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1H-Imidazole-4-carbaldehyde

1H-Imidazole-4-carbaldehyde structure

CAS No.: 3034-50-2

Chemical Name:: 1H-Imidazole-4-carbaldehyde

Synonyms: 1H-Imidazole-5-carbaldehyde;4-FORMYLIMIDAZOLE;4-IMIDAZOLECARBOXALDEHYDE;Imidazole-4-carbaldehyde;4(5)-IMIDAZOLECARBOXALDEHYDE;FPFF;ecarboxaL;4-ImidazoL;FORMYLIMIDAZOLE;4- formaldehyde

CBNumber:: CB6406969

Molecular Formula:: C4H4N2O

Molecular Weight:: 96.09

MDL Number:: MFCD00173726

MOL File:: 3034-50-2.mol

MSDS File:: SDS

Last updated:2025-04-24 21:50:42

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1H-Imidazole-4-carbaldehyde Properties

Melting point	174-177 °C (lit.)
Boiling point	367.8±15.0 °C(Predicted)
Density	1.322±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	Soluble in DMSO, methanol.
pka	11.05±0.10(Predicted)
form	Solid
color	Light Tan
Sensitive	Air Sensitive
InChIKey	ZQEXIXXJFSQPNA-UHFFFAOYSA-N
CAS DataBase Reference	3034-50-2(CAS DataBase Reference)
FDA UNII	DWG32KT6XA
UNSPSC Code	12352005
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P264-P271-P280-P302+P352-P305+P351+P338

Hazard Codes

Xi,Xn

Risk Statements

36/37/38-20/21/22

Safety Statements

26-36-36/37/39

WGK Germany

Hazard Note

Irritant

HS Code

29332900

NFPA 704

	1
2		0

1H-Imidazole-4-carbaldehyde price More Price(34)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	456128	4-Imidazolecarboxaldehyde 98%	3034-50-2	1g	$20.84	2024-03-01	Buy
Sigma-Aldrich	456128	4-Imidazolecarboxaldehyde 98%	3034-50-2	5g	$172	2024-03-01	Buy
TCI Chemical	I0636	Imidazole-4-carboxaldehyde >98.0%(GC)(T)	3034-50-2	1g	$33	2024-03-01	Buy
TCI Chemical	I0636	Imidazole-4-carboxaldehyde >98.0%(GC)(T)	3034-50-2	5g	$98	2024-03-01	Buy
Alfa Aesar	B25050	Imidazole-4-carboxaldehyde, 97%	3034-50-2	1g	$30.65	2024-03-01	Buy

Product number	Packaging	Price	Buy
456128	1g	$20.84	Buy
456128	5g	$172	Buy
I0636	1g	$33	Buy
I0636	5g	$98	Buy
B25050	1g	$30.65	Buy

1H-Imidazole-4-carbaldehyde Chemical Properties,Uses,Production

Chemical Properties

White to light yellow powder

Uses

1H-Imidazole-4-carbaldehyde is a 4-formyl derivative of imidazole used in the preparation of C17,20-lyase inhibitor for the treatment of androgen-dependent prostate cancer. It is also used in the synthesis of other biologically active compounds such as antimalarial drugs, fabrication of colorimetric chemosensor.

Application

1H-Imidazole-4-carbaldehyde may be used in the following studies: Synthesis of new donor-Π-acceptor (D-Π-A) type dye. Preparation of ethyl, n-dodecyl and n-hexadecyl esters of urocanic acid (4-imidazoleacrylic acid). Fabrication of colorimetric chemosensor. Synthesis of chiral nickel(II) complex, [Ni(II)H3L](ClO4)2, having an achiral ligand H3L (tris{2-(4-imidazolyl)methyliminoethyl}amine).

Synthesis

To a solution of 4-bromo-1H-imidazole in dry THF at 0 ℃ was added, a 2 M solution of i-PrMgCl in THF for 5 min. The clear solution was stirred at that temperature for an additional 5 min, and a 2.5 M solution of n-BuLi in hexanes was added dropwise for 5 min while maintaining the temperature below 20 ℃. The resulting mixture was stirred at that temperature for 0.5 h, and dry DMF was added to 20℃. The mixture was warmed to 20 ℃ in 0.5 h and quenched with water (6 mL). After stirring for 10 min, the phases were separated, and the water phase was extracted one additional time with ethyl acetate. After purification to afford 1H-Imidazole-4-carbaldehyde as an off-white solid, 0.36 g (yield: 85%).

