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ChemicalBook >> CAS DataBase List >>2-[2-(4-CHLOROPHENYL)-1,3-THIAZOL-4-YL]ACETIC ACID

2-[2-(4-CHLOROPHENYL)-1,3-THIAZOL-4-YL]ACETIC ACID

2-[2-(4-CHLOROPHENYL)-1,3-THIAZOL-4-YL]ACETIC ACID Structure
2-[2-(4-CHLOROPHENYL)-1,3-THIAZOL-4-YL]ACETIC ACID structure
CAS No.
17969-20-9
Chemical Name:
2-[2-(4-CHLOROPHENYL)-1,3-THIAZOL-4-YL]ACETIC ACID
Synonyms
mialex;8L-323S;ici54,450;Fenclozic;fenclozicacid;acidofenclozico;acidumfenclozicum;Acide p-chlorophenyl-2;2-(p-chlorophenyl)-4-thiazoleaceticaci;2-(4-chlorophenyl)-4-thiazoleaceticaci
CBNumber:
CB6384960
Molecular Formula:
C11H8ClNO2S
Molecular Weight:
253.7
MDL Number:
MFCD00721754
MOL File:
17969-20-9.mol
Last updated:2024-11-19 23:02:33
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2-[2-(4-CHLOROPHENYL)-1,3-THIAZOL-4-YL]ACETIC ACID Properties

Melting point 150-152°C
Boiling point 145°C (rough estimate)
Density 1.2270 (rough estimate)
refractive index 1.6300 (estimate)
storage temp. 2-8°C
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
pka 3.83±0.10(Predicted)
color Off-White to Pale Brown
EWG's Food Scores 1
FDA UNII 58SRQ4DV53

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P301+P312
Hazard Codes  Xn
Risk Statements  22
HazardClass  IRRITANT
Toxicity LD50 in rats, mice (mg/kg): 850, 1000 orally; 250, 300 i.v. (Hepworth)

2-[2-(4-CHLOROPHENYL)-1,3-THIAZOL-4-YL]ACETIC ACID price More Price(23)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC F247530 FenclozicAcid 17969-20-9 500mg $275 2021-12-16 Buy
Matrix Scientific 045605 2-[2-(4-Chlorophenyl)-1,3-thiazol-4-yl]acetic acid >95% 17969-20-9 500mg $181 2021-12-16 Buy
Matrix Scientific 045605 2-[2-(4-Chlorophenyl)-1,3-thiazol-4-yl]acetic acid >95% 17969-20-9 1g $228 2021-12-16 Buy
Biosynth Carbosynth FC124498 [2-(4-Chlorophenyl)-1,3-thiazol-4-yl]acetic acid 17969-20-9 100mg $58 2021-12-16 Buy
Biosynth Carbosynth FC124498 [2-(4-Chlorophenyl)-1,3-thiazol-4-yl]acetic acid 17969-20-9 250mg $115 2021-12-16 Buy
Product number Packaging Price Buy
F247530 500mg $275 Buy
045605 500mg $181 Buy
045605 1g $228 Buy
FC124498 100mg $58 Buy
FC124498 250mg $115 Buy

2-[2-(4-CHLOROPHENYL)-1,3-THIAZOL-4-YL]ACETIC ACID Chemical Properties,Uses,Production

Originator

Fenclozic Acid,ZYF Pharm Chemical

Uses

Fenclozic Acid is a a potent antiinflammatory agent with analgesic and antipyretic properties and is a human hepatotoxic drug.

Manufacturing Process

3.7 parts of 2-(4-chlorophenyl)-4-cyanomethylthiazole and 35 parts of 6 N hydrochloric acid are heated under reflux for 2 hours. The solution is cooled by the addition of ice and made alkaline to pH 8 by the addition of 30% aqueous ammonia. The mixture is filtered to remove trace impurities, and an excess of 40% sodium hydroxide solution is then added to the filtrate to cause precipitation of a sodium salt, which is collected by filtration and crystallised from water. There is thus obtained sodium 2-(4-chlorophenyl)thiazol-4- ylacetate, M.P. 13°C (decomposition).
This sodium salt is dissolved in hot water, and the solution is brought to pH 4 by the addition of acetic acid, which causes the precipitation of 2-(4- chlorophenyl)thiazol-4-ylacetic acid. This is collected by filtration, washed with water, and dried in vacuo over phosphorus pentoxide. It has an M.P. 155- 156°C (from ethyl acetate).

