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ChemicalBook >> CAS DataBase List >>n-(4-Chloro-3-cyano-7-ethoxy-6-quinolinyl) acetamide

n-(4-Chloro-3-cyano-7-ethoxy-6-quinolinyl) acetamide

n-(4-Chloro-3-cyano-7-ethoxy-6-quinolinyl) acetamide Structure
n-(4-Chloro-3-cyano-7-ethoxy-6-quinolinyl) acetamide structure
CAS No.
848133-76-6
Chemical Name:
n-(4-Chloro-3-cyano-7-ethoxy-6-quinolinyl) acetamide
Synonyms
Neratinib Impurity 40;Neratinib Intermediate 2;N-(4-Chloro-3-cyano-7-ethoxy-6-quinolinyl);4-chloro-3-cyano-7-ethoxy-6-N-acetylquinoline;N-(4-CHLORO-3-CYANO-7-ETHOXY-6-QUINOLINYL) ACETAMI;4-Chloro-3-cyano-7-ethoxy-6-(acetylamino)quinoline;N-(4-chloro-3-cyano-7-ethoxyquinolin-6-yl)acetaMide;4-Chloro-3-cyano-7-ethoxy-6-(N-acetylamino)quinoline;N-(4-CHLORO-3-CYANO-7-ETHOXYQUINOLINE-6-YL)ACETAMIDE;n-(4-Chloro-3-cyano-7-ethoxy-6-quinolinyl) acetamide
CBNumber:
CB6947307
Molecular Formula:
C14H12ClN3O2
Molecular Weight:
289.72
MDL Number:
MFCD09263704
MOL File:
848133-76-6.mol
MSDS File:
SDS
Last updated:2024-01-03 17:25:31
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n-(4-Chloro-3-cyano-7-ethoxy-6-quinolinyl) acetamide Properties

Melting point 250°C(lit.)
Boiling point 518.6±45.0 °C(Predicted)
Density 1.35±0.1 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility DMSO (Slightly, Heated)
form Solid
pka 13.13±0.43(Predicted)
color Light Yellow
FDA UNII U9EM282PCG

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302+H312+H332-H315-H319
Precautionary statements  P501-P261-P270-P271-P264-P280-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330-P302+P352+P312-P304+P340+P312
Hazard Codes  Xn
Risk Statements  22
HS Code  2933.49.7000
NFPA 704
0
2 0

n-(4-Chloro-3-cyano-7-ethoxy-6-quinolinyl) acetamide price More Price(35)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich CVT00119 N-(4-chloro-3-cyano-7-ethoxyquinolin-6-yl)acetamide 848133-76-6 1g $964 2024-03-01 Buy
TCI Chemical C3315 N-(4-Chloro-3-cyano-7-ethoxy-6-quinolinyl)acetamide >98.0%(HPLC)(N) 848133-76-6 1g $69 2024-03-01 Buy
TCI Chemical C3315 N-(4-Chloro-3-cyano-7-ethoxy-6-quinolinyl)acetamide >98.0%(HPLC)(N) 848133-76-6 5g $206 2024-03-01 Buy
TRC C365013 N-(4-Chloro-3-cyano-7-ethoxy-6-quinolinyl)acetamide 848133-76-6 1g $70 2021-12-16 Buy
Biosynth Carbosynth FC146854 N-(4-Chloro-3-cyano-7-ethoxy-6-quinolinyl)acetamide 848133-76-6 500mg $75 2021-12-16 Buy
Product number Packaging Price Buy
CVT00119 1g $964 Buy
C3315 1g $69 Buy
C3315 5g $206 Buy
C365013 1g $70 Buy
FC146854 500mg $75 Buy

n-(4-Chloro-3-cyano-7-ethoxy-6-quinolinyl) acetamide Chemical Properties,Uses,Production

Chemical Properties

yellow powder

Uses

N-(4-Chloro-3-cyano-7-ethoxy-6-quinolinyl)acetamide is used in synthesis of an antitumor agent, neratinib (N390090).

n-(4-Chloro-3-cyano-7-ethoxy-6-quinolinyl) acetamide synthesis

848133-75-5
848133-76-6
Synthesis of n-(4-Chloro-3-cyano-7-ethoxy-6-quinolinyl) acetamide from Acetamide, N-(3-cyano-7-ethoxy-4-hydroxy-6-quinolinyl)-

n-(4-Chloro-3-cyano-7-ethoxy-6-quinolinyl) acetamide Preparation Products And Raw materials

Raw materials

Methyl 5-acetaMido-4-ethoxy-2-nitrobenzoate Methyl 5-acetaMido-2-aMino-4-ethoxybenzoate N-(4-AMINO-2-ETHOXYPHENYL)ACETAMIDE ACETAMIDE, N-(2-HYDROXY-4-NITROPHENYL)- 4-ACETAMIDO-3-ETHOXYNITROBENZENE
Acetamide, N-(3-cyano-7-ethoxy-4-hydroxy-6-quinolinyl)- Benzoic acid, 3-(acetylamino)-4-ethoxy-, methyl ester 2-PROPENOIC ACID, 3-[[4-(ACETYLAMINO)-3-ETHOXYPHENYL]AMINO]-2-CYANO-, ETHYL ESTER Acetic anhydride 2-Amino-5-nitrophenol

