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POBN

CAS No.
66893-81-0
Chemical Name:
POBN
Synonyms
POBN;Butylpyridyloxidenitrone;-(4-pyridyl-1-oxide)nitrone;PYRIDYLOXIDE t-BUTYLNITRONE;N-tert-Butyl-α4-Pyridyl-1-oxide-tert-butyl Nitrone;A-(4-PYRIDYL-N-OXIDE-N-TERT-BUTYLNITRONE;N-TERT-BUTYL-A-(4-PYRIDYL)NITRONEN-OXIDE;N-tert-Butyl-α-(4-pyridyl-1-oxide)nitrone;α-(4-pyridyl n-oxide)-n-tert-butylnitrone
CBNumber:
CB6702751
Molecular Formula:
C10H14N2O2
Molecular Weight:
194.23
MDL Number:
MFCD00041022
MOL File:
66893-81-0.mol
MSDS File:
SDS
Last updated:2023-05-18 11:31:16

POBN Properties

Melting point 183-185 °C(lit.)
Boiling point 330.68°C (rough estimate)
Density 1.1444 (rough estimate)
refractive index 1.5000 (estimate)
storage temp. room temp
solubility water: soluble10mg/mL, clear, colorless to faintly yellow
form White to off-white or colorless crystalline solid.
pka 0.76±0.53(Predicted)
color White to Light yellow
BRN 1453764
FDA UNII 2140SM8Q5O

SAFETY

Risk and Safety Statements

Safety Statements  22-24/25
WGK Germany  3
HS Code  29333999

POBN price More Price(16)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 215430 α-(4-Pyridyl N-oxide)-N-tert-butylnitrone 99% 66893-81-0 1g $625 2024-03-01 Buy
Sigma-Aldrich P9271 α-(4-Pyridyl N-oxide)-N-tert-butylnitrone ~95% 66893-81-0 1g $62 2023-06-20 Buy
TCI Chemical B1735 N-tert-Butyl-alpha-(4-pyridyl-1-oxide)nitrone >98.0%(HPLC)(T) 66893-81-0 1g $224 2024-03-01 Buy
TCI Chemical B1735 N-tert-Butyl-alpha-(4-pyridyl-1-oxide)nitrone >98.0%(HPLC)(T) 66893-81-0 5g $673 2024-03-01 Buy
Cayman Chemical 20623 POBN ≥98% 66893-81-0 100mg $40 2024-03-01 Buy
Product number Packaging Price Buy
215430 1g $625 Buy
P9271 1g $62 Buy
B1735 1g $224 Buy
B1735 5g $673 Buy
20623 100mg $40 Buy

POBN Chemical Properties,Uses,Production

Chemical Properties

white to pale yellow crystalline powder

Uses

POBN is a cell permeable hydrophilic spin trap for in vitro studies. It is a water soluble analog of PBN with low paramagnetic impurities and does not require any further purification. POBN has also also been used in studies of DNA methylation, iron-mediated polyunsaturated fatty acid peroxidation, and free-radical formation by Alzheimer β-amyloid peptide.

Uses

Spin trap reagent used to measure ethanol oxidation to 1-hydroxyethyl radical (HER) which can bind to protein. Has also been used in studies of DNA methylation, iron-mediated polyunsaturated fatty acid peroxidation, and free-radical formation by Alzheimer β-amyloid peptide. The formation of hydroxyl radical in chondrocytes and cartilage has been detected using POBN.

POBN Preparation Products And Raw materials

Raw materials

Preparation Products

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α-(4-Pyridyl N-oxide)-N-tert-butylnitrone,N-(4-Pyridylmethylene)-tert-butylamine N,N′-dioxide, N-tert-Butyl-α-(4-pyridyl)nitrone N′-oxide, POBN alpha-(4-Pyridyl 1-oxide)-N-tert-butyl-nitrone, 99% 100MG N-tert-Butyl-α-(4-pyridyl)nitrone Nμ-oxide POBN, N-tert-Butyl-α-(4-pyridyl)nitrone Nμ-oxide, N-(4-Pyridylmethylene)-tert-butylamine N,Nμ-dioxide 2-Methyl-N-[(pyridine 1-oxide)-4-ylmethylene]-2-propanamine oxide 4-Pyridyl-1-oxide-tert-butyl Nitrone N-[(Pyridine 1-oxide)-4-ylmethylene]-tert-butylamineN-oxide N-[[(Pyridine-1-oxide)-4-yl]methylene]-1,1-dimethylethanamine-N-oxide N-tert-Butyl-α-(4-pyridyl-1-oxide)nitrone alpha-(4-Pyridyl 1-oxide)-N-tert-butyl-nitrone,99% N-tert-Butyl-alpha-(4-pyridyl)nitrone N'-Oxide POBN N-(4-Pyridylmethylene)-tert-butylamine N,N'-Dioxide alpha-(4-Pyridyl N-Oxide)-N-tert-butylnitrone alpha-(4-Pyridyl N-oxide)-N-tert-butylnitrone ~95% alpha-(4-Pyridyl N-oxide)-N-tert-butylnitrone 99% -(4-pyridyl-1-oxide)nitrone N-tert-Butyl-&alpha (Z)-2-Methyl-N-((1-oxidopyridin-4-yl)methylene)propan-2-amine oxide Dimethylaminoparthenolide/ Tert-Butyl-[(1-Oxido-4-Pyridylidene)Methyl]-Oxo-Ammonium N-(4-PYRIDYLMETHYLENE)-TERT-BUTYLAMINE N,N'-DIOXIDE N-TERT-BUTYL-ALPHA-(4-PYRIDYL-1-OXIDE)NITRONE N-TERT-BUTYL-ALPHA-(4-PYRIDYL)-NITRONE N'-OXIDE POBN ALPHA-(4-PYRIDYL-1-OXIDE)-N-T-BUTYLNITRONE ALPHA-(4-PYRIDYL 1-OXIDE)-N-TERT-BUTYLNITRONE ALPHA-(4-PYRIDYL N-OXIDE)-N-TERT-BUTYLNITRONE Butylpyridyloxidenitrone N-tert-Butyl-alpha-(4-pyridyl-1-oxide)nitrone [spin trapping 1,1-dimethyl-N-(4-pyridylmethylene)ethylamine N,N'-dioxide A-(4-PYRIDYL-N-OXIDE-N-TERT-BUTYLNITRONE α-(4-pyridyl n-oxide)-n-tert-butylnitrone N-TERT-BUTYL-A-(4-PYRIDYL)NITRONEN-OXIDE N-TERT-BUTYL-ALPHA-(4-PYRIDYL-1-OXIDE)NITRONE [SPIN TRAPPING REAGENT] N-tert-Butyl-alpha-(4-pyridyl-1-oxide)nitrone > 2-Propanamine, 2-methyl-N-[(1-oxido-4-pyridinyl)methylene]-, N-oxide ert-butyl-[(1-oxidopyridin-4-ylidene)methyl]-oxoazanium PYRIDYLOXIDE t-BUTYLNITRONE N-tert-Butyl-α-(4-pyridyl-1-oxide)nitrone α-(4-Pyridyl N-oxide)-N-tert-butylnitrone 66893-81-0 Building Blocks C9 to C46 Spin Trapping Reagents ESR Spectrometry Heterocyclic Building Blocks Pyridines Analytical Chemistry ESR Spectrometry Spin Trapping Reagents Analytical Reagents Analytical/Chromatography Building Blocks C10 Chemical Synthesis Electron Spin Resonance (ESR/EPR) Spectroscopy Heterocyclic Building Blocks Pyridines Spectroscopy