Therapeutic Function

Antiinflammatory, Analgesic, Antipyretic

2-[2-(4-CHLOROPHENYL)-1,3-THIAZOL-4-YL]ACETIC ACID Preparation Products And Raw materials

Raw materials

Ammonia Acetic acid Hydrochloric acid

Preparation Products

2-[2-(4-CHLOROPHENYL)-1,3-THIAZOL-4-YL]ACETIC ACID Suppliers

Global( 50)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32165 58
Career Henan Chemica Co 		+86-0371-86658258 +8613203830695 laboratory@coreychem.com China 30240 58
TargetMol Chemicals Inc. 		support@targetmol.com United States 38632 58
LEAPCHEM CO., LTD. 		+86-852-30606658 market18@leapchem.com China 43340 58
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 57505 58
Guangzhou CATO Research Chemicals Inc. 		+86-020-81960175-617 +8615602392859 Intermediate@cato-chem.com China 8056 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131957 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 021-61259108 18621169109 market03@meryer.com China 40228 62
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35896 56
Supplier Advantage
TargetMol Chemicals Inc. 		58
Career Henan Chemica Co 		58
TargetMol Chemicals Inc. 		58
LEAPCHEM CO., LTD. 		58
Aladdin Scientific 		58
Guangzhou CATO Research Chemicals Inc. 		58
Amadis Chemical Company Limited 		58
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
Wuhan Chemwish Technology Co., Ltd 56

View Lastest Price from 2-[2-(4-CHLOROPHENYL)-1,3-THIAZOL-4-YL]ACETIC ACID manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Fenclozic acid pictures 2024-11-19 Fenclozic acid
17969-20-9
 US $50.00-101.00 / mg 96.14% 10g TargetMol Chemicals Inc.
  • Fenclozic acid pictures
  • Fenclozic acid
    17969-20-9
  • US $50.00-101.00 / mg
  • 96.14%
  • TargetMol Chemicals Inc.

2-[2-(4-CHLOROPHENYL)-1,3-THIAZOL-4-YL]ACETIC ACID Spectrum

2-[2-(4-CHLOROPHENYL)-1,3-THIAZOL-4-YL]ACETIC ACID(17969-20-9)1HNMR

17969-20-9(2-[2-(4-CHLOROPHENYL)-1,3-THIAZOL-4-YL]ACETIC ACID)Related Search:

[2-(3-CHLOROPHENYL)-1,3-THIAZOL-4-YL]ACETIC ACID 2-[4-(3-chlorophenyl)-1,3-thiazol-2-yl]acetic acid 2-[4-(2-chlorophenyl)-1,3-thiazol-2-yl]acetic acid [2-(2-CHLOROPHENYL)-1,3-THIAZOL-4-YL]ACETIC ACID 2-[2-(4-CHLOROPHENYL)-5-METHYL-1,3-THIAZOL-4-YL]ACETIC ACID
2-(2-METHYL-1,3-THIAZOL-4-YL)ETHANOL 97+% 2-[2-(4-CHLOROPHENYL)-1,3-THIAZOL-4-YL]ACETIC ACID ISOPROPYL 2-[2-(4-CHLOROPHENYL)-1,3-THIAZOL-4-YL]ACETATE (2-METHYL-THIAZOL-4-YL)-ACETIC ACID (2-PHENYL-THIAZOL-4-YL)-ACETIC ACID

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2-(4-chlorophenyl)-4-thiazoleaceticaci 2-(4-chlorophenyl)-4-thiazoleaceticacid 2-(4-chlorophenyl)-thiazol-4-ylaceticacid 2-(p-chlorophenyl)-4-thiazoleaceticaci 2-(p-chlorophenyl)-4-thiazole-aceticacid 2-(p-chlorophenyl)thiazol-4-ylaceticacid acidep-chlorophenyl-2thiazole-acetique-4 acidofenclozico acidumfenclozicum fenclozicacid ici54,450 mialex 2-[2-(4-CHLOROPHENYL)-1,3-THIAZOL-4-YL]ACETIC ACID [2-(4-CHLOROPHENYL)-1,3-THIAZOL-4-YL]ACETIC ACID 2-[2-(4-chlorophenyl)-1,3-thiazol-4-yl]ethanoic acid 2-[2-(4-chlorophenyl)-4-thiazolyl]acetic acid 2-[2-(4-chlorophenyl)thiazol-4-yl]acetic acid Fenclozic 4-Thiazoleacetic acid, 2-(4-chlorophenyl)- (9CI) 4-THIAZOLEACETIC ACID, 2-(p-CHLOROPHENYL)- 8L-323S Acide p-chlorophenyl-2 4-Thiazoleacetic acid, 2-(4-chlorophenyl)- [2(4Chlorophenyl)1,3thiazol4yl]acetic acid,[2 (4 Chlorophenyl) 1,3 thiazol 4 yl]acetic acid 17969-20-9