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Preparation Products

n-(4-Chloro-3-cyano-7-ethoxy-6-quinolinyl) acetamide Suppliers

Global( 217)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd. 		+86-（0）57185586718 +86-13336195806 sales@capot.com China 29793 60
Shanghai Daken Advanced Materials Co.,Ltd 		+86-371-66670886 info@dakenam.com China 18940 58
Beijing Cooperate Pharmaceutical Co.,Ltd 		010-60279497 sales01@cooperate-pharm.com CHINA 1803 55
Shanghai Yingrui Biopharma Co., Ltd. 		+86-21-33585366 - 03@ sales03@shyrchem.com CHINA 738 60
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32965 60
Anqing Chico Pharmaceutical Co., Ltd. 		15380796838 chloewu@chicopharm.cn CHINA 340 58
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29879 58
Zhejiang ZETian Fine Chemicals Co. LTD 		+8618957127338 stella@zetchem.com China 2136 58
Hangzhou Cyanochem Co., Ltd. 		+86 17788583750 sales@cyanochem.com CHINA 281 58
Accela ChemBio Inc. 		+1-858-6993322 info@accelachem.com United States 18419 58
Supplier Advantage
Capot Chemical Co.,Ltd. 		60
Shanghai Daken Advanced Materials Co.,Ltd 		58
Beijing Cooperate Pharmaceutical Co.,Ltd 		55
Shanghai Yingrui Biopharma Co., Ltd. 		60
ATK CHEMICAL COMPANY LIMITED 		60
Anqing Chico Pharmaceutical Co., Ltd. 		58
career henan chemical co 		58
Zhejiang ZETian Fine Chemicals Co. LTD 		58
Hangzhou Cyanochem Co., Ltd. 		58
Accela ChemBio Inc. 		58

View Lastest Price from n-(4-Chloro-3-cyano-7-ethoxy-6-quinolinyl) acetamide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
N-(4-chloro-3-cyano-7-ethoxy-6-quinolinyl)acetamide pictures 2024-11-26 N-(4-chloro-3-cyano-7-ethoxy-6-quinolinyl)acetamide
848133-76-6
 US $0.00-0.00 / kg 1kg 98% 1 ton Nanjing Fred Technology Co., Ltd
N-(4-Chloro-3-cyano-7-ethoxy-6-quinolinyl)acetamide pictures 2023-08-16 N-(4-Chloro-3-cyano-7-ethoxy-6-quinolinyl)acetamide
848133-76-6
 US $80.00 / KG 1KG >99% 20tons Weijer International Trade (Hebei) Co., Ltd
N-(4-Chloro-3-cyano-7-ethoxy-6-quinolinyl)acetamide pictures 2023-08-16 N-(4-Chloro-3-cyano-7-ethoxy-6-quinolinyl)acetamide
848133-76-6
 US $80.00 / KG 1KG >99% 20tons Weijer International Trade (Hebei) Co., Ltd

n-(4-Chloro-3-cyano-7-ethoxy-6-quinolinyl) acetamide Spectrum

n-(4-Chloro-3-cyano-7-ethoxy-6-quinolinyl) acetamide(848133-76-6)1HNMR

848133-76-6(n-(4-Chloro-3-cyano-7-ethoxy-6-quinolinyl) acetamide )Related Search:

N-Pyridin-2-yl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzamide 6-AMINO-4-CHLORO-7-ETHOXYQUINOLINE-3-CARBONITRILE 6-AMino-4-((3-chloro-4-(pyridin-2-ylMethoxy)phenyl)aMino)-7-ethoxyquinoline-3-carbonitrile (Hydrochloride) 2-(4-Nitro-2-ethoxyphenyl)pthaliMide 4-Chloro-3-cyano-7-ethoxy-6-nitroquinoline
2-[(2-Chloro-4-nitrophenoxy)methyl]pyridine N-(3-cyano-7-ethoxy-4-oxo-1,4-dihydroquinolin-6-yl)acetamide 2-(4-AMino-2-ethoxyphenyl)pthaliMide 6-amino-4-(3-chloro-4-(pyridin-2-ylmethoxy)phenylamino)-7-ethoxyquinoline-3-carbonitrile 3-chloro-4-(pyridin-2-ylmethoxy)aniline
Neratinib N-(3-chloro-4-fluorophenyl)-7-Methoxy-6-aminoquinazolin-4-aMine N-(3-chloro-4-fluorophenyl)-7-Methoxy-6-nitroquinazolin-4-aMine N-(4-aminophenyl)-N-methyl-2-(4-methylpiperazin-1-yl)acetamide N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methacrylamide
N'-(4-Amino-2-cyanophenyl)-N,N-dimethylformamidine N-methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide N-(4-broMo-2-isopropylphenyl)acetaMide

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N-(4-Chloro-3-cyano-7-ethoxy-6-quinolinyl) n-(4-Chloro-3-cyano-7-ethoxy-6-quinolinyl) acetamide N-(4-CHLORO-3-CYANO-7-ETHOXY-6-QUINOLINYL) ACETAMI Acetamide, N-(4-chloro-3-cyano-7-ethoxy-6-quinolinyl)- 4-chloro-3-cyano-7-ethoxy-6-N-acetylquinoline N-(4-chloro-3-cyano-7-ethoxyquinolin-6-yl)acetaMide 4-Chloro-3-cyano-7-ethoxy-6-(N-acetylamino)quinoline N-(4-chloro-3-cyano-7-ethoxy-1,4-dihydroquinolin-6-yl)acetamide N-(4-CHLORO-3-CYANO-7-ETHOXYQUINOLINE-6-YL)ACETAMIDE Neratinib Intermediate 2 n-(4-Chloro-3-cyano-7-ethoxy-6-quinolinyl) acetamide(848133-76-6) 6-Acetamido-4-chloro-7-ethoxyquinoline-3-carbonitrile 4-Chloro-3-cyano-7-ethoxy-6-(acetylamino)quinoline n-(4-Chloro-3-cyano-7-ethoxy-6-quinolinyl) acetamide ISO 9001：2015 REACH Neratinib Impurity 40 N-(4-Chloro-3-cyano-7-ethoxy-6-quinolinyl)acetamide (Neratinib Impurity) 848133-76-6 848133-76-6