ChemicalBook >> CAS DataBase List >>SIAIS178
SIAIS178
- CAS No.
- 2376047-73-1
- Chemical Name:
- SIAIS178
- Synonyms
- SIAIS178
- CBNumber:
- CB68049335
- Molecular Formula:
- C50H62ClN11O6S2
- Molecular Weight:
- 1012.68
- MDL Number:
- MFCD32689531
- MOL File:
- Mol file
Last updated:2024-07-02 08:55:14
SIAIS178 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0103903 | SIAIS178 99.48% | 2376047-73-1 | 1mg | $200 | 2021-12-16 | Buy |
| ChemScene | CS-0103903 | SIAIS178 99.48% | 2376047-73-1 | 5mg | $480 | 2021-12-16 | Buy |
| ChemScene | CS-0103903 | SIAIS178 99.48% | 2376047-73-1 | 10mg | $650 | 2021-12-16 | Buy |
| ChemScene | CS-0103903 | SIAIS178 99.48% | 2376047-73-1 | 50mg | $1950 | 2021-12-16 | Buy |
| ChemScene | CS-0103903 | SIAIS178 99.48% | 2376047-73-1 | 100mg | $2750 | 2021-12-16 | Buy |
SIAIS178 Chemical Properties,Uses,Production
Description
SIAIS178 is a potent BCR-ABL Degrader. SIAIS178 induces proper interaction between BCR-ABL and VHL ligase leading to effective degradation of BCR-ABL protein, achieves significant growth inhibition of BCR-ABL+ leukemic cells in vitro, and induces substantial tumor regression against K562 xenograft tumors in vivo. In addition, SIAIS178 also degrades several clinically relevant resistance-conferring mutations. Our data indicate that SIAIS178 as efficacious BCR-ABL degrader warrants extensive further investigation for the treatment of BCR-ABL+ leukemia.
SIAIS178 Preparation Products And Raw materials
Raw materials
Preparation Products
SIAIS178 Suppliers
Global( 10)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Shanghai Chaolan Chemical Technology Center | QQ:65489617 15618227136 | info@SuperLan-chem.com | China | 9887 | 58 |
| Jilin Province Woda Biotechnology Co., Ltd. | 13504435624 | 1927928688@qq.com | China | 1381 | 58 |
| Chengdu Peter-like Biotechnology Co., Ltd. | 028-81700200 18108052721 | 2850505130@qq.com | China | 5182 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
| Changzhou Bojia Biomedical Technology Co., Ltd. | 2122619822 | czbjpharma@126.com | China | 18488 | 58 |
| Shanghai Easy CDMO Co.,Ltd | 021-61734564 | August@easycdmo.com | China | 10010 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | 18143011203 | ET-market@chemextension.com | China | 41846 | 58 |
| RD International Technology Co., Limited | 18024082417 | market@ubiochem.com | China | 9282 | 58 |
SIAIS178
2376047-73-1