2-(1-HydroxyCyclohexyl)-2-(4-MethoxyPhenyl)Acetonitrile
- CAS No.
- 93413-76-4
- Chemical Name:
- 2-(1-HydroxyCyclohexyl)-2-(4-MethoxyPhenyl)Acetonitrile
- Synonyms
- forVenlafaxine;Venlafaxine Cyano;Venlafaxine Impurity 15;Venlafaxine Impurity 28;VENLAFAXINE CYNO IMPURITY;Venlafaxine Cyano Impurity;Intermediate of Venlafaxine;Venlafaxine Nitrile Impurity;1-[Cyano-(4-Methoxyphenyl)Meth;D,L-VENLAFAXINE, HYDROCHLORIDE int
- CBNumber:
- CB6476117
- Molecular Formula:
- C15H19NO2
- Molecular Weight:
- 245.32
- MDL Number:
- MFCD06658142
- MOL File:
- 93413-76-4.mol
- MSDS File:
- SDS
Melting point | 121-123°C |
---|---|
Boiling point | 410.1±25.0 °C(Predicted) |
Density | 1.142±0.06 g/cm3(Predicted) |
storage temp. | Sealed in dry,2-8°C |
solubility | soluble in Methanol |
form | powder to crystal |
pka | 13.80±0.20(Predicted) |
color | White to Almost white |
CAS DataBase Reference | 93413-76-4(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302+H312+H332-H315-H319 |
Precautionary statements | P261-P264-P270-P271-P280-P301+P312+P330-P302+P352+P312+P362+P364-P304+P340+P312-P305+P351+P338+P337+P313-P501 |
HS Code | 2926.90.4850 |
2-(1-HydroxyCyclohexyl)-2-(4-MethoxyPhenyl)Acetonitrile price More Price(17)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
TCI Chemical | H1303 | (1-Hydroxycyclohexyl)(4-methoxyphenyl)acetonitrile >98.0%(HPLC)(N) | 93413-76-4 | 1g | $116 | 2023-06-20 | Buy |
TCI Chemical | H1303 | (1-Hydroxycyclohexyl)(4-methoxyphenyl)acetonitrile >98.0%(HPLC)(N) | 93413-76-4 | 5g | $349 | 2023-06-20 | Buy |
Biosynth Carbosynth | FC20603 | 1-[Cyano-(4-methoxyphenyl)methyl]cyclohexanol | 93413-76-4 | 25mg | $254.5 | 2021-12-16 | Buy |
Biosynth Carbosynth | FC20603 | 1-[Cyano-(4-methoxyphenyl)methyl]cyclohexanol | 93413-76-4 | 10mg | $139.8 | 2021-12-16 | Buy |
Biosynth Carbosynth | FC20603 | 1-[Cyano-(4-methoxyphenyl)methyl]cyclohexanol | 93413-76-4 | 50mg | $462 | 2021-12-16 | Buy |
2-(1-HydroxyCyclohexyl)-2-(4-MethoxyPhenyl)Acetonitrile Chemical Properties,Uses,Production
Synthesis
A mixture of p-methoxyphenylacetonitrile 36 (100 g, 0.68 mol), 10%
aqueous NaOH solution (100 ml, 0.25 mol) and TBAHSO4 (5 g, 0.014
mol) was stirred at room temperature for 30 minutes. A dark red colour
appeared. To this was added cyclohexanone 34 (67 g, 0.680 mol) in
small portions at 0 ºC, with vigorous stirring, in such a way that
temperature should not rise above 10 ºC. A white solid was formed
within 30 minutes to one hour. The solid was crushed and the reaction mixture was further
stirred vigorously at room temperature for one more hour. The solid was filtered, washed
with water till neutral to pH paper and air-dried. Crystallization from ethyl acetatepetroleum ether (500:350, v/v) gave a bright white solid (161.66 g).
Chemical Properties
White Powder
Uses
An intermediate in the synthesis of N,O-Didesmethylvenlafaxine, a metabolite of Venlafaxine
2-(1-HydroxyCyclohexyl)-2-(4-MethoxyPhenyl)Acetonitrile Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29798 | 60 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 18628 | 58 |
Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9284 | 55 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29888 | 58 |
Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10311 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
Jinan Finer Chemical Co., Ltd | +86-531-88989536 +86-15508631887 | sales@finerchem.com | China | 2966 | 58 |
Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14335 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39916 | 58 |
Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
View Lastest Price from 2-(1-HydroxyCyclohexyl)-2-(4-MethoxyPhenyl)Acetonitrile manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2022-09-14 | 2-(1-HydroxyCyclohexyl)-2-(4-MethoxyPhenyl)Acetonitrile
93413-76-4
|
US $0.00-0.00 / KG | 1KG | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. | ||
2019-07-06 | 1-[Cyano-(p-methoxyphenyl)methyl]cyclohexanol
93413-76-4
|
US $8.80 / KG | 1KG | 97%-99% | 100kg | Career Henan Chemical Co |
- 2-(1-HydroxyCyclohexyl)-2-(4-MethoxyPhenyl)Acetonitrile
93413-76-4
- US $0.00-0.00 / KG
- 98%
- Henan Aochuang Chemical Co.,Ltd.
- 1-[Cyano-(p-methoxyphenyl)methyl]cyclohexanol
93413-76-4
- US $8.80 / KG
- 97%-99%
- Career Henan Chemical Co