ChemicalBook >> CAS DataBase List >>N-Benzylpiperidine-4-carboxaldehyde
N-Benzylpiperidine-4-carboxaldehyde
- CAS No.
- 22065-85-6
- Chemical Name:
- N-Benzylpiperidine-4-carboxaldehyde
- Synonyms
- Benzylpiperidine-4-carboxaldehyde;1-Benzylpiperidine-4-carboxaldehyde;N-Benzyl-4-Piperidinecarboxaldehyde95%;N-Benzylpiperidine-4-carboxaldehyde 95%;1-(Phenylmethyl)-4-piperidinecarbaldehyde;1-(Phenylmethyl)-4-piperidinecarboxaldehyde;1-Benzyl-4-piperidinecarboxaldehyde,1-Benzyl-4-formylpiperidine;1-Benzyl-4-formylpiperidine, [(4-Formylpiperidin-1-yl)methyl]benzene;ZERO/005913;RSYY（Avanafil)-1
- CBNumber:
- CB6703107
- Molecular Formula:
- C13H17NO
- Molecular Weight:
- 203.28
- MDL Number:
- MFCD02258902
- MOL File:
- 22065-85-6.mol
- MSDS File:
- SDS
Last updated:2023-04-23 13:52:06
| Melting point | 145-149 °C |
|---|---|
| Boiling point | 315.4 °C/760 mmHg |
| Density | 1.026 g/mL at 25 °C |
| refractive index |
n |
| Flash point | >230 °F |
| storage temp. | Inert atmosphere,Store in freezer, under -20°C |
| solubility | Acetone (Slightly), Chloroform (Slightly), Dichloromethane (Slightly), DMSO (Sli |
| pka | 8.04±0.10(Predicted) |
| form | Liquid |
| color | Clear colorless to pale yellow |
| Sensitive | Air Sensitive |
| InChIKey | SGIBOXBBPQRZDM-UHFFFAOYSA-N |
| CAS DataBase Reference | 22065-85-6(CAS DataBase Reference) |
| FDA UNII | S5RKG3HX5A |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301-H318 | |||||||||
| Precautionary statements | P280-P301+P310+P330-P305+P351+P338+P310 | |||||||||
| Hazard Codes | T | |||||||||
| Risk Statements | 25-41 | |||||||||
| Safety Statements | 26-28-36/37/39 | |||||||||
| RIDADR | UN 2810 6.1/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| PackingGroup | Ⅲ | |||||||||
| HS Code | 29333990 | |||||||||
| NFPA 704 |
|
N-Benzylpiperidine-4-carboxaldehyde price More Price(33)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 664081 | N-Benzylpiperidine-4-carboxaldehyde 95% | 22065-85-6 | 1g | $67.4 | 2023-06-20 | Buy |
| Sigma-Aldrich | 664081 | N-Benzylpiperidine-4-carboxaldehyde 95% | 22065-85-6 | 5g | $271 | 2023-06-20 | Buy |
| TCI Chemical | B3190 | 1-Benzyl-4-piperidinecarboxaldehyde >96.0%(GC)(T) | 22065-85-6 | 5g | $65 | 2024-03-01 | Buy |
| TCI Chemical | B3190 | 1-Benzyl-4-piperidinecarboxaldehyde >96.0%(GC)(T) | 22065-85-6 | 25g | $209 | 2024-03-01 | Buy |
| TRC | B288620 | 1-Benzyl-4-piperidine-carboxaldehyde | 22065-85-6 | 25g | $540 | 2021-12-16 | Buy |
N-Benzylpiperidine-4-carboxaldehyde Chemical Properties,Uses,Production
Synthesis
A round
bottom flask was charged with oxalyl chloride (16.2 g, 0.12
mol), dichloromethane (150 mL) and anhydrous dimethyl sulfoxide
(20 mL). Stir the reaction mixture mass in a cryo bath at -70 °C
for 15 min. The resulting mixture is charged dropwise with N-benzyl piperidine alcohol 3 (20 g, 0.097 mol), along with
triethylamine (24.6 g, 0.24 mol) and continued stirring for the
next 15 min. After that, the mass is allowed to attain room
temperature overnight, then diluted with dichloromethane (100
mL) and quenched with cold water. The organic layer was
washed subsequently with 5 % HCl solution, brine solution, 5
% sodium bicarbonate solution and dried over sodium sulfate.
Toluene was removed in vacuo to afford N-Benzylpiperidine-4-carboxaldehyde (19.2 g, 96 %).
