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ChemicalBook >> CAS DataBase List >>2,2',5,5'-Tetrachlorobenzidine

2,2',5,5'-Tetrachlorobenzidine

2,2',5,5'-Tetrachlorobenzidine Structure
2,2',5,5'-Tetrachlorobenzidine structure
CAS No.
15721-02-5
Chemical Name:
2,2',5,5'-Tetrachlorobenzidine
Synonyms
TCB;PK3;OIP3;PKM1 active human;2,2',5,5'-Tetrachlor;2,2',5,5'-TETRACHLOROBENZIDINE;2,2’,5,5’-tetrachloro-benzidin;3,3’,6,6’-tetrachlorobenzidine;2,2',5,5'-tetrachlorobenzidine;2,2,5,5-TETRACHLOROBENZIDINE 98+%
CBNumber:
CB6411730
Molecular Formula:
C12H8Cl4N2
Molecular Weight:
322.02
MDL Number:
MFCD00043918
MOL File:
15721-02-5.mol
Last updated:2025-01-27 09:38:02
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2,2',5,5'-Tetrachlorobenzidine Properties

Melting point 135-140 °C(lit.)
Boiling point 477.67°C (rough estimate)
Density 1.5309 (rough estimate)
refractive index 1.6000 (estimate)
storage temp. -70°C
solubility soluble in Methanol
form powder to crystal
pka 1.58±0.13(Predicted)
color Light yellow to Yellow to Orange
biological source human
Water Solubility water: soluble
CAS DataBase Reference 15721-02-5(CAS DataBase Reference)
FDA UNII ICS5PD3141
IARC 3 (Vol. 27, Sup 7) 1987
EPA Substance Registry System [1,1'-Biphenyl]-4,4'-diamine, 2,2',5,5'-tetrachloro- (15721-02-5)
UNSPSC Code 12352200
NACRES NA.32

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
Hazard Codes  T
Risk Statements  61
Safety Statements  53-45
WGK Germany  3
RTECS  DD1751000
HS Code  2921.59.8090

2,2',5,5'-Tetrachlorobenzidine price More Price(17)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SRP0415 PKM1 active human recombinant, expressed in E. coli, ≥80% (SDS-PAGE) 1644286-11-2 20μG $653 2024-03-01 Buy
TCI Chemical T0933 2,2',5,5'-Tetrachlorobenzidine >98.0%(HPLC)(N) 15721-02-5 25g $70 2024-03-01 Buy
TCI Chemical T0933 2,2',5,5'-Tetrachlorobenzidine >98.0%(HPLC)(N) 15721-02-5 500g $576 2024-03-01 Buy
TRC T204568 2,2'',5,5''-Tetrachlorobenzidine 15721-02-5 250mg $45 2021-12-16 Buy
TRC T204568 2,2'',5,5''-Tetrachlorobenzidine 15721-02-5 2.5g $75 2021-12-16 Buy
Product number Packaging Price Buy
SRP0415 20μG $653 Buy
T0933 25g $70 Buy
T0933 500g $576 Buy
T204568 250mg $45 Buy
T204568 2.5g $75 Buy

2,2',5,5'-Tetrachlorobenzidine Chemical Properties,Uses,Production

Uses

PKM1active human has been used in:

  • cell-based kinase assay to study the ability of a compound to inhibit the kinase activity of PKM1.
  • oxidative stress experiments on PKM2.
  • Co-immunoprecipitation (Co-IP) to determine pyruvate kinase M2 (PKM2) as a novel direct binding partner of phosphoserine aminotransferase 1 (PSAT1).

Definition

ChEBI: 2,2',5,5'-Tetrachlorobenzidine is a member of biphenyls and a dichlorobenzene.

Production Methods

2,2' ,5,5' -Tetrachlorobenzidine is made by the reduction of 2,5-dichloronitrobenzene with zinc dust and sodium hydroxide solution. The subsequent rearrangement is carried out using sulfuric acid or hydrochloric acid. The dihydrochloride melts at 230 ℃. Tetrachlorobenzidine is marketed as the free base and is used to produce yellow pigments.

Biological Activity

Pyruvate kinase (PK) catalyzes the dephosphorylation of phosphoenolpyruvate(PEP) into pyruvate. It is also involved in glycolysis by releasing ATP.Allosteric effects and intracellular signal transduction regulate the enzymaticactivity of PKM1. PKM1 is involved in several biological processes such asmetabolic reprogramming, and innate and acquired immune response. Itparticipates in protein interactions, protein synthesis, glycolysis, andintranuclear signal transduction.

Safety Profile

Suspected carcinogen with experimental carcinogenic and tumorigenic data. When heated to decomposition it emits very toxic fumes of NO, and Cl-.