1H-Imidazole-4-carbaldehyde synthesis

Synthesis of 1H-Imidazole-4-carbaldehyde from Imidazole-4-methanol

1H-Imidazole-4-carbaldehyde Preparation Products And Raw materials

Raw materials

Hydrogen Sulfide 4,5-Imidazoledicarboxylic acid PICRIC ACID Ammonium hydroxide Acetic anhydride

N,N-Dimethylformamide Sodium sulfite Manganese dioxide Formaldehyde Triethylamine

D(-)-Fructose 1,4-Dioxane Imidazole Diethyl ether Benzene

Ammonium chloride Iodine Hydrochloric acid Copper(II) sulfate Bromoethane

Triphenylmethyl Chloride Isopropyl alcohol Magnesium Sodium carbonate Ammonia

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Preparation Products

2-(3H-Imidazol-4-yl)-ethylamine

1H-Imidazole-4-carbaldehyde Suppliers

Global( 535)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Nanjing MSN chemical Co., Ltd	25-57015632 +8618913029712	export@msnchem.com	China	26	34
Lewoo Pharmatech(Shanghai)Co.,Ltd	+86-15800805830 +86-15800805830	miao@lewoopharma.com.cn	China	184	58
Hebei Chuanghai Biotechnology Co., Ltd	+8615531157085	abby@chuanghaibio.com	China	8808	58
Hebei Mujin Biotechnology Co.,Ltd	+86 13288715578 +8613288715578	sales@hbmojin.com	China	12806	58
Hebei Chuanghai Biotechnology Co,.LTD	+86-13131129325	sales1@chuanghaibio.com	China	5868	58
Hebei Zhuanglai Chemical Trading Co Ltd	+86-16264648883 +86-16264648883	niki@zlchemi.com	China	7245	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29730	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-+86-371-66670886	info@dakenam.com	China	19843	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21628	55
Nanjing ChemLin Chemical Industry Co., Ltd.	025-83697070	product@chemlin.com.cn	CHINA	3009	60

Supplier	Advantage
Nanjing MSN chemical Co., Ltd	34
Lewoo Pharmatech(Shanghai)Co.,Ltd	58
Hebei Chuanghai Biotechnology Co., Ltd	58
Hebei Mujin Biotechnology Co.,Ltd	58
Hebei Chuanghai Biotechnology Co,.LTD	58
Hebei Zhuanglai Chemical Trading Co Ltd	58
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
Nanjing ChemLin Chemical Industry Co., Ltd.	60

1H-Imidazole-4-carbaldehyde: properties, applications and safety
1H-Imidazole-4-carbaldehyde is valuable for diverse applications, but strict safety measures are essential when handling it.
Nov 29，2023

1H-Imidazole-4-carbaldehyde - Reaction / Application on synthetic works
1H-Imidazole-4-carbaldehyde is a 4-formyl derivative of imidazole used in the preparation of C17,20-lyase inhibitor for the tr....
Nov 19，2019

View Lastest Price from 1H-Imidazole-4-carbaldehyde manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-04-28	1H-Imidazole-4-carbaldehyde 3034-50-2	US $0.00-0.00 / kg	1kg	99.32%	1000kg	WUHAN FORTUNA CHEMICAL CO., LTD
2025-04-28	1H-Imidazole-4-carbaldehyde 3034-50-2	US $10.00 / kg	1kg	99%	20 ton	Hebei Zhuanglai Chemical Trading Co Ltd
2025-04-23	1H-Imidazole-4-carbaldehyde 3034-50-2	US $10.00 / KG	1KG	99%	5tons	Hebei Chuanghai Biotechnology Co., Ltd

1H-Imidazole-4-carbaldehyde
3034-50-2
US $0.00-0.00 / kg
99.32%
WUHAN FORTUNA CHEMICAL CO., LTD

1H-Imidazole-4-carbaldehyde
3034-50-2
US $10.00 / kg
99%
Hebei Zhuanglai Chemical Trading Co Ltd

