Flopropione
- CAS No.
- 2295-58-1
- Chemical Name:
- Flopropione
- Synonyms
- Labroda;Chlonarin;Pasmus;SKL632;Argobyl;Ecapron;Flopion;Cospanon;Labrodax;Profenon
- CBNumber:
- CB6780852
- Molecular Formula:
- C9H10O4
- Molecular Weight:
- 182.17
- MDL Number:
- MFCD00016456
- MOL File:
- 2295-58-1.mol
| Melting point | 177°C |
|---|---|
| Boiling point | 275.56°C (rough estimate) |
| Density | 1.2481 (rough estimate) |
| refractive index | 1.4500 (estimate) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | Soluble in DMSO |
| form | powder to crystal |
| pka | 7.49±0.45(Predicted) |
| color | White to Orange to Green |
| Merck | 14,4106 |
| LogP | 2.600 (est) |
| CAS DataBase Reference | 2295-58-1(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | 05V5NVB5Y1 |
| NIST Chemistry Reference | Flopropione(2295-58-1) |
| EPA Substance Registry System | 1-Propanone, 1-(2,4,6-trihydroxyphenyl)- (2295-58-1) |
| UNSPSC Code | 12352200 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319 |
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36/37/39 |
| RTECS | UH4429100 |
| HS Code | 2914.50.3000 |
Flopropione price More Price(11)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | T0887 | 2',4',6'-Trihydroxypropiophenone >98.0%(GC)(T) | 2295-58-1 | 25g | $117 | 2024-03-01 | Buy |
| AK Scientific | J55538 | Flopropione | 2295-58-1 | 25g | $172 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0007822 | 2',4',6'-TRIHYDROXYPROPIOPHENONE 95.00% | 2295-58-1 | 5MG | $504.83 | 2021-12-16 | Buy |
| ChemScene | CS-8184 | Flopropione 98.93% | 2295-58-1 | 100mg | $84 | 2021-12-16 | Buy |
| Crysdot | CD31002584 | Flopropione 95+% | 2295-58-1 | 100mg | $101 | 2021-12-16 | Buy |
Flopropione Chemical Properties,Uses,Production
Uses
antispasmodic
Definition
ChEBI: Flopropione is an organic molecular entity.
Preparation
Preparation by reaction of propionitrile with phlo-roglucinol (Hoesch reaction);
Preparation by reaction of propionic anhydride with phloroglucinol
in the presence of concentrated sulfuric acid (one drop) at 130° for 5 min ? (65%)
in the presence of Amberlite IR-120 (cation exchange resin sulfonic acid ? type) at 160° for 2–3 h (42%). N.B.: Zeokarb 225 was found to be as effective
in the presence of boron trifluoride etherate at 10° (62–65%)
Preparation by reaction of propionyl chloride with phloroglucinol
in the presence of aluminium chloride in nitrobenzene/carbon disulfide ? solution (76%), in nitrobenzene at 60° (55%) or without solvent at 50° (70%)
in the presence of boron trifluoride etherate at 10° (compound ? 3) (62–65%).
in vivo
The effect of Flopropione as an antispasmodic agent on the rate of passing a calculus from the urinary tract has been compared retrospectively with patients in whom passage was spontaneous. Flopropine has been shown, with statistical significance, to be superior to the control in cumulative passage rate after initiation of administration. Flopropine has been shown to exert a spasmolytic effect not only on smooth muscle of the gastrointestinal tract but also on smooth muscle of the pancreatobiliary and urinary systems[3].
IC 50
5-HT1A Receptor; COMT
Flopropione Preparation Products And Raw materials
Raw materials
Preparation Products
Flopropione Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29808 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32248 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| AFINE CHEMICALS LIMITED | +86-0571-85134551 | sales@afinechem.com | China | 15415 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6391 | 58 |
| Shaanxi Didu New Materials Co. Ltd | +86-89586680 +86-13289823923 | 1026@dideu.com | China | 8808 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38652 | 58 | |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +86-18621343501; +undefined18621343501 | product@acmec-e.com | China | 33338 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| TargetMol Chemicals Inc. | +8613564774135 | zijue.cai@tsbiochem.com | United States | 19898 | 58 |
View Lastest Price from Flopropione manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-04-30 | Flopropione
2295-58-1
|
US $30.00-56.00 / mg | 100% | 10g | TargetMol Chemicals Inc. | ||
 |
2024-11-19 | Flopropione
2295-58-1
|
US $30.00-56.00 / mg | 100% | 10g | TargetMol Chemicals Inc. | ||
 |
2020-01-10 | Flopropione
2295-58-1
|
US $1.00 / KG | 1KG | ≥98% | 20 tons | Career Henan Chemical Co |
-
- Flopropione
2295-58-1
- US $30.00-56.00 / mg
- 100%
- TargetMol Chemicals Inc.
-
- Flopropione
2295-58-1
- US $30.00-56.00 / mg
- 100%
- TargetMol Chemicals Inc.
-
- Flopropione
2295-58-1
- US $1.00 / KG
- ≥98%
- Career Henan Chemical Co