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Thalidomide-NH-C4-NH2 TFA

CAS No.
2093387-50-7
Chemical Name:
Thalidomide-NH-C4-NH2 TFA
Synonyms
Poma-C4-NH2 TFA;Pomalidomide-C4-NH2 TFA;halidomide-NH-C4-NH2TFA;Thalidomide-NH-C4-NH2 TFA;Pomalidomide Related Compound 10 Triflate;4-((4-aminobutyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione 2,2,2-trifluoroacetate
CBNumber:
CB66127051
Molecular Formula:
C19H21F3N4O6
Molecular Weight:
458.39
MDL Number:
MFCD32903491
MOL File:
2093387-50-7.mol
Last updated:2024-04-01 13:48:23

Thalidomide-NH-C4-NH2 TFA Chemical Properties,Uses,Production

Biological Activity

Thalidomide-NH-C4-NH2 TFA (compound 29c) is an E3 ligase ligand-linker conjugate, and incorporates the Thalidomide based cereblon ligand and a linker. Thalidomide-NH-C4-NH2 TFA is used in PROTAC BRD2/BRD4 degrader-1 . PROTAC BRD2/BRD4 degrader-1 is a potent and selective BET protein BRD4 and BRD2 degrader[1].

References

[1]. Jiang F, et al. Discovery of novel small molecule induced selective degradation of the bromodomain and extra-terminal (BET) bromodomain protein BRD4 and BRD2 with cellular potencies. Bioorg Med Chem. 2020 Jan 1;28(1):115181.

Thalidomide-NH-C4-NH2 TFA Preparation Products And Raw materials

Raw materials

Preparation Products

Thalidomide-NH-C4-NH2 TFA Suppliers

Global( 15)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32165 58
Jilin Chinese Academy of Sciences-yanshen Technology
+undefined18143011203 info@chemextension.com China 42056 58
Xian confluore Biological Technology Co., Ltd.
+86-15680926068 +86-15680926068 1924344760@confluore.cn China 2995 58
Sichuan Wei Keqi Biological Technology Co., Ltd. 028-81700200 18116577057 3003855609@qq.com China 7887 56
Xi'an Confluore Biological Technology Co., Ltd. +86-156-80926068 +86-15680926068 1924344760@qq.com China 4824 58
Jilin Province Woda Biotechnology Co., Ltd. 13504435624 1927928688@qq.com China 1388 58
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd 0431-80514535 19917294565 caoy@chemextension.com China 4756 58
Hunan Zengda Biological Technology Co., LTD 18711085600 1652923704@qq.com China 4582 58
Changzhou Bojia Biomedical Technology Co., Ltd. 2122619822 czbjpharma@126.com China 18478 58
Chengdu Yuxin Technology Co., Ltd. 13558691827 yuxinpharma@126.com China 95 58

View Lastest Price from Thalidomide-NH-C4-NH2 TFA manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Pomalidomide-C4-NH2 TFA pictures 2024-04-02 Pomalidomide-C4-NH2 TFA
2093387-50-7
US $0.00 / mg 100mg >99.00% 100mg Xian confluore Biological Technology Co., Ltd.
Thalidomide-NH-C4-NH2 TFA Pomalidomide Related Compound 10 Triflate 4-((4-aminobutyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione 2,2,2-trifluoroacetate halidomide-NH-C4-NH2TFA Pomalidomide-C4-NH2 TFA Poma-C4-NH2 TFA 2093387-50-7