Chemical Properties
Colorless Oil
Uses
Reactant for:
- Stereospecific allylic alkylation
- Reactions of Grignard reagents with carbonyl compounds
- Fluorodenitrations and nitrodehalogenations for labeled PET ligands and fluoropharmaceuticals
- Selective α1 receptor antagonists
Reactant for synthesis of:
- Donepezil
- MCH-R1 antagonists
N-Benzylpiperidine-4-carboxaldehyde Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 366)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21634 | 55 |
| Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 +8617317452075 | jack.li@time-chemicals.com | China | 1803 | 55 |
| Hangzhou FandaChem Co.,Ltd. | +8615858145714 | FandaChem@Gmail.com | China | 9214 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29882 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| Xi'an Kono chem co., Ltd., | 029-86107037 13289246953 | info@konochemical.com | China | 2993 | 58 |
| Shandong chuangyingchemical Co., Ltd. | 18853181302 | sale@chuangyingchem.com | CHINA | 5906 | 58 |
| Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14332 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39894 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
View Lastest Price from N-Benzylpiperidine-4-carboxaldehyde manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2022-10-18 | N-Benzylpiperidine-4-carboxaldehyde
22065-85-6
|
US $0.00-0.00 / kg | 1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. | |
 |
2021-12-22 | N-Benzylpiperidine-4-carboxaldehyde
22065-85-6
|
US $2.00 / KG | 1KG | 98% | 500ton/Month | Qiuxian Baitai New Material Co., LTD | |
 |
2019-07-06 | N-Benzylpiperidine-4-carboxaldehyde
22065-85-6
|
US $2.00 / kg | 1kg | 99% | ask | Career Henan Chemical Co |
-
- N-Benzylpiperidine-4-carboxaldehyde
22065-85-6
- US $0.00-0.00 / kg
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- N-Benzylpiperidine-4-carboxaldehyde
22065-85-6
- US $2.00 / KG
- 98%
- Qiuxian Baitai New Material Co., LTD
-
- N-Benzylpiperidine-4-carboxaldehyde
22065-85-6
- US $2.00 / kg
- 99%
- Career Henan Chemical Co
22065-85-6(N-Benzylpiperidine-4-carboxaldehyde)Related Search:
Benzyl chloride
DROPERIDOL
N-Benzyl-4-piperidone
Benzyltrimethylammonium chloride
Benzyltriethylammonium chloride
Haloperidol
Ethyl 1-benzylpiperidine-4-carboxylate
Phenylacetone
Diphenoxylate
1-BENZYL-3-OXO-PIPERIDINE-4-CARBOXYLIC ACID ETHYL ESTER
1of4
1-BENZYL-4-PIPERIDINECARBALDEHYDE
1-BENZYL-4-PIPERIDINECARBOXALDEHYDE
N-Benzyl-4-Formyl Piperidine
1-Benzy-4-Piperidine Carboxyaldehyde
1-Benzyl-4-Formyl Piperidine
1-Benzy-4-Piperidine Carboxaldehyde
1-benzy-4-piperidine arboxyaldehyde
1-Benzyl-4-PiperidineCarboxyaldehyde
1-BENZYLPIPERIDINE-4-CARBALDEHYDE 96%
4-Formyl-1-benzylpiperidine
N-(Phenylmethyl)piperidine-4-carboxaldehyde
N-Benzyl-4-formylpiperidin
4-PIPERIDINECARBOXALDEHYDE,1-(PHENYLMETHYL)
N-Benzylpiperidine-4-carboxyaldehyde
N-Benzy-4-Piperidine Carboxaldehyde
1-Benzylisonipecotaldehyde
N-BENZYLPIPERIDINE-4-CARBOXALDEHYDE
1-BENZYL-PIPERIDINE-4-CARBALDEHYDE
N‐Benzylisonipecotinaldehyde
ZERO/005913
1-Benzyl-4-piperidinecarboxaldehyde >
N-Benzylpiperidine-4-carbaldehyde
-Benzylpiperidine-4-carboxaldehyde
1-benzyl -4-piperdine aldehyde
1-Benzylpiperidine-4-carboxaldehyde 95%
N-benzyl piperdine aldehyde
Donepezil Impurity 40
N-Benzyl-4-Piperidinecarboxaldehyde95%
1-(Phenylmethyl)-4-piperidinecarboxaldehyde
1-Benzylpiperidine-4-carboxaldehyde
1-(Phenylmethyl)-4-piperidinecarbaldehyde
1-Benzyl-4-piperidinecarboxaldehyde,1-Benzyl-4-formylpiperidine
1-Benzyl-4-formylpiperidine, [(4-Formylpiperidin-1-yl)methyl]benzene
N-Benzylpiperidine-4-carboxaldehyde 95%
Benzylpiperidine-4-carboxaldehyde
RSYY（Avanafil)-1
N-Benzylpiperdine carboxaldehyde
1-BENZYL 4 PIPERDINE CARBOXALDEHYDE
1-Benzylpiperidine-4-Carboxaldehyde (BPCA)
22065-85-6
2065-85-6
2447-57-7
Building Blocks
Piperidines
Heterocyclic Building Blocks
pharmacetical
Alcohol Aldehyde & acid series
Piperidine
(intermediate of donepezil)
Aromatics
Heterocycles
Building Blocks
Heterocyclic Building Blocks
Piperidines