Sodium gualenate
- CAS No.
- 6223-35-4
- Chemical Name:
- Sodium gualenate
- Synonyms
- Guai;SODIUM GUAIAZULENE SULFONATE;sodium gualenate;3-Sulfonate sodium salt;Azulene sulfonate sodium;Sodium guazulene sulfonate;Guaiazulenesulfonate sodium;guaiazulene / azulene powder;Sodium azulene sulphonate, 98%;Sodium gualenate, 10 mM in DMSO
- CBNumber:
- CB6688455
- Molecular Formula:
- C15H17NaO3S
- Molecular Weight:
- 300.35
- MDL Number:
- MFCD00866167
- MOL File:
- 6223-35-4.mol
- MSDS File:
- SDS
| Melting point | 98°C(lit.) |
|---|---|
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | DMSO : 30 mg/mL (99.88 mM) |
| form | powder to crystaline |
| color | Blue to Dark blue |
| Merck | 14,4554 |
| EWG's Food Scores | 1 |
| FDA UNII | 19WSH095WP |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
| RTECS | CO4826000 |
| HS Code | 2908.99.1500 |
Sodium gualenate price More Price(20)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | S0976 | Sodium 7-Isopropyl-1,4-dimethylazulene-3-sulfonate >98.0%(HPLC)(T) | 6223-35-4 | 1g | $42 | 2024-03-01 | Buy |
| TCI Chemical | S0976 | Sodium 7-Isopropyl-1,4-dimethylazulene-3-sulfonate >98.0%(HPLC)(T) | 6223-35-4 | 5g | $164 | 2024-03-01 | Buy |
| AK Scientific | J90078 | Sodium 7-Isopropyl-1,4-dimethylazulene-3-sulfonate | 6223-35-4 | 250mg | $72 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0028141 | 1,4-DIMETHYL-7-ISOPROPYLAZULENE-3-SULFONATE SODIUM SALT 95.00% | 6223-35-4 | 1G | $685.21 | 2021-12-16 | Buy |
| Chem-Impex | 38267 | Sodiumgualenate,98%(HPLC) 98%(HPLC) | 6223-35-4 | 5G | $720.16 | 2021-12-16 | Buy |
Sodium gualenate Chemical Properties,Uses,Production
Description
Sodium gualenate is unstable, it will decompose under light, air oxidation and high temperature environment, and it is easy to remove the sulfonic acid group. According to existing reports, it is common for sodium azulene sulfonate to contain half or one crystal water.
Uses
Sodium gualenate is an active ingredient of chamomile flowers, which has strong anti-pepsin, anti-inflammatory, antibacterial, anti-allergic, and promotion of mucosal metabolism. It is mainly used to study duodenal ulcer, gastric ulcer and gastritis.
Mechanism of action
Sodium gualenate inhibits the release of histamine from inflammatory cells through local direct action; increases the synthesis of prostaglandin E2 in the mucosa, promotes granulation formation and epithelial cell regeneration; and can reduce the activity of pepsin.
Uses
Sodium gualenate (Guaiazulenesulfonate sodium) is a hydrophilic derivative of guaiazulene with excellent anti-inflammatory and wound-healing effects mainly used for the treatment of duodenal ulcer, gastric ulcer and gastritis.
in vivo
Sodium gualenate has been frequently used for the treatment of human gastritis. Cytoprotection is defined as the main mechanism of Sodium gualenate to protect the mucosa of the stomach and the antipeptic actions in vivo have also been shown[2].
References
[1] Nakamichi K, et al. Stabilization of sodium guaiazulene sulfonate in granules for tableting prepared using a twin-screw extruder. Eur J Pharm Biopharm. 2003 Nov;56(3):347-54. DOI:10.1016/s0939-6411(03)00100-0
[2] Cao T, et al. Synthesis and Biological Evaluation of 3, 8-dimethyl-5-isopropylazulene Derivatives as Anti-gastric Ulcer Agent. Chem Biol Drug Des. 2016 Aug;88(2):264-71. DOI:10.1111/cbdd.12753
Sodium gualenate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531157085 | abby@chuanghaibio.com | China | 8808 | 58 |
| Hebei Mujin Biotechnology Co.,Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12809 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8617531153977 | allison@yan-xi.com | China | 5854 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5868 | 58 |
| Sinoway Industrial co., ltd. | 0592-5800732; +8613806035118 | xie@china-sinoway.com | China | 987 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | mina@chuanghaibio.com | China | 18137 | 58 |
| Hebei Kingfiner Technology Development Co.Ltd | +86-15532196582 +86-15373005021 | lisa@kingfinertech.com | China | 3005 | 58 |
| Hebei Mujin Biotechnology Co.,Ltd | +8613288715578 | angelia@hbmojin.com | China | 750 | 58 |
| Hebei Zhuanglai Chemical Trading Co Ltd | +86-16264648883 +86-16264648883 | niki@zlchemi.com | China | 7245 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29730 | 60 |
View Lastest Price from Sodium gualenate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-04-24 | Sodium gualenate
6223-35-4
|
US $0.00-0.00 / Kg/Drum | 1KG | 98%-102% | 100KG | WUHAN FORTUNA CHEMICAL CO., LTD | |
 |
2025-04-24 | Sodium gualenate
6223-35-4
|
US $10.00 / kg | 1kg | 99% | 20 ton | Hebei Zhuanglai Chemical Trading Co Ltd | |
 |
2025-04-23 | Sodium Azulene Sulfonate
6223-35-4
|
US $0.00-0.00 / KG | 1KG | 98.5% up /JP/PMDA preparation | 20 tons | Sinoway Industrial co., ltd. |
-
- Sodium gualenate
6223-35-4
- US $0.00-0.00 / Kg/Drum
- 98%-102%
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- Sodium gualenate
6223-35-4
- US $10.00 / kg
- 99%
- Hebei Zhuanglai Chemical Trading Co Ltd
-
- Sodium Azulene Sulfonate
6223-35-4
- US $0.00-0.00 / KG
- 98.5% up /JP/PMDA preparation
- Sinoway Industrial co., ltd.