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(S)-(+)-2-[HYDROXY(DIPHENYL)METHYL]-1-METHYLPYRROLIDINE

(S)-(+)-2-[HYDROXY(DIPHENYL)METHYL]-1-METHYLPYRROLIDINE structure

CAS No.: 110529-22-1

Chemical Name:: (S)-(+)-2-[HYDROXY(DIPHENYL)METHYL]-1-METHYLPYRROLIDINE

Synonyms: (2S)-(+)-N-Methyl-α;(S)-A,A-DIPHENYLMETHYLPROLINOL;(s)-α,α-Diphenylmethylprolinol;1,1-Diphenyl-N-methyl-L-prolinol;α,α-diphenyl-n-methyl-l-prolinol;à,à-diphenyl-n-methyl-l-prolinol;a,a-Diphenyl-N-methyl-L-prolinol;(S)-N-Methyl-alpha,alpha-diphenyl;(-)-α,α-Diphenyl-N-methyl-D-prolinol;(S)-ALPHA,ALPHA-DIPHENYLMETHYLPROLINOL

CBNumber:: CB6408372

Molecular Formula:: C18H21NO

Molecular Weight:: 267.37

MDL Number:: MFCD00145245

MOL File:: 110529-22-1.mol

Last updated:2025-01-27 09:38:02

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(S)-(+)-2-[HYDROXY(DIPHENYL)METHYL]-1-METHYLPYRROLIDINE Properties

Melting point	66-72 °C
alpha	+52° (c=1, CHCl3)
Boiling point	406.8±25.0 °C(Predicted)
Density	1.116±0.06 g/cm3(Predicted)
refractive index	55 ° (C=1, CHCl3)
storage temp.	Sealed in dry,2-8°C
solubility	sol hexane, benzene, toluene, Et2O, cyclohexane, dichloromethane
pka	13.15±0.29(Predicted)
form	Powder
color	white to pale-yellow
optical activity	[α]20/D +55±3°, c = 1% in chloroform stab. with amylenes
BRN	4749387
CAS DataBase Reference	110529-22-1(CAS DataBase Reference)
UNSPSC Code	12352005
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P305+P351+P338

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-36

WGK Germany

10-34

HS Code

29339900

NFPA 704

	1
2		0

(S)-(+)-2-[HYDROXY(DIPHENYL)METHYL]-1-METHYLPYRROLIDINE price More Price(30)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	H0768	(S)-(+)-2-[Hydroxy(diphenyl)methyl]-1-methylpyrrolidine >98.0%(GC)	110529-22-1	1g	$201	2024-03-01	Buy
TCI Chemical	H0768	(S)-(+)-2-[Hydroxy(diphenyl)methyl]-1-methylpyrrolidine >98.0%(GC)	110529-22-1	5g	$805	2024-03-01	Buy
Alfa Aesar	L19399	alpha,alpha-Diphenyl-N-methyl-L-prolinol, 97% ee 99+%	110529-22-1	250mg	$83.3	2021-12-16	Buy
Strem Chemicals	07-1171	(2S)-(+)-N-Methyl-α,α-diphenyl-2-pyrrolidinemethanol, min. 98%	110529-22-1	100mg	$47	2024-03-01	Buy
Strem Chemicals	07-1171	(2S)-(+)-N-Methyl-α,α-diphenyl-2-pyrrolidinemethanol, min. 98%	110529-22-1	250mg	$99	2024-03-01	Buy

Product number	Packaging	Price	Buy
H0768	1g	$201	Buy
H0768	5g	$805	Buy
L19399	250mg	$83.3	Buy
07-1171	100mg	$47	Buy
07-1171	250mg	$99	Buy

(S)-(+)-2-[HYDROXY(DIPHENYL)METHYL]-1-METHYLPYRROLIDINE Chemical Properties,Uses,Production

Reactions

Catalyst for the enantioselective addition of diethylzinc to α,β-unsaturated aldehydes Reactions of 110529-22-1

Chemical Properties

white to slightly yellow crystalline powder

Uses

(S)-(+)-2-[Hydroxy(diphenyl)methyl]-1-methylpyrrolidine is used for chiral ligand for the enantioselective addition of dialkylzincs, alkynylzinc, and cyanomethylzinc bromide to aldehydes; chiral ligand for the enantioselective Reformatsky reaction; chiral ligand for the enantioselective Diels-Alder reaction; chiral auxiliary for asymmetric polymerization.

Preparation

Reaction of Phenylmagnesium Bromide with (S)-N-[(benzyloxy)carbonyl]proline methyl ester and subsequent reduction with Lithium Aluminum Hydride affords the (S)-(+)-2-[Hydroxy(diphenyl)methyl]-1-methylpyrrolidine in 83% overall yield.