2,2',5,5'-Tetrachlorobenzidine Preparation Products And Raw materials

Raw materials

Preparation Products

Pigment Yellow 81

2,2',5,5'-Tetrachlorobenzidine Suppliers

Global( 165)Suppliers
Supplier Tel Email Country ProdList Advantage
Henan Fengda Chemical Co., Ltd 		+86-371-86557731 +86-13613820652 info@fdachem.com China 20267 58
Hebei Mojin Biotechnology Co.,Ltd 		+8613288715578 angelia@hbmojin.com China 1175 58
Hebei Ganmiao New material Technology Co., LTD 		+86-17332992504 +86-17332992504 sales8@hbganmiao.com China 300 58
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29879 58
Hubei Jusheng Technology Co.,Ltd. 		18871490254 linda@hubeijusheng.com CHINA 28172 58
Shandong chuangyingchemical Co., Ltd. 		18853181302 sale@chuangyingchem.com CHINA 5906 58
Chongqing Chemdad Co., Ltd 		+86-023-6139-8061 +86-86-13650506873 sales@chemdad.com China 39894 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49374 58
Hefei TNJ Chemical Industry Co.,Ltd. 		+86-0551-65418671 +8618949823763 sales@tnjchem.com China 34563 58
Dideu Industries Group Limited 		+86-29-89586680 +86-15129568250 1026@dideu.com China 22787 58
Supplier Advantage
Henan Fengda Chemical Co., Ltd 		58
Hebei Mojin Biotechnology Co.,Ltd 		58
Hebei Ganmiao New material Technology Co., LTD 		58
career henan chemical co 		58
Hubei Jusheng Technology Co.,Ltd. 		58
Shandong chuangyingchemical Co., Ltd. 		58
Chongqing Chemdad Co., Ltd 		58
CONIER CHEM AND PHARMA LIMITED 		58
Hefei TNJ Chemical Industry Co.,Ltd. 		58
Dideu Industries Group Limited 		58

View Lastest Price from 2,2',5,5'-Tetrachlorobenzidine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2,2',5,5'-Tetrachlorobenzidine pictures 2024-08-21 2,2',5,5'-Tetrachlorobenzidine
15721-02-5
 US $0.00 / kg 1kg 99% 50000KG/month Hebei Mojin Biotechnology Co.,Ltd
2,2',5,5'-Tetrachlorobenzidine pictures 2024-08-20 2,2',5,5'-Tetrachlorobenzidine
15721-02-5
 US $10.00-7.00 / kg 1kg 98% 20ton Hebei Ganmiao New material Technology Co., LTD
2,2',5,5'-Tetrachlorobenzidine pictures 2024-04-24 2,2',5,5'-Tetrachlorobenzidine
15721-02-5
 US $8.00-2.00 / kg 1kg 99% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd

2,2',5,5'-Tetrachlorobenzidine Spectrum

2,2',5,5'-Tetrachlorobenzidine(15721-02-5)MS2,2',5,5'-Tetrachlorobenzidine(15721-02-5)1HNMR2,2',5,5'-Tetrachlorobenzidine(15721-02-5)13CNMR2,2',5,5'-Tetrachlorobenzidine(15721-02-5)IR12,2',5,5'-Tetrachlorobenzidine(15721-02-5)IR2

15721-02-5(2,2',5,5'-Tetrachlorobenzidine)Related Search:

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Diphenylamine 2,2',5-TRICHLOROBIPHENYL 2,5-DICHLOROTOLUENE 3,3'-Dichlorobenzidine dihydrochloride 2,3',5-TRICHLOROBIPHENYL
Benzidine dihydrochloride Pigment Yellow 81 2,5-DICHLOROBIPHENYL 2,2'-dichlorobenzidine 2-CHLOROBIPHENYL
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4,4'-diamino-5,5',2,2'-tetrachlorobiphenyl 2,2,5,5-TETRACHLORO-4,4-DIAMINOBIPHENYL 2,2,5,5-TETRACHLOROBENZIDINE 98+% 2,2',5,5'-Tetrachloro-[1,1'-Biphenyl]-4,4'-diamine 2,2',5,5'-TETRACHLOROBENZIDINE 4,4'-DIAMINO-2,2',5,5'-TETRACHLOROBIPHENYL 2,2',5,5'-Tetrachlorobiphenyl-4,4'-diamine TCB Benzidine, 2,2',5,5'-tetrachloro- 2,2',5,5'-Tetrachlor OIP3 PK3 PKM1 active human 2,2’,5,5’-tetrachloro-benzidin 3,3’,6,6’-tetrachlorobenzidine 1’-biphenyl)-4,4’-diamine,2,2’,5,5’-tetrachloro-( 1’-biphenyl]-4,4’-diamine,2,2’,5,5’-tetrachloro-[ 2,2’,5,5’-tetrachloro-4,4’-diaminodiphenyl 4-(4-aminophenyl)-N,N,2,3-tetrachloroaniline [1,1'-Biphenyl]-4,4'-diamine, 2,2',5,5'-tetrachloro- 2,2',5,5'-Tetrachlorobenzidine ISO 9001：2015 REACH 2,2',5,5'-tetrachlorobenzidine 2,2',5,5'-Tetrachloro-[1,1'-biphenyl]-4,4'-diamine 2,2',5,5'-Tetrachloro-4,4'-biphenyldiamine 2,2',5,5'-Tetrachlorobenzidine in isooctane 15721-02-5 -C6H2Cl24NH22 C12H8Cl4N2 Biphenyl & Diphenyl ether Intermediates of Dyes and Pigments