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MS0124

MS0124 Structure
MS0124 structure
CAS No.
1197196-63-6
Chemical Name:
MS0124
Synonyms
MS0124;4-Quinazolinamine, 6,7-dimethoxy-N-(1-methyl-4-piperidinyl)-2-(4-morpholinyl)-
CBNumber:
CB64668237
Molecular Formula:
C20H29N5O3
Molecular Weight:
387.48
MDL Number:
MOL File:
1197196-63-6.mol
Last updated:2023-07-21 08:27:59
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MS0124 Properties

Boiling point 582.6±60.0 °C(Predicted)
Density 1.232±0.06 g/cm3(Predicted)
pka 8.84±0.70(Predicted)

MS0124 Chemical Properties,Uses,Production

Description

MS0124 is a Potent and Selective Inhibitors for G9a-Like Protein (GLP) Lysine Methyltransferase. MS0124 was 34-fold more selective for GLP (IC50 =_x000D_ 13 ± 4 nM) over G9a (IC50 = 440 ± 63 nM). G9a-like protein (GLP) and G9a are highly homologous protein lysine methyltransferases (PKMTs) sharing approximately 80% sequence identity in their catalytic domains. GLP and G9a form a heterodimer complex and catalyze mono- and dimethylation of histone H3 lysine 9 and nonhistone substrates

MS0124 synthesis

110-91-8
1197196-66-9
1197196-63-6
Synthesis of MS0124 from Morpholine and 4-Quinazolinamine, 2-chloro-6,7-dimethoxy-N-(1-methyl-4-piperidinyl)-

MS0124 Preparation Products And Raw materials

Raw materials

Preparation Products

MS0124 Suppliers

Global( 7)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6313 58
Jinan Jiuli Biotechnology Co. , Ltd. 15865264761 486064515@qq.com China 3260 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 21667 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11975 58
RD International Technology Co., Limited 18024082417 market@ubiochem.com China 9268 58
Nanjing Shizhou Biology Technology Co.,Ltd 025-85560043 15850508050 cindy.huang@synzest.com China 12007 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		58
Jinan Jiuli Biotechnology Co. , Ltd. 58
TargetMol Chemicals Inc. 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
RD International Technology Co., Limited 58
Nanjing Shizhou Biology Technology Co.,Ltd 58
MS0124 4-Quinazolinamine, 6,7-dimethoxy-N-(1-methyl-4-piperidinyl)-2-(4-morpholinyl)- 1197196-63-6