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(R)-(+)-2-(4-Hydroxyphenoxy)propionic acid

(R)-(+)-2-(4-Hydroxyphenoxy)propionic acid Structure
(R)-(+)-2-(4-Hydroxyphenoxy)propionic acid structure
CAS No.
94050-90-5
Chemical Name:
(R)-(+)-2-(4-Hydroxyphenoxy)propionic acid
Synonyms
D-HPPA;(R)-2-(4-HYDROXYPHENOXY)PROPIONIC ACID;(R)-(+)-2-(4-Hydroxy;Hydroxy phenyl propionate;Phenyl Acetate Impurity 24;HYDROXYPHENOXYPROPIONIC ACID;(R)-(+)-2-(4-Hydroxyphenoxy);(-)-p-Hydroxyhydratropic acid;(R)-(+)-2-(4-Hydroxyphenoxy)Pr;R-(+)-2-(HYDROXYPHENOXY)PROPIONIC
CBNumber:
CB6711601
Molecular Formula:
C9H10O4
Molecular Weight:
182.17
MDL Number:
MFCD00274088
MOL File:
94050-90-5.mol
MSDS File:
SDS
Last updated:2024-07-29 15:17:36
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(R)-(+)-2-(4-Hydroxyphenoxy)propionic acid Properties

Melting point 145-148 °C (lit.)
alpha 58 º (c=1, MeOH)
Boiling point 367.5±17.0 °C(Predicted)
Density 1.302±0.06 g/cm3(Predicted)
refractive index 38 ° (C=0.1, MeOH)
storage temp. Inert atmosphere,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
pka 3.32±0.10(Predicted)
color Off-White
optical activity [α]20/D +58°, c = 1 in methanol
InChI InChI=1S/C9H10O4/c1-6(9(11)12)13-8-4-2-7(10)3-5-8/h2-6,10H,1H3,(H,11,12)/t6-/m1/s1
InChIKey AQIHDXGKQHFBNW-ZCFIWIBFSA-N
SMILES C(O)(=O)[C@H](OC1=CC=C(O)C=C1)C
CAS DataBase Reference 94050-90-5(CAS DataBase Reference)
FDA UNII WSI8A5QG10

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS05
Signal word  Danger
Hazard statements  H318
Precautionary statements  P280-P305+P351+P338
Hazard Codes  Xi
Risk Statements  41
Safety Statements  26-39
WGK Germany  1
HS Code  29189900

(R)-(+)-2-(4-Hydroxyphenoxy)propionic acid price More Price(21)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 474533 (R)-(+)-2-(4-Hydroxyphenoxy)propionic acid 98% 94050-90-5 25g $40.8 2024-03-01 Buy
TCI Chemical H0937 (R)-(+)-2-(4-Hydroxyphenoxy)propionic Acid >98.0%(GC)(T) 94050-90-5 5g $24 2022-04-27 Buy
TRC H949715 (R)-(+)-2-(4-Hydroxyphenoxy)propionic acid 94050-90-5 10g $55 2021-12-16 Buy
Chem-Impex 39505 (R)-(+)-2-(4-Hydroxyphenoxy)propionicacid,≥98%(Assaybytitration,GC) ≥98%(Assaybytitration,GC) 94050-90-5 5G $25.63 2021-12-16 Buy
Frontier Specialty Chemicals JK312017 (R)-(+)-2-(4-Hydroxyphenoxy)propionic acid 98% 94050-90-5 5g $28 2021-12-16 Buy
Product number Packaging Price Buy
474533 25g $40.8 Buy
H0937 5g $24 Buy
H949715 10g $55 Buy
39505 5G $25.63 Buy
JK312017 5g $28 Buy

(R)-(+)-2-(4-Hydroxyphenoxy)propionic acid Chemical Properties,Uses,Production

Chemical Properties

White to off-white powder or crystal

Uses

(R)-(+)-2-(4-Hydroxyphenoxy)propionic Acid is a degradation product of Cyhalofop-butyl (C989385); an aryloxyphenoxypropionate compound that is used as a herbicide to eliminate grass weeds in rice fields. Cyhalofop-butyl works by selectively inhibiting acetyl CoA carboxylase, an enzyme that is important for the metabolism of fatty acids.

