Bromo-PEG1-azide
- CAS No.
- 1144106-65-9
- Chemical Name:
- Bromo-PEG1-azide
- Synonyms
- Bromo-PEG1-azide;Bromo-PEG1-C2-azide;Bromo-PEG1-azide, Bromo-PEG1-N3;1-azido-2-(2-bromoethoxy)ethane;1-Azido-2-(2-bromoethoxy)ethane/Bromo-PEG1-C2-azide;inhibit,PROTAC Linkers,Bromo-PEG-1-C2-azide,BromoPEG1C2azide,Inhibitor,Bromo PEG1 C2 azide
- CBNumber:
- CB64849564
- Molecular Formula:
- C4H8BrN3O
- Molecular Weight:
- 194.03
- MDL Number:
- MFCD24454187
- MOL File:
- 1144106-65-9.mol
Bromo-PEG1-azide Chemical Properties,Uses,Production
Description
Bromo-PEG1-azide is a bifunctional PEG linker with a bromide (Br)group and an azide(N3) group. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The bromide (Br) is a good leaving group for nucleophilic substitution reactions.
Uses
Bromo-PEG1-C2-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Bromo-PEG1-C2-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Bromo-PEG1-azide Preparation Products And Raw materials
Raw materials
Preparation Products
Bromo-PEG1-azide Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32222 | 58 |
| Alfa Chemistry | Info@alfa-chemistry.com | United States | 24072 | 58 | |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42056 | 58 |
| Xian confluore Biological Technology Co., Ltd. | +86-15680926068 +86-15680926068 | 1924344760@confluore.cn | China | 2996 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52924 | 58 | |
| Sichuan Wei Keqi Biological Technology Co., Ltd. | 028-81700200 18116577057 | 3003855609@qq.com | China | 7787 | 56 |
| Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd | 0431-0431-80514535 19917294565 | et@chemextension.com | China | 3962 | 55 |
| Borenpharm Co., Ltd | 027-65563561 | sales@borenpharm.com | China | 1245 | 55 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9803 | 58 |
| Amatek Scientific Co. Ltd. | 0512-56316828 | info@amateksci.com | China | 28803 | 58 |
View Lastest Price from Bromo-PEG1-azide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-19 | Bromo-PEG1-C2-azide
1144106-65-9
|
US $39.00-95.00 / mg | 98.98% | 10g | TargetMol Chemicals Inc. | ||
 |
2024-03-24 | Azido-PEG1-Br
1144106-65-9
|
US $0.00 / g | 1g | >98.00% | 1g | Xian confluore Biological Technology Co., Ltd. |
-
- Bromo-PEG1-C2-azide
1144106-65-9
- US $39.00-95.00 / mg
- 98.98%
- TargetMol Chemicals Inc.
-
- Azido-PEG1-Br
1144106-65-9
- US $0.00 / g
- >98.00%
- Xian confluore Biological Technology Co., Ltd.