Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>1-Piperazinecarboxylic acid, 4-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]-, 1,1-dimethylethyl ester

1-Piperazinecarboxylic acid, 4-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]-, 1,1-dimethylethyl ester

1-Piperazinecarboxylic acid, 4-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]-, 1,1-dimethylethyl ester Structure
1-Piperazinecarboxylic acid, 4-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]-, 1,1-dimethylethyl ester structure
CAS No.
2222114-64-7
Chemical Name:
1-Piperazinecarboxylic acid, 4-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]-, 1,1-dimethylethyl ester
Synonyms
Thalidomide-piperazine-Boc;Thalidomide-5-piperazine-Boc;tert-butyl 4-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)piperazine-1-carboxylate;1-Piperazinecarboxylic acid, 4-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]-, 1,1-dimethylethyl ester
CBNumber:
CB68192310
Molecular Formula:
C22H26N4O6
Molecular Weight:
442.46
MDL Number:
MFCD32705088
MOL File:
2222114-64-7.mol
Last updated:2024-10-23 13:36:13
Request For Quotation

1-Piperazinecarboxylic acid, 4-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]-, 1,1-dimethylethyl ester Properties

Boiling point 674.6±55.0 °C(Predicted)
Density 1.373±0.06 g/cm3(Predicted)
solubility DMSO : 41.67 mg/mL (94.18 mM; Need ultrasonic)
pka 10.83±0.40(Predicted)
form Solid
color Light yellow to yellow

1-Piperazinecarboxylic acid, 4-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]-, 1,1-dimethylethyl ester Chemical Properties,Uses,Production

Biological Activity

Thalidomide-piperazine-Boc is an intermediate that can be used in the synthesis of B-cell lymphoma 6 protein (BCL6) PROTAC[1].

References

[1]. Michael Berlin, et al. Bifunctional molecules containing an e3 ubiquitine ligase binding moiety linked to a bcl6 targeting moiety. WO2021077010A1.

1-Piperazinecarboxylic acid, 4-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]-, 1,1-dimethylethyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

1-Piperazinecarboxylic acid, 4-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]-, 1,1-dimethylethyl ester Suppliers

Global( 38)Suppliers
Supplier Tel Email Country ProdList Advantage
Zhejiang J&C Biological Technology Co.,Limited 		+1-2135480471 +1-2135480471 sales@sarms4muscle.com China 10473 58
Alfa Chemistry 		Info@alfa-chemistry.com United States 24072 58
TargetMol Chemicals Inc. 		support@targetmol.com United States 38631 58
Hebei Miaoyin Technology Co.,Ltd 		+86-17367732028 +86-17367732028 kathy@hbyinsheng.com China 3512 58
Shanxi Tihondan Pharmaceutical Technology Co., Ltd 		+8618235132063 sales@tihondan.com China 3741 58
Wuhan Jingkang en Biomedical Technology Co., Ltd 		+8613720134139 orders@jknbiochem.com China 5221 58
taizhoushuocheng Pharmaceutical Technology Co., Ltd 19331071838 19331071838 wang666xt@126.com China 186 58
Daicel Chiral Technologies (China)CO.,LTD 021-50460086-9 15921403865 han_yajun@dctc.daicel.com China 7195 65
ShangHai Angti Biotechnology Co., Ltd. 13764913901 info@angtibio.com China 5007 55
Shanghai Changyan Chem & Tech Co., Ltd. 021-20242659 18930833303 Sales@changyanchem.cn China 5010 55
Supplier Advantage
Zhejiang J&C Biological Technology Co.,Limited 		58
Alfa Chemistry 		58
TargetMol Chemicals Inc. 		58
Hebei Miaoyin Technology Co.,Ltd 		58
Shanxi Tihondan Pharmaceutical Technology Co., Ltd 		58
Wuhan Jingkang en Biomedical Technology Co., Ltd 		58
taizhoushuocheng Pharmaceutical Technology Co., Ltd 58
Daicel Chiral Technologies (China)CO.,LTD 65
ShangHai Angti Biotechnology Co., Ltd. 55
Shanghai Changyan Chem & Tech Co., Ltd. 55

View Lastest Price from 1-Piperazinecarboxylic acid, 4-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]-, 1,1-dimethylethyl ester manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Thalidomide-piperazine-Boc pictures 2024-10-24 Thalidomide-piperazine-Boc
2222114-64-7
 US $46.00-78.00 / mg 10g TargetMol Chemicals Inc.

2222114-64-7(1-Piperazinecarboxylic acid, 4-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]-, 1,1-dimethylethyl ester)Related Search:

1-Piperidinecarboxylic acid, 3-(4-hydroxyphenyl)-2,6-dioxo-, 1,1-dimethylethyl ester Tert-butyl 4-(4-aMino-3-Methoxyphenyl)piperazine-1-carboxylate tert-butyl (S)-3-(cyanomethyl)piperazine-1-carboxylate 1-Piperidinecarboxylic acid, 3-(4-amino-1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-2,6-dioxo-, 1,1-dimethylethyl ester tert-Butyl 2,6-dioxo-3-(4-(prop-2-yn-1-yloxy)phenyl)piperidine-1-carboxylate
1-Piperazinecarboxylic acid, 4-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]-, 1,1-dimethylethyl ester tert-butyl 4-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)piperazine-1-carboxylate Thalidomide-piperazine-Boc Thalidomide-5-piperazine-Boc 2222114-64-7 chem-chemical