(S)-(+)-2-[HYDROXY(DIPHENYL)METHYL]-1-METHYLPYRROLIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

(S)-(+)-2-[HYDROXY(DIPHENYL)METHYL]-1-METHYLPYRROLIDINE Suppliers

Global( 121)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-+86-371-66670886	info@dakenam.com	China	19819	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28172	58
Chongqing Chemdad Co., Ltd	+86-023-6139-8061 +86-86-13650506873	sales@chemdad.com	China	39894	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
Wuhan Chemwish Technology Co., Ltd	027-67849912	sales@chemwish.com	CHINA	10821	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49732	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29808	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	22793	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418684 +8618949823763	sales@tnjchem.com	China	25356	58
Aladdin Scientific		tp@aladdinsci.com	United States	57505	58

Supplier	Advantage
Shanghai Daken Advanced Materials Co.,Ltd	58
Hubei Jusheng Technology Co.,Ltd.	58
Chongqing Chemdad Co., Ltd	58
Alchem Pharmtech,Inc.	58
Wuhan Chemwish Technology Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
Dideu Industries Group Limited	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
Aladdin Scientific	58

View Lastest Price from (S)-(+)-2-[HYDROXY(DIPHENYL)METHYL]-1-METHYLPYRROLIDINE manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2020-01-10	(S)-(+)-2-[HYDROXY(DIPHENYL)METHYL]-1-METHYLPYRROLIDINE 110529-22-1	US $2.00 / KG	1g	98%MIN	ASK	Career Henan Chemical Co

(S)-(+)-2-[HYDROXY(DIPHENYL)METHYL]-1-METHYLPYRROLIDINE
110529-22-1
US $2.00 / KG
98%MIN
Career Henan Chemical Co

110529-22-1((S)-(+)-2-[HYDROXY(DIPHENYL)METHYL]-1-METHYLPYRROLIDINE)Related Search:

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1of4

a,a-Diphenyl-N-methyl-L-prolinol (s)-n-methyl-à,à-diphenylpyrrolidinemethanol (s)-α,α-diphenyl-n-methyl-2-pyrrolidinemethanol à,à-diphenyl-n-methyl-l-prolinol α,α-diphenyl-n-methyl-l-prolinol 1,1-Diphenyl-N-methyl-L-prolinol ALPHA,ALPHA-DIPHENYL-N-METHYL-L-PROLINOL , EE 99% ɑ,ɑ-Diphenyl-N-methyl-L-prolinol, 97%, ee 99+% (S)-N-Methyl-alpha,alpha-diphenyl alpha,alpha-Diphenyl-N-methyl-L-prolinol, 97%, ee 99+% ^a,^a-Diphenyl-N-methyl-L-prolinol, 97%, ee 99+% (S)-alpha,alpha-Diphenylmethylprolinol,98% [( S)-α,α-Diphenyl-N-methyl-2-pyrrolidnemethanol] S-N-methyl-α,α-Diphenyl-2-pyrrolidinemethanol (2S)-2-[Hydroxy(diphenyl)methyl]-1-methylpyrrolidine [(2S)-1-Methylpyrrolidin-2-yl](diphenyl)methanol, alpha,alpha-Diphenyl-N-methyl-L-prolinol α,α-Diphenyl-N-Methyl-L-prolinol >=96.0% (suM of enantioMers, GC) (S)-(+)-DIPHENYL(1-METHYLPYRROLIDIN-2-YL)METHANOL (S)-ALPHA,ALPHA-DIPHENYLMETHYLPROLINOL (S)-ALPHA,ALPHA-DIPHENYL-N-METHYL-2-PYRROLIDINEMETHANOL (S)-N-METHYL- ALPHA,ALPHA -DIPHENYL-2-PYRROLIDINE METHANOL (S)-A,A-N-METHYL DIPHENYL-2-PYRROLIDINE METHANOL (S)-A,A-DIPHENYLMETHYLPROLINOL (S)-A,A-DIPHENYL-N-METHYL-2-PYRROLIDINEMETHANOL (2S)-N-Methyl-α,α-diphenyl-2-pyrrolidinemethanol (2S)-N-Methyl-α,α-diphenyl-2-pyrrolidinemethanol,99%e.e. ALPHA,ALPHA-DIPHENYL-N-METHYL-L-PROLINOL (2S)-1-METHYL-ALPHA,ALPHA-DIPHENYL-2-PYRROLIDINEMETHANOL (S)-(+)-2-[HYDROXY(DIPHENYL)METHYL]-1-METHYLPYRROLIDINE (S)-N-Methyl-alpha,alpha-diphenylpyrrolidinemethanol Hydroxydiphenylmethylmethylpyrrolidine (2S)-(+)-N-Methyl-α,α-diphenyl-2-pyrrolidinemethanol, min. 98% (2S)-(+)-N-Methyl-α (S)-N-Methyl-a,a-diphenyl-2-pyrrolidinemethanol α,α-Diphenyl-N-methyl-L-prolinol, 97%, for synthesis (S)-(+)-2-[Hydroxy(diphenyl)methyl]-1-methylpyrrolidine> 2-Pyrrolidinemethanol, 1-methyl-α,α-diphenyl-, (2S)- (S)-(+)-2-[HYDROXY(DIPHENYL)METHYL]-1-METHYLPYRROLIDINE USP/EP/BP (s)-α,α-Diphenylmethylprolinol (S)-(1-Methylpyrrolidin-2-yl)diphenylmethanol (-)-α,α-Diphenyl-N-methyl-D-prolinol α,α-Diphenyl-N-methyl-L-prolinol 110529-22-1 Proline-Based Organocatalysts Chiral Catalysts, Ligands, and Reagents Asymmetric Synthesis Asymmetric Synthesis Synthetic Organic Chemistry