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2'-FLUORO AEA

2'-FLUORO AEA Structure
2'-FLUORO AEA structure
CAS No.
166100-37-4
Chemical Name:
2'-FLUORO AEA
Synonyms
AFEA;2'-FLUORO AEA;AEA, 2'-FLUORO;-fluoroethylamide;Arachidonyl-2’2'-FLUORO ANANDAMIDE;Arachidonoyl-2’ANANDAMIDE, 2'-FLUORO;FLUOROETHYLEICOSATETRAENAMIDE;Arachidonyl-2-fluoroethylamide
CBNumber:
CB6666556
Molecular Formula:
C22H36FNO
Molecular Weight:
349.53
MDL Number:
MFCD02259376
MOL File:
166100-37-4.mol
Last updated:2023-07-14 17:31:21
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2'-FLUORO AEA Properties

Boiling point 496.0±45.0 °C(Predicted)
Density 0.925±0.06 g/cm3(Predicted)
solubility DMF: 10 mg/ml; DMSO: 7 mg/ml; Ethanol: 15 mg/ml; Ethanol:PBS (1:1): 8 mg/ml
pka 15.24±0.46(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS02,GHS07
Signal word  Danger
Hazard statements  H225-H319
Precautionary statements  P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P337+P313-P370+P378-P403+P235-P501
NFPA 704
3
2 0

2'-FLUORO AEA price More Price(7)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 90054 Arachidonoyl-2'-Fluoroethylamide ≥98% 166100-37-4 5mg $48 2024-03-01 Buy
Cayman Chemical 90054 Arachidonoyl-2'-Fluoroethylamide ≥98% 166100-37-4 10mg $89 2024-03-01 Buy
Cayman Chemical 90054 Arachidonoyl-2'-Fluoroethylamide ≥98% 166100-37-4 50mg $371 2024-03-01 Buy
Cayman Chemical 90054 Arachidonoyl-2'-Fluoroethylamide ≥98% 166100-37-4 100mg $646 2024-03-01 Buy
American Custom Chemicals Corporation LIP0005000 2'-FLUORO AEA 95.00% 166100-37-4 5MG $503.79 2021-12-16 Buy
Product number Packaging Price Buy
90054 5mg $48 Buy
90054 10mg $89 Buy
90054 50mg $371 Buy
90054 100mg $646 Buy
LIP0005000 5MG $503.79 Buy

2'-FLUORO AEA Chemical Properties,Uses,Production

Description

Arachidonoyl-2'-fluoroethylamide (2-fluoro AEA) is an analog of anandamide in which the alcohol of the ethanolamide group has been removed and replaced with a fluorine atom. This substitution adds considerably increased binding affinity for the CB1 receptor (Kis = 26.7 and 908 nM for CB1 and CB2, respectively). It also contributes additional selectivity, in that binding to CB2 is decreased relative to AEA.1 However, the in vivo activity of 2-fluoro AEA is enhanced much less than the binding affinity, because the analog remains a good substrate for FAAH and is rapidly hydrolyzed by this enzyme.

Uses

Arachidonoyl-2'-fluoroethylamide is a CB1 receptor agonist and an analog of Anandamide (A637220), which is an endogenous cannabinoid and TRPV1 receptor agonist.

References

1. Lin, S., Khanolkar, A.D., Fan, P., et al. Novel analogues of arachidonylethanolamide (anandamide): Affinities for the CB1 and CB2 cannabinoid receptors and metabolic stability J. Med. Chem. 41(27),5353-5361(1998).

2'-FLUORO AEA Preparation Products And Raw materials

Raw materials

Preparation Products

2'-FLUORO AEA Suppliers

Global( 13)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
BOC Sciences -- info@bocsci.com USA 0 65
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
Energy Chemical 021-58432009 400-005-6266 marketing1@energy-chemical.com China 44843 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8141 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11975 58
SHANGHAI ZZBIO CO., LTD. 15102117276 19921389125 tech@zzbioco.com China 12064 58
Supplier Advantage
Shanghai Hongye Biotechnology Co. Ltd 58
BOC Sciences 65
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
Energy Chemical 58
MedBioPharmaceutical Technology Inc 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
SHANGHAI ZZBIO CO., LTD. 58

166100-37-4(2'-FLUORO AEA)Related Search:

ANANDAMIDE O-689 2'-FLUORO AEA
FLUOROETHYLEICOSATETRAENAMIDE ARACHIDONOYL 2'-FLUOROETHYLAMIDE AFEA AEA, 2'-FLUORO ANANDAMIDE, 2'-FLUORO 2'-FLUORO AEA 2'-FLUORO ANANDAMIDE N-(2-FLUOROETHYL)-5Z,8Z,11Z,14Z-EICOSATETRAENAMIDE Arachidonyl-2-fluoroethylamide Arachidonoyl-2&rsquo 5,8,11,14-Eicosatetraenamide, N-(2-fluoroethyl)-, (5Z,8Z,11Z,14Z)- Arachidonyl-2&rsquo -fluoroethylamide Arachidonoyl-2'-Fluoroethylamide 166100-37-4