ChemicalBook >> CAS DataBase List >>1-Chloroethyl isopropyl carbonate
1-Chloroethyl isopropyl carbonate
- CAS No.
- 98298-66-9
- Chemical Name:
- 1-Chloroethyl isopropyl carbonate
- Synonyms
- JCC-1;1-Chloroethyl lsopropyl Carbonate;1-CHLOROETHYL ISOPROPYL CARBONATE;1-Chloroethyl Isopropyl Carbonate >1-(isopropoxycarbonyloxy)ethyl chloride;1-Chloroethyl Isopropyl Carbonate (JCC-1);1 CHLORO ETHYL ISPPROPYL CARBONATE (CEIC);1-Chloroethyl isopropyl carbonate (1-CEIC);CARBONIC ACID 1-CHLOROETHYL ISOPROPYL ESTER;1-Chloroethyl Isopropyl Carbonate, 98.0%(GC)
- CBNumber:
- CB6379609
- Molecular Formula:
- C6H11ClO3
- Molecular Weight:
- 166.6
- MDL Number:
- MFCD04038100
- MOL File:
- 98298-66-9.mol
Last updated:2024-10-28 09:31:23
| Boiling point | 70 °C / 15mmHg |
|---|---|
| Density | 1.113±0.06 g/cm3(Predicted) |
| refractive index | 1.4110-1.4150 |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| form | clear liquid |
| color | Colorless to Almost colorless |
| InChI | InChI=1S/C6H11ClO3/c1-4(2)9-6(8)10-5(3)7/h4-5H,1-3H3 |
| InChIKey | XPTPAIJDVFQPJT-UHFFFAOYSA-N |
| SMILES | C(OC(C)C)(=O)OC(Cl)C |
| LogP | 1.37 at 20℃ |
| CAS DataBase Reference | 98298-66-9(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS02,GHS05 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H226-H314 | |||||||||
| Precautionary statements | P210-P233-P240-P241+P242+P243-P260-P264-P280-P301+P330+P331+P310-P303+P361+P353+P310+P363-P304+P340+P310-P305+P351+P338+P310-P370+P378-P403+P235-P405-P501 | |||||||||
| Risk Statements | 10-34 | |||||||||
| Safety Statements | 16-36/37/39 | |||||||||
| RIDADR | 2920 | |||||||||
| HS Code | 2915.90.5010 | |||||||||
| HazardClass | 8/3 | |||||||||
| PackingGroup | II | |||||||||
| NFPA 704 |
|
1-Chloroethyl isopropyl carbonate price More Price(13)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | C1787 | 1-Chloroethyl Isopropyl Carbonate >98.0%(GC) | 98298-66-9 | 25g | $44 | 2024-03-01 | Buy |
| TCI Chemical | C1787 | 1-Chloroethyl Isopropyl Carbonate >98.0%(GC) | 98298-66-9 | 250g | $200 | 2024-03-01 | Buy |
| TRC | C984675 | 1-Chloroethyl Isopropyl Carbonate | 98298-66-9 | 2.5g | $75 | 2021-12-16 | Buy |
| AK Scientific | Z5422 | 1-Chloroethyl Isopropyl Carbonate | 98298-66-9 | 5g | $77 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC139704 | 1-Chloroethyl isopropyl carbonate | 98298-66-9 | 25g | $100 | 2021-12-16 | Buy |
1-Chloroethyl isopropyl carbonate Chemical Properties,Uses,Production
Uses
1-Chloroethyl Isopropyl-d7 Carbonate is an intermediate in the synthesis of Cefpodoxime Proxetil-d7 (C243862). Cefpodoxime Proxetil-d7 is the labelled form of Cefpodoxime Proxetil (C243860), an antibacterial. Cefpodoxime Proxetil is a broad spectrum, orally absorbed third generation cephalosporin, ester prodrug of the active free acid metabolite, Cefpodoxime (C243850).
1-Chloroethyl isopropyl carbonate is an efficient and mild reagent for removing benzyl protecting groups, especially for compounds containing functional groups that are easily reduced.
Synthesis
To a solution of 2-propanol (2.66 mL, 34.97 mmol) and pyridine (3.39 mL, 41.96 mmol), pre-cooled in a dry-ice/acetone bath was slowly added 1-chloroethyl chloroformate. The resulting mixture was allowed to slowly warm to 25° C. overnight, with stirring. After concentration under reduced pressure, the mixture was dissolved in ethyl acetate. The organic layer was washed with brine, dried over sodium sulfate, filtered and concentrated under reduced pressure to give 1-chloroethyl isopropyl carbonate as a pink/orange oil (5.11 g, 88% yield).
1-Chloroethyl isopropyl carbonate Preparation Products And Raw materials
Global( 255)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jiangsu Vcan Advanced Material Co., Ltd. | +86-17306299870 +86-18652789875 | vcanam@vcanam.com | China | 35 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29791 | 60 |
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| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21634 | 55 |
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| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29882 | 58 |
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| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39894 | 58 |
View Lastest Price from 1-Chloroethyl isopropyl carbonate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2022-10-01 | 1-Chloroethyl isopropyl carbonate
98298-66-9
|
US $0.00-0.00 / KG | 1KG | 98% | 1ton | Henan Aochuang Chemical Co.,Ltd. | |
 |
2021-07-13 | 1-Chloroethyl isopropyl carbonate
98298-66-9
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd | |
 |
2021-07-09 | 1-Chloroethyl isopropyl carbonate
98298-66-9
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd |
-
- 1-Chloroethyl isopropyl carbonate
98298-66-9
- US $0.00-0.00 / KG
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- 1-Chloroethyl isopropyl carbonate
98298-66-9
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- 1-Chloroethyl isopropyl carbonate
98298-66-9
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
98298-66-9(1-Chloroethyl isopropyl carbonate)Related Search:
1-CHLOROETHYL ISOPROPYL CARBONATE
CARBONIC ACID 1-CHLOROETHYL ISOPROPYL ESTER
JCC-1
1-Chloroethyl Isopropyl Carbonate (JCC-1)
1 CHLORO ETHYL ISPPROPYL CARBONATE (CEIC)
Carbonic acid, 1-chloroethyl-, 1-methyl-, ethyl ester
1-Chloroethyl lsopropyl Carbonate
1-Chloroethyl Isopropyl Carbonate, 98.0%(GC)
1-CHLOROETHYL ISOPROPYL CARBONATE (JCC-1)(INTERMEDIATE OF CEFPODOXIME PROXETIL (BANAN))
1-chloroethyl isopropyl carbonate (intermediate of cefpodoxime proxetil)
1-(isopropoxycarbonyloxy)ethyl chloride
1-Chloroethyl Isopropyl Carbonate >
1-Chloroethyl isopropyl carbonate (1-CEIC)
Carbonic acid 1-chloro-ethyl ester isopropyl ester
98298-66-9
C6H10ClO3
CARBONATES
(intermediate of cefpodoxime proxetil)
bc0001