ChemicalBook >> CAS DataBase List >>(2alpha,6alpha,11R*)-1,2,3,4,5,6-hexahydro-6,11-dimethyl-2,6-methano-3-benzazocin-8-ol

(2alpha,6alpha,11R*)-1,2,3,4,5,6-hexahydro-6,11-dimethyl-2,6-methano-3-benzazocin-8-ol

(2alpha,6alpha,11R*)-1,2,3,4,5,6-hexahydro-6,11-dimethyl-2,6-methano-3-benzazocin-8-ol structure

CAS No.: 25144-78-9

Chemical Name:: (2alpha,6alpha,11R*)-1,2,3,4,5,6-hexahydro-6,11-dimethyl-2,6-methano-3-benzazocin-8-ol

Synonyms: dl-Normetazocine;Einecs 246-653-7;Pentazocine Related Compound A;alpha-5,9-Dimethyl-2'-hydroxy-6,7-benzomorphan hydrochloride;8-Hydroxy-2,6-methano-6α,11α-dimethyl-1,2,3,4,5,6-hexahydro-3-benzazocin;2,6-Methano-3-benzazocin-8-ol, 1,2,3,4,5,6-hexahydro-6,11-dimethyl-, trans- (8ci);2,6-Methano-3-benzazocin-8-ol, 1,2,3,4,5,6-hexahydro-6,11-dimethyl-, (2R,6R,11R)-rel-;(2alpha,6alpha,11R*)-1,2,3,4,5,6-hexahydro-6,11-dimethyl-2,6-methano-3-benzazocin-8-ol;2,6-Methano-3-benzazocin-8-ol, 1,2,3,4,5,6-hexahydro-6,11-alpha-dimethyl-, hydrochloride;2,6-Methano-3-benzazocin-8-ol, 6,11-alpha-dimethyl-1,2,3,4,5,6-hexahydro-, hydrochloride

CBNumber:: CB6912035

Molecular Formula:: C14H19NO

Molecular Weight:: 217.31

MDL Number:

MOL File:: 25144-78-9.mol

Last updated:2023-05-15 10:43:58

(2alpha,6alpha,11R*)-1,2,3,4,5,6-hexahydro-6,11-dimethyl-2,6-methano-3-benzazocin-8-ol Properties

Boiling point	355.8±42.0 °C(Predicted)
Density	1.088±0.06 g/cm3(Predicted)
solubility	Acetone (Slightly), Methanol (Slightly)
pka	9.79±0.60(Predicted)
form	Solid
color	Pale Beige to Light Brown
EWG's Food Scores	1

SAFETY

Risk and Safety Statements

Toxicity	LD50 scu-mus: 84 mg/kg 31ZPAG 2,135,1966

(2alpha,6alpha,11R*)-1,2,3,4,5,6-hexahydro-6,11-dimethyl-2,6-methano-3-benzazocin-8-ol Chemical Properties,Uses,Production

Chemical Properties

Tan to Light Brown Solid

Uses

Antagonistic and analgetic activities. Precursor for the preparation of (+/-)-Pentazocine, (+/-)-Cyclazocine

Hazard

A poison.

Safety Profile

A poison by subcutaneous route.When heated to decomposition it emits toxic vapors ofNOx and HCl.

(2alpha,6alpha,11R*)-1,2,3,4,5,6-hexahydro-6,11-dimethyl-2,6-methano-3-benzazocin-8-ol Preparation Products And Raw materials

Raw materials

Preparation Products

2,6-Methano-3-benzazocin-8-ol, 1,2,3,4,5,6-hexahydro-6,11-alpha-dimethyl-, hydrochloride 2,6-Methano-3-benzazocin-8-ol, 1,2,3,4,5,6-hexahydro-6,11-dimethyl-, (2-alpha,6-alpha,11R*)- 2,6-Methano-3-benzazocin-8-ol, 1,2,3,4,5,6-hexahydro-6,11-dimethyl-, trans- (8ci) 2,6-Methano-3-benzazocin-8-ol, 6,11-alpha-dimethyl-1,2,3,4,5,6-hexahydro-, hydrochloride alpha-5,9-Dimethyl-2'-hydroxy-6,7-benzomorphan hydrochloride Einecs 246-653-7 dl-Normetazocine (2alpha,6alpha,11R*)-1,2,3,4,5,6-hexahydro-6,11-dimethyl-2,6-methano-3-benzazocin-8-ol 8-Hydroxy-2,6-methano-6α,11α-dimethyl-1,2,3,4,5,6-hexahydro-3-benzazocin 2,6-Methano-3-benzazocin-8-ol, 1,2,3,4,5,6-hexahydro-6,11-dimethyl-, (2R,6R,11R)-rel- Pentazocine Related Compound A 25144-78-9 Heterocycles Intermediates & Fine Chemicals Pharmaceuticals Chiral Reagents