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Linoleic Acid Alkyne

CAS No.
1219038-31-9
Chemical Name:
Linoleic Acid Alkyne
Synonyms
Linoleic Acid Alkyne;9(Z),12(Z)-octadecadien-17-ynoic acid;9,12-Octadecadien-17-ynoic acid, (9Z,12Z)-
CBNumber:
CB64667018
Molecular Formula:
C18H28O2
Molecular Weight:
276.41
MDL Number:
MOL File:
1219038-31-9.mol
Last updated:2023-06-08 09:03:09

Linoleic Acid Alkyne Properties

Boiling point 393.8±37.0 °C(Predicted)
Density 0.948±0.06 g/cm3(Predicted)
solubility 0.15 M Tris-HCl pH 8.5: >1 mg/ml; DMF: > 100 mg/ml; DMSO: > 100 mg/ml; Ethanol: > 100 mg/ml; PBS (pH 7.2): <100 μg/ml
pka 4.78±0.10(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS02,GHS07
Signal word  Danger
Hazard statements  H225-H319
Precautionary statements  P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P337+P313-P370+P378-P403+P235-P501
NFPA 704
3
2 0

Linoleic Acid Alkyne price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 10541 Linoleic Acid Alkyne ≥98% 1219038-31-9 100μg $55 2024-03-01 Buy
Cayman Chemical 10541 Linoleic Acid Alkyne ≥98% 1219038-31-9 500μg $220 2024-03-01 Buy
Cayman Chemical 10541 Linoleic Acid Alkyne ≥98% 1219038-31-9 1mg $358 2024-03-01 Buy
Cayman Chemical 10541 Linoleic Acid Alkyne ≥98% 1219038-31-9 5mg $1375 2024-03-01 Buy
AK Scientific 3388DF (9Z,12Z)-Octadeca-9,12-dien-17-ynoicacid 1219038-31-9 5mg $2415 2021-12-16 Buy
Product number Packaging Price Buy
10541 100μg $55 Buy
10541 500μg $220 Buy
10541 1mg $358 Buy
10541 5mg $1375 Buy
3388DF 5mg $2415 Buy

Linoleic Acid Alkyne Chemical Properties,Uses,Production

Description

Linoleic acid alkyne is an ω-alkyne derivative of linoleic acid . The ω-alkyne moiety allows Cu(I)-catalyzed cycloaddition chemistry with other molecules containing an azide group.1,2 Linoleic acid alkyne has been used in experiments focusing on the biological roles of linoleic acid.3,4 Alternatively, this modified lipid can be used to synthesize other alkyne-containing products, such as glycerophospholipids, for click chemistry.5

References

1. Gaebler, A., Penno, A., Kuerschner, L., et al. A highly sensitive protocol for microscopy of alkyne lipids and fluorescently tagged or immunostained proteins J. Lipid. Res. 57(10),1934-1947(2016).
2. Grammel, M., and Hang, H.C. Chemical reporters for biological discovery Nat. Chem. Biol. 9(8),475-484(2013).
3. Beavers, W.N., Serwa, R., Shimozu, Y., et al. ω-Alkynyl lipid surrogates for polyunsaturated fatty acids: Free radical and enzymatic oxidations J. Am. Chem. Soc. 136(32),11529-11539(2014).
4. Windsor, K., Genaro-Mattos, T.C., Kim, H.-Y.H., et al. Probing lipid-protein adduction with alkynyl surrogates: application to Smith-Lemli-Opitz syndrome J. Lipid. Res. 54(10),2842-2850(2013).
5. Milne, S.B., Tallman, K.A., Serwa, R., et al. Capture and release of alkyne-derivatized glycerophospholipids using cobalt chemistry Nat. Chem. Biol. 6(3),205-207(2010).

Linoleic Acid Alkyne Preparation Products And Raw materials

Raw materials

Preparation Products

Linoleic Acid Alkyne Suppliers

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Alfa Chemistry
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Shenzhen Regent Biochemical Technology Co., Ltd. 0755-0755-85201366 18938635012 sales@regentsciences.com China 9301 58
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SHANGHAI ZZBIO CO., LTD. 19921389125 19921389125 tech@zzbioco.com China 12065 58
Linoleic Acid Alkyne 9(Z),12(Z)-octadecadien-17-ynoic acid 9,12-Octadecadien-17-ynoic acid, (9Z,12Z)- 1219038-31-9