3-chloro-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide

3-chloro-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide structure

CAS No.: 627484-44-0

Chemical Name:: 3-chloro-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide

Synonyms: 3-Chloro-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide

CBNumber:: CB64765437

Molecular Formula:: C12H10ClF3N2O2

Molecular Weight:: 306.6682096

MDL Number:

MOL File:: 627484-44-0.mol

Last updated:2023-05-15 10:43:56

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3-chloro-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide Properties

solubility	Chloroform (Slightly), Methanol (Slightly)
form	Solid
color	White to Off-White

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302
Precautionary statements	P264-P270-P301+P312-P330-P501

3-chloro-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide Chemical Properties,Uses,Production

Uses

3-Chloro-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide is a useful intermediate in the preparation of bicalutamide, a therapeutically important anti-??androgen used in the treatment of hormone-??sensitive cancers. A bicalutamide related compound.

3-chloro-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide Preparation Products And Raw materials

Raw materials

Benzonitrile, 4-isocyanato-2-(trifluoroMethyl)- 2-Methyloxirane-2-carboxylic acid

Preparation Products

N-[4-Cyano-3-(trifluoromethyl)phenyl]methacrylamide epoxide

3-Chloro-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide 627484-44-0