Synthesis

(R)-2-(4-hydroxyphenoxy)propionic acid ((R)-HPOPA) is an essential intermediate for the production of chiral aryloxyphenoxypropionic acid-type herbicides such as clod inafop-propargyl, cyhalofop-butyl, fenoxaprop-p-ethyl, metam ifop, quizalofop-p-ethyl, and quizalofop-p-tefuryl. In general, there are three chemical methods for the preparation of (R)-HPOPA: (1) resolution of racemic HPOPA with alkaloids such as quinine, cinchonine, ephedrine, vauquline or chiral agents such as S-(?)-α-phenylethylamine, L-(+)-chloromethane, R-(+)-α-isopropyl-4-chlorobenzylamine and (2) asymmetric synthesis from L-lactic acids or L-alanine. However, these methods are not always useful for industrial applications because of expensive reagents, problems with enantiopurity of product and low yields. Regioselective hydroxylation of (R)-2-phenoxypropionic acid ((R)-POPA) by microbes is a highly feasible method for the production of (R)-HPOPA, which under mild conditions allows complete transformation of substrate into a single stereoisomeric product with a high yield and without byproduct formation[1-2].

References

[1] Hai-Feng Hu . “A rapid throughput assay for screening (R)-2-(4-hydroxyphenoxy)propionic acid producing microbes.” Journal of microbiological methods 158 (2019): Pages 44-51.
[2] Haiyan Zhou. “An efficient route towards R-2-phenoxypropionic acid synthesis for biotransformative production of R-2-(4-hydroxyphenoxy)propionic acid.” Chinese Journal of Chemical Engineering 32 (2021): Pages 315-323.

(R)-(+)-2-(4-Hydroxyphenoxy)propionic acid synthesis

96562-58-2
94050-90-5
Synthesis of (R)-(+)-2-(4-Hydroxyphenoxy)propionic acid from Methyl (R)-(+)-2-(4-hydroxyphenoxy)propanoate

(R)-(+)-2-(4-Hydroxyphenoxy)propionic acid Preparation Products And Raw materials

Raw materials

Preparation Products

Quizalofop-P

(R)-(+)-2-(4-Hydroxyphenoxy)propionic acid Suppliers

Global( 376)Suppliers
Supplier Tel Email Country ProdList Advantage
shandong exelon biochem co.ld
+86-533-2119995 +8615053330977 451614802@QQ.com China 30 58
Hebei Mojin Biotechnology Co., Ltd 		+8613288715578 sales@hbmojin.com China 12458 58
Hebei Guanlang Biotechnology Co,.LTD 		+86-19930503253; +8619930503252 daisy@crovellbio.com China 5835 58
Nantong Guangyuan Chemicl Co,Ltd 		+undefined17712220823 admin@guyunchem.com China 616 58
hebei hongtan Biotechnology Co., Ltd 		+86-86-1913198-3935 +8617331935328 sales03@chemcn.cn China 973 58
Capot Chemical Co.,Ltd. 		571-85586718 +8613336195806 sales@capotchem.com China 29798 60
Shanghai Daken Advanced Materials Co.,Ltd 		+86-371-66670886 info@dakenam.com China 16209 58
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21669 55
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29898 58
NINGBO INNO PHARMCHEM CO., LTD. 		13867897135 sales@nbinno.com CHINA 925 58
Supplier Advantage
shandong exelon biochem co.ld
58
Hebei Mojin Biotechnology Co., Ltd 		58
Hebei Guanlang Biotechnology Co,.LTD 		58
Nantong Guangyuan Chemicl Co,Ltd 		58
hebei hongtan Biotechnology Co., Ltd 		58
Capot Chemical Co.,Ltd. 		60
Shanghai Daken Advanced Materials Co.,Ltd 		58
Henan Tianfu Chemical Co.,Ltd. 		55
career henan chemical co 		58
NINGBO INNO PHARMCHEM CO., LTD. 		58

View Lastest Price from (R)-(+)-2-(4-Hydroxyphenoxy)propionic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(R)-(+)-2-(4-Hydroxyphenoxy)propionic acid pictures 2024-08-05 (R)-(+)-2-(4-Hydroxyphenoxy)propionic acid
94050-90-5
 US $0.00 / KG 1KG 99% 1000mt/year Jinan Finer Chemical Co., Ltd
(R)-(+)-2-(4-Hydroxyphenoxy)propionic acid pictures 2024-07-29 (R)-(+)-2-(4-Hydroxyphenoxy)propionic acid
94050-90-5
 US $5.00-2.00 / KG 1KG 99% 10000kg Hebei Guanlang Biotechnology Co,.LTD
(R)-(+)-2-(4-Hydroxyphenoxy)propionic acid pictures 2024-06-26 (R)-(+)-2-(4-Hydroxyphenoxy)propionic acid
94050-90-5
 US $30.00 / kg 1kg 98% 2000kg hebei hongtan Biotechnology Co., Ltd

