
- MOL File:
- 477-57-6.mol
- MSDS File:
- SDS
Last updated:2024-08-06 18:38:04
| Melting point | 180-182℃ |
|---|---|
| Boiling point | 710.5±60.0 °C(Predicted) |
| Density | 1.172 |
| RTECS | NX7285000 |
| solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. |
| form | Off-white solid. |
| pka | 7.70±0.20(Predicted) |
| color | White to light yellow |
| EWG's Food Scores | 1 |
| FDA UNII | 84T861CP2N |
ISOTETRANDRINE price More Price(7)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Alfa Aesar | J67081 | Isotetrandrine, 98% | 477-57-6 | 1mg | $120 | 2023-06-20 | Buy |
| TRC | I918015 | Isotetrandrine | 477-57-6 | 50mg | $685 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0001324 | ISOTETRANDRINE 98.00% | 477-57-6 | 25MG | $1270.5 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0001324 | ISOTETRANDRINE 98.00% | 477-57-6 | 1MG | $187.95 | 2021-12-16 | Buy |
| Arctom | AS325629 | Isotetrandrine | 477-57-6 | 5mg | $226 | 2021-12-16 | Buy |
ISOTETRANDRINE Chemical Properties,Uses,Production
Description
A bisbenzylisoquinoline alkaloid, shown to be identical with berbamine methyl ether, this base occurs in A therosperrna rnoschaturn, Berberis japonica and Stephania cephalantha. It is dextrorotatory with [α]17D + 146° or[α]20D + 150.7° (c 0.85, CHC13). When recrystallized from MeOH it forms colourless crystals and furnishes a crystalline dimethiodide, m.p. 242°C. Four methoxyl groups and two methylimino groups are present.
Uses
Isotetrandrine is a biscoclaurine alkaloid inhibitor of G protein activation of PLA2.
target
IL Receptor | NF-kB | MAPK | Nrf2 | HO-1 | JNK
References
Kondo et al., J. Pharrn. Soc., Japan, 58,920 (1938)
Tomita, Fujita, Morai., ibid, 71,226,301 (1951)
Bick, Clezy, Crow., Austral. J. Chern., 9, III (1956)
Synthesis:
Inubushi et ai., Tetrahedron Lett., 3399 (1968)
ISOTETRANDRINE Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 100)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi Dideu Medichem Co. Ltd | +86-29-81139210 +86-18192627656 | 1059@dideu.com | China | 3003 | 58 |
| Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | scglp@glp-china.com | CHINA | 1824 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | sales@biopurify.com | China | 3772 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39894 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49374 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29810 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23541 | 58 |
| Finetech Industry Limited | +86-27-87465837 +8618971612321 | info@finetechnology-ind.com | China | 9639 | 58 |
View Lastest Price from ISOTETRANDRINE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-08-06 | Isotetrandrine
477-57-6
|
US $30.00-20.00 / KG | 1KG | 99% | 200000KG | Shaanxi Dideu Medichem Co. Ltd | |
 |
2020-03-13 | ISOTETRANDRINE
477-57-6
|
US $1.00 / KG | 1KG | 98% HPLC | 10 tons | Career Henan Chemical Co |
-
- Isotetrandrine
477-57-6
- US $30.00-20.00 / KG
- 99%
- Shaanxi Dideu Medichem Co. Ltd
-
- ISOTETRANDRINE
477-57-6
- US $1.00 / KG
- 98% HPLC
- Career Henan Chemical Co
477-57-6(ISOTETRANDRINE)Related Search:
1-isotetrandrine
6,6’,7,12-tetramethoxy-2,2’-dimethyl-berbama
isosinomenina
isosinomeninea
o,o’-dimethylobamegine
o,o’-dimethylstepholine
O-METHYLBERBAMINE
BERBAMINE METHYL ETHER
ISOTETRANDRINE
(r,s)-tetrandrine
(4aS,16aR)-3,4,4a,5,16a,17,18,19-Octahydro-12,21,22,26-tetramethoxy-4,17-dimethyl-16H-1,24:6,9-dietheno-11,15-metheno-2H-pyrido[2',3':17,18][1,11]dioxacycloeicosino[2,3,4-ij]isoquinoline
NSC 97338
16H-1,24:6,9-Dietheno-11,15-metheno-2H-pyrido[2',3':17,18][1,11]dioxacycloeicosino[2,3,4-ij]isoquinoline, 3,4,4a,5,16a,17,18,19-octahydro-12,21,22,26-tetramethoxy-4,17-dimethyl-, (4aS,16aR)-
1-Isotetrandrine(8CI)
O,O'-Dimethylstepholine
Isotetrandrine, Cell-permeable PLA2 inhibitor
477-57-6
C38H42N2O6
Alkaloids