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ChemicalBook >> CAS DataBase List >>5-(2,6-Dichloro-5-fluoro-3-pyridinyl)-3-phenyl-2-(trifluoromethyl)-pyrazolo[1,5-a]pyrimidin-7(4H)-one

5-(2,6-Dichloro-5-fluoro-3-pyridinyl)-3-phenyl-2-(trifluoromethyl)-pyrazolo[1,5-a]pyrimidin-7(4H)-one

5-(2,6-Dichloro-5-fluoro-3-pyridinyl)-3-phenyl-2-(trifluoromethyl)-pyrazolo[1,5-a]pyrimidin-7(4H)-one Structure
5-(2,6-Dichloro-5-fluoro-3-pyridinyl)-3-phenyl-2-(trifluoromethyl)-pyrazolo[1,5-a]pyrimidin-7(4H)-one structure
CAS No.
1259536-62-3
Chemical Name:
5-(2,6-Dichloro-5-fluoro-3-pyridinyl)-3-phenyl-2-(trifluoromethyl)-pyrazolo[1,5-a]pyrimidin-7(4H)-one
Synonyms
QO 58;5-(2,6-Dichloro-5-fluoro-3-pyridinyl)-3-phenyl-2-(trifluoromethyl)-pyrazolo[1,5-a]pyrimidin-7(4H)-one;Pyrazolo[1,5-a]pyrimidin-7(4H)-one, 5-(2,6-dichloro-5-fluoro-3-pyridinyl)-3-phenyl-2-(trifluoromethyl)-
CBNumber:
CB64902810
Molecular Formula:
C18H8Cl2F4N4O
Molecular Weight:
443.18
MDL Number:
MFCD30182255
MOL File:
1259536-62-3.mol
Last updated:2024-10-23 13:36:13
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5-(2,6-Dichloro-5-fluoro-3-pyridinyl)-3-phenyl-2-(trifluoromethyl)-pyrazolo[1,5-a]pyrimidin-7(4H)-one Properties

Melting point >300 °C
Boiling point 568.5±60.0 °C(Predicted)
Density 1.66±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Soluble in DMSO
pka -2.49±0.10(Predicted)
form Solid
color White to off-white

5-(2,6-Dichloro-5-fluoro-3-pyridinyl)-3-phenyl-2-(trifluoromethyl)-pyrazolo[1,5-a]pyrimidin-7(4H)-one price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Tocris 5083 QO58 ≥98%(HPLC) 1259536-62-3 10 $201 2021-12-16 Buy
Tocris 5083 QO58 ≥98%(HPLC) 1259536-62-3 50 $844 2021-12-16 Buy
Product number Packaging Price Buy
5083 10 $201 Buy
5083 50 $844 Buy

5-(2,6-Dichloro-5-fluoro-3-pyridinyl)-3-phenyl-2-(trifluoromethyl)-pyrazolo[1,5-a]pyrimidin-7(4H)-one Chemical Properties,Uses,Production

Uses

QO 58 is a novel potassium channel opener, which modulates Kv7/M channel function.

storage

Store at +4°C

5-(2,6-Dichloro-5-fluoro-3-pyridinyl)-3-phenyl-2-(trifluoromethyl)-pyrazolo[1,5-a]pyrimidin-7(4H)-one synthesis

96568-04-6
62649-36-9
1259536-62-3
Synthesis of 5-(2,6-Dichloro-5-fluoro-3-pyridinyl)-3-phenyl-2-(trifluoromethyl)-pyrazolo[1,5-a]pyrimidin-7(4H)-one from Ethyl 2,6-dichloro-5-fluoro-pyridine-3-acetoacetate and 4-phenyl-5-(trifluoromethyl)-1~{H}-pyrazol-3-amine

5-(2,6-Dichloro-5-fluoro-3-pyridinyl)-3-phenyl-2-(trifluoromethyl)-pyrazolo[1,5-a]pyrimidin-7(4H)-one Preparation Products And Raw materials

Raw materials

Preparation Products

5-(2,6-Dichloro-5-fluoro-3-pyridinyl)-3-phenyl-2-(trifluoromethyl)-pyrazolo[1,5-a]pyrimidin-7(4H)-one Suppliers

Global( 18)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32161 58
Nantong HI-FUTURE Biology Co., Ltd. 		+undefined18051384581 sales@chemhifuture.com China 3135 58
TargetMol Chemicals Inc. 		support@targetmol.com United States 38631 58
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 52924 58
Chengdu Chuangkecheng Biological Technology Co., Ltd. 028-028-0000000 13008177686 sales@ckcbiotech.com China 791 55
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6777 58
BOC Sciences -- info@bocsci.com USA 0 65
Jinan Jiuli Biotechnology Co. , Ltd. 15865264761 486064515@qq.com China 4542 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24644 58
Shanghai Tachizaki Biomedical Research Center 18014399201 sales@chemlab-tachizaki.com China 2613 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Nantong HI-FUTURE Biology Co., Ltd. 		58
TargetMol Chemicals Inc. 		58
Aladdin Scientific 		58
Chengdu Chuangkecheng Biological Technology Co., Ltd. 55
Shanghai Hongye Biotechnology Co. Ltd 58
BOC Sciences 65
Jinan Jiuli Biotechnology Co. , Ltd. 58
TargetMol Chemicals Inc. 58
Shanghai Tachizaki Biomedical Research Center 58

View Lastest Price from 5-(2,6-Dichloro-5-fluoro-3-pyridinyl)-3-phenyl-2-(trifluoromethyl)-pyrazolo[1,5-a]pyrimidin-7(4H)-one manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
QO-58 pictures 2024-10-24 QO-58
1259536-62-3
 US $82.00 / mg 10g TargetMol Chemicals Inc.
  • QO-58 pictures
  • QO-58
    1259536-62-3
  • US $82.00 / mg
  • TargetMol Chemicals Inc.
5-(2,6-Dichloro-5-fluoro-3-pyridinyl)-3-phenyl-2-(trifluoromethyl)-pyrazolo[1,5-a]pyrimidin-7(4H)-one QO 58 Pyrazolo[1,5-a]pyrimidin-7(4H)-one, 5-(2,6-dichloro-5-fluoro-3-pyridinyl)-3-phenyl-2-(trifluoromethyl)- 1259536-62-3