ChemicalBook >> CAS DataBase List >>MS0124
MS0124
- CAS No.
- 1197196-63-6
- Chemical Name:
- MS0124
- Synonyms
- MS0124;4-Quinazolinamine, 6,7-dimethoxy-N-(1-methyl-4-piperidinyl)-2-(4-morpholinyl)-
- CBNumber:
- CB64668237
- Molecular Formula:
- C20H29N5O3
- Molecular Weight:
- 387.48
- MDL Number:
- MOL File:
- 1197196-63-6.mol
Last updated:2024-11-19 23:02:33
MS0124 Chemical Properties,Uses,Production
Description
MS0124 is a Potent and Selective Inhibitors for G9a-Like Protein (GLP) Lysine Methyltransferase. MS0124 was 34-fold more selective for GLP (IC50 =_x000D_ 13 ± 4 nM) over G9a (IC50 = 440 ± 63 nM). G9a-like protein (GLP) and G9a are highly homologous protein lysine methyltransferases (PKMTs) sharing approximately 80% sequence identity in their catalytic domains. GLP and G9a form a heterodimer complex and catalyze mono- and dimethylation of histone H3 lysine 9 and nonhistone substrates
Synthesis of MS0124 from Morpholine and 4-Quinazolinamine, 2-chloro-6,7-dimethoxy-N-(1-methyl-4-piperidinyl)-
MS0124 Preparation Products And Raw materials
Raw materials
Preparation Products
MS0124 Suppliers
Global( 8)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32165 | 58 |
HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6312 | 58 |
Shanghai SuperLan Chemcial Technique Centre | 021-2022843681 15618226720 | lucy@atkchemical.com | China | 10169 | 58 |
Jinan Jiuli Biotechnology Co. , Ltd. | 15865264761 | 486064515@qq.com | China | 3735 | 58 |
TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24647 | 58 |
Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11974 | 58 |
RD International Technology Co., Limited | 18024082417 | market@ubiochem.com | China | 9272 | 58 |
Nanjing Shizhou Biology Technology Co.,Ltd | 025-85560043 15850508050 | cindy.huang@synzest.com | China | 12005 | 58 |
MS0124
4-Quinazolinamine, 6,7-dimethoxy-N-(1-methyl-4-piperidinyl)-2-(4-morpholinyl)-
1197196-63-6