1H-Imidazole-4-carbaldehyde
3034-50-2
US $10.00 / KG
99%
Hebei Chuanghai Biotechnology Co., Ltd

1H-Imidazole-4-carbaldehyde Spectrum

1H-Imidazole-4-carbaldehyde(3034-50-2)¹HNMR 1H-Imidazole-4-carbaldehyde(3034-50-2)IR

3034-50-2(1H-Imidazole-4-carbaldehyde)Related Search:

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1H-IMIDAZOLE-4-CARBOXALDEHYDE 1H-IMIDAZOLE-4-CARBALDEHYDE IMIDAZOLE-4-CARBOXALDEHYDE FORMYLIMIDAZOLE 4-Formylimidazole 98% 4(5)-Imidazol carboxy aldehyde 4-Formylimidazole98% 4-FORMYLIMIDAZOLE (4(5)-IMIDAZOLECARBOXALDEHYDE) imidazole-4-carboxaldehde 4(5)-Imidazolecarboxaldehyde 98% 5-Imidazolecarboxaldehyde 1H-Imidazole-4-carbaldehyde,97% Imidazole-4-carbaldehyde 4-Imidazolecarbaldehyde 1H-imidazole-5-carbaldehyde Imidazole-4-carboxaldehyde ,98% 4-Imidazolecarboxaldehyde,5-Imidazolecarboxaldehyde 1H-Imidazole-4-carba 1H-Imidazole-4-carboxaldehyde 98% 1H-IMidazole-5-carboxaldehyde 4-Formyl-1H-imidazole 1H-IMidazole-4-carbaldehydee 4-IMidazolecarboxaldehyde 98% 4-forMyl iMidazoles Imidazole-4-carboxaldehyde,97% Imidazole-4(5)-carbaldehyde 4- formaldehyde 3H-IMIDAZOLE-4-CARBALDEHYDE 4-ImidazoL ecarboxaL 1H-Imidazole-4-carbaldehyde 3034-50-2 Imidazole-4-carboxaldehyde 3034-50-2 1H-Imidazole-4-carbaldehyde 3034-50-2 1H-Imidazole-4-carbaldehyde price 3034-50-2 4-Imidazolecarboxaldehyde 4-Formylimidazole 1H-Imidazole-5-carboxaldehyde 1H-Imidazole-4-carboxaldehyde Imidazole-4-Carbaldehyde 4(5)-IMIDAZOLECARBOXALDEHYDE 1H-IMIDAZOLE-4-CARBALDEHYDE 1H-IMIDAZOLE-4-CARBOXALDEHYDE 4(5)-IMIDAZOLECARBOXALDEHYDE 4-FORMYLIMIDAZOLE 4-IMIDAZOLECARBOXALDEHYDE IMIDAZOLE-4-CARBOXALDEHYDE FORMYLIMIDAZOLE 4-Formylimidazole 98% 4(5)-Imidazol carboxy aldehyde 4-Formylimidazole98% Imidazole-4-carbaldehyde 4-FORMYLIMIDAZOLE (4(5)-IMIDAZOLECARBOXALDEHYDE) imidazole-4-carboxaldehde 4(5)-Imidazolecarboxaldehyde 98% 5-Imidazolecarboxaldehyde 1H-Imidazole-5-carbaldehyde 4-aldehydeimidazole Imidazole-4-carboxaldehyde> 1H-Imidazole-4-carbaldehyde ISO 9001：2015 REACH FPFF 4-Imidazolecarboxaldehyde pure, 98% 4(5)-IMIDAZOLECARBOXALDEHYDE 4-IMIDAZOLECARBOXALDEHYDE 4-FORMYLIMIDAZOLE Imidazole-4-carbaldehyde 1H-Imidazole-5-carbaldehyde IMIDAZOL-4-CARBOXALDEHYDE 1-H-Imidazole-4-carboxaldehido Imidazole-4-carboxaldehyde (8CI) 4-imidazole formaldehyde 3034-50-2 ALDEHYDE Building Blocks Heterocyclic Building Blocks Imidazoles Heterocycle-other series Giracodazole Imidazoles & Benzimidazoles Heterocycles series Aldehydes Imidazoles & Benzimidazoles Imidaxoles