(R)-(+)-2-(4-Hydroxyphenoxy)propionic acid Spectrum

(R)-(+)-2-(4-Hydroxyphenoxy)propionic acid(94050-90-5)MS(R)-(+)-2-(4-Hydroxyphenoxy)propionic acid(94050-90-5)1HNMR(R)-(+)-2-(4-Hydroxyphenoxy)propionic acid(94050-90-5)13CNMR(R)-(+)-2-(4-Hydroxyphenoxy)propionic acid(94050-90-5)IR1(R)-(+)-2-(4-Hydroxyphenoxy)propionic acid(94050-90-5)IR2

94050-90-5((R)-(+)-2-(4-Hydroxyphenoxy)propionic acid)Related Search:

4-Hydroxybenzoic acid 4-Hydroxybenzaldehyde Propionic anhydride L(+)-Lactic acid Propionic acid
3-(4-Hydroxyphenyl)propionic acid Anisole Methylparaben 3-(4-Methoxyphenyl)propionic acid (Trifluoromethoxy)benzene
Nandrolone phenylpropionate Methyl (R)-(+)-2-(4-hydroxyphenoxy)propanoate Butyl (R)-(+)-2-(4-hydroxyphenoxy)propionate Ethyl (R)-(+)-2-(4-hydroxyphenoxy)propionate Propynyl (R)-(+)-2-(4-hydroxyphenoxy)propionate
2-(4-HYDROXYPHENYL)PROPIONIC ACID 2-(4-HYDROXYPHENOXY)PROPIONIC ACID HYDRAZIDE 2-(p-Hydroxyphenoxy)propionic acid,2-(4-HYDROXYPHENOXY)PROPIONIC ACID

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（R）-（+）-（4-hydroxyphenoxy)-propionic acid (2R)-2-(4-hydroxyphenoxy)propanoic acid R-(+)-2-(HYDROXYPHENOXY)PROPIONIC (R)-(+)-2-(HYDROXYPHENOXY)PROPIONIC ACID (R)-2-(4-HYDROPHENOXY)PROPIONIC ACID R-2-(4-HYDROXYPHENOXY)PROPANOIC ACID (R)-(+)-2-(4-HYDROXYPHENOXY)PROPIONIC ACID D-2-(4-HYDROXYPHENOXY)PROPIONIC ACID (R)-(+)-2-(4-HYDROXYPENOXY)PROPIONIC ACID HYDROXYPHENOXYPROPIONIC ACID (R)-(+)-2-(4-Hydroxyphenoxy)Pr R-(+)-2-(4-HYDROXYPHENYL)PROPIONIC ACID R-2-(4-Hydroxyphenoxy)propanoic aicd R-(+)-2-(4-Hydrobenzoxy)propionic acid (-)-p-Hydroxyhydratropic acid [R,(-)]-2-(p-Hydroxyphenyl)propionic acid (S)-2-(4-Hydroxyphenyl)propionic acid [S,(+)]-2-(p-Hydroxyphenyl)propionic acid (R)-2-(p-Hydroxyphenoxy)propionic acid (R)-(+)-2-(4-Hydroxy Propanoicacid, 2-(4-hydroxyphenoxy)-, (2R)- R - (+) - 2 - (4 - hydroxyl phenoxy) propionic acid (R)-(+)-2-(4-Hydroxyphenoxy)propionic acid 98% Hydroxy phenyl propionate (R) -(+) -2- (4-Hydroxyphenoxy) propanoic acid (D-HPPA) (R)-(+)-2-(4-Hydroxyphenoxy)propionicAcid> (R)-(+)-2-(4-Hydroxyphenoxy)propionic acid ISO 9001：2015 REACH (R)-(+)-2-(4-Hydroxyphenoxy) Pesticide Intermediate CAS?94050-90-5?(R) - (+) -2- (4-Hydroxy Phenoxy) Propionic Acid (R)-2-(4-HYDROXYPHENOXY)PROPIONIC ACID D-HPPA (R-(+-2-(4-hydroxyphenoxy)propylene Sour Phenyl Acetate Impurity 24 94050-90-5 Carboxylic Acids Asymmetric Synthesis Chiral Building Blocks Organic Building Blocks Carboxylic Acids Chiral Building Blocks Organic Building Blocks CHIRAL COMPOUNDS Aromatic Propionic Acids