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GS 143

CAS No.
916232-21-8
Chemical Name:
GS 143
Synonyms
GS 143;4-(3-Benzyl-4-{[5-(2-fluorophenyl)furan-2-yl]methylidene}-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzoic acid;4-[4-[[5-(2-Fluorophenyl)-2-furanyl]methylene]-4,5-dihydro-5-oxo-3-(phenylmethyl)-1H-pyrazol-1-yl]benzoic acid;Benzoic acid, 4-[4-[[5-(2-fluorophenyl)-2-furanyl]methylene]-4,5-dihydro-5-oxo-3-(phenylmethyl)-1H-pyrazol-1-yl]-;E2 conjugating enzyme,inhibit,IκBα,Th2,Ubiquitin conjugating enzyme,GS143,Ubiquitin ligase,IL-4,IκB kinase,βTrCP1,Nuclear factor-kappaB,eosinophil,Ubiquitin activating enzyme,Nuclear factor-κB,I kappa B kinase,NF-κB,E3 ligating enzyme,IKK,E1 activating enzyme,anti-asthma,E1/E2/E3 Enzyme,ubiquitination,Inhibitor,airway,inflammation
CBNumber:
CB64721604
Molecular Formula:
C28H19FN2O4
Molecular Weight:
466.46
MDL Number:
MFCD30182334
MOL File:
916232-21-8.mol
Last updated:2024-07-02 08:55:14

GS 143 Properties

Boiling point 667.9±65.0 °C(Predicted)
Density 1.30±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMF:25.0(Max Conc. mg/mL);53.59(Max Conc. mM)
DMF:PBS (pH 7.2) (1:4):0.2(Max Conc. mg/mL);0.43(Max Conc. mM)
DMSO:31.38(Max Conc. mg/mL);67.28(Max Conc. mM)
form A crystalline solid
pka 4.20±0.10(Predicted)
color Pink to red

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
NFPA 704
0
2 0

GS 143 price More Price(15)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 26138 GS-143 916232-21-8 5mg $106 2024-03-01 Buy
Cayman Chemical 26138 GS-143 916232-21-8 50mg $672 2024-03-01 Buy
Cayman Chemical 26138 GS-143 916232-21-8 10mg $167 2024-03-01 Buy
Cayman Chemical 26138 GS-143 916232-21-8 25mg $388 2024-03-01 Buy
Tocris 5636 GS143 ≥98%(HPLC) 916232-21-8 10 $182 2021-12-16 Buy
Product number Packaging Price Buy
26138 5mg $106 Buy
26138 50mg $672 Buy
26138 10mg $167 Buy
26138 25mg $388 Buy
5636 10 $182 Buy

GS 143 Chemical Properties,Uses,Production

Uses

4-[4-[[5-(2-Fluorophenyl)-2-furanyl]methylene]-4,5-dihydro-5-oxo-3-(phenylmethyl)-1H-pyrazol-1-yl]-benzoic Acid blocks LPS-induced expression of inflammatory cytokines in human myelomonocytic cells.

storage

Store at +4°C

GS 143 Preparation Products And Raw materials

Raw materials

Preparation Products

GS 143 Suppliers

Global( 28)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32957 60
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32165 58
Aladdin Scientific
+1-+1(833)-552-7181 sales@aladdinsci.com United States 52924 58
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696,15000506266 15000506266 China 4512 55
Struchem Co., Ltd. 0512-0512-63009836 15365350169 helen@struchem.com China 3984 60
Shanghai Chaolan Chemical Technology Center 021-QQ:65489617 15618227136 Sales@ATKchemical.com China 7268 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6777 58
BOC Sciences -- info@bocsci.com USA 0 65
DC Chemicals 021-58447131 13564518121 sales@dcchemicals.com China 9409 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11217 58

GS 143 Spectrum

916232-21-8(GS 143)Related Search:

GS 143 4-[4-[[5-(2-Fluorophenyl)-2-furanyl]methylene]-4,5-dihydro-5-oxo-3-(phenylmethyl)-1H-pyrazol-1-yl]benzoic acid 4-(3-Benzyl-4-{[5-(2-fluorophenyl)furan-2-yl]methylidene}-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzoic acid E2 conjugating enzyme,inhibit,IκBα,Th2,Ubiquitin conjugating enzyme,GS143,Ubiquitin ligase,IL-4,IκB kinase,βTrCP1,Nuclear factor-kappaB,eosinophil,Ubiquitin activating enzyme,Nuclear factor-κB,I kappa B kinase,NF-κB,E3 ligating enzyme,IKK,E1 activating enzyme,anti-asthma,E1/E2/E3 Enzyme,ubiquitination,Inhibitor,airway,inflammation Benzoic acid, 4-[4-[[5-(2-fluorophenyl)-2-furanyl]methylene]-4,5-dihydro-5-oxo-3-(phenylmethyl)-1H-pyrazol-1-yl]- 916232-21-8