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IGF-1 LR3

CAS No.
946870-92-4
Chemical Name:
IGF-1 LR3
Synonyms
CL281;LR3-IGF1;IDF-1 LR3;IGF LR3-1;IGF-1 LR3;IGF-1Lr3 Igtropin;LR3-IGF1 (100mcg/vial;LR3-IGF1, LR3-IGF-1, IGF1;Recombinant Human Insulin-like Growth Factor LR3, rhIGF-1;Recombinant Human Insulin-like Growth Factor-1 LR3, rhIGF-1
CBNumber:
CB6947862
Molecular Formula:
Molecular Weight:
0
MDL Number:
MOL File:
Mol file
Last updated:2025-02-26 16:11:14

IGF-1 LR3 Chemical Properties,Uses,Production

Mechanism of action

IGF-1 LR3 binds to cell receptors in the muscle cells and activates cell communication, which then improves the growth rate of muscles.IGF-1 LR3 obstructs the movement of glucose into the body’s cells. This facilitates fat burning and the use of fat in the body for the production of energy. IGF-1 LR3 has a life in the body for about 20-30 hours and therefore enhance the growth amount of muscle for a whole day.

Structure

IGF-1 LR3 is a recombinant synthetic growth factor of ~9.1 kDa, a single polypeptide chain containing 83 amino acid residues. It is an analog of IGF-1 comprised of the complete IGF-1 sequence, with an Arginine substitution for the third position Glutamic acid and a 13 amino acid length N terminus peptide extension. It has been engineered for higher biological potency in vitro, with an increased half-life. This recombinant IGF-1 LR3 product is a highly potent growth factor ideal for stem cell research and cell manufacturing applications, including cells of the ectoderm linage (oligodendrocytes, motor neurons) and mesoderm linage (osteocytes, chondrocytes, and muscle cells).

Description

Long arginine 3-IGF-1, abbreviated as IGF-1 LR3 or LR3-IGF-1, is a synthetic protein and lengthened analogue of human insulin-like growth factor 1 (IGF-1). It differs from native IGF-1 in that it possesses an arginine instead of a glutamic acid at the third position in its amino acid sequence ("arginine 3"), and also has an additional 13 amino acids at its N-terminus (MFPAMPLLSLFVN) ("long"), for a total of 83 amino acids (relative to the 70 of IGF-1).

Uses

The consequences of these modifications are that IGF-1 LR3 retains the pharmacological activity of IGF-1 as an agonist of the IGF-1 receptor, has very low affinity for the insulin-like growth factor-binding proteins (IGFBPs), and has improved metabolic stability.As a result, it is approximately three times more potent than IGF-1,and possesses a significantly longer half-life of about 20–30 hours (relative to IGF-1's half-life of about 12–15 hours).

benefits

Based on the literature, IGF1-LR3 has been shown to:
Increase Fat Loss
Aid in the development of lean muscle mass
Add protection against muscle wasting
Reduce inflammation

Side effects

Some possible side effects of IGF-1 LR3 may include the following: muscle and joint pain, nausea, headaches, hypoglycemia (usually when IGF-1 LR3 is administered in continuous high doses) and may be associated with increased risk of developing some cancers.

IGF-1 LR3 Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 86)Suppliers
Supplier Tel Email Country ProdList Advantage
Rixing Chemical CO.,LTD.
+86-852-57055271 +8613237129059 sales@rixingbiz.com China 232 58
Wuhan Cell Pharmaceutical Co., Ltd
+86-13129979210 +86-13129979210 sales@cellwh.com China 376 58
CONTIDE BIOTECH CO.,LTD
+852-7026-8763 +85253358525 amy@healthtide-api.com China 551 58
Changzhou Xuanming Pharmaceutical Technology Co., Ltd.
+86-519-85525359 +86-15995072465 sales@xuanmingchem.com China 914 58
Strong peptide cross-border e-commerce Co. LTD
+undefined13930052870 qt01@qiangtaipharm.com China 84 58
Huaian Banting Trading Co., Ltd.
+8618875735705 sales3@bantingpeptide.com China 41 58
Shanghai Longyu Biotechnology Co., Ltd.
+8619521488211 info@longyupharma.com China 2558 58
American HealthyMorph LLC
+8613363867578 nancyyuan133@163.com China 152 58
Hangzhou ICH Biofarm Co., Ltd
+86-0571-28186870; +undefined8613073685410 sales@ichemie.com China 1015 58
Anhui Ruihan Technology Co., Ltd
+8617756083858 daisy@anhuiruihan.com China 973 58

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View Lastest Price from IGF-1 LR3 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
IGF-1LR3   pictures 2025-03-11 IGF-1LR3
946870-92-4
US $0.00 / G 1G 99% 20 CONTIDE BIOTECH CO.,LTD
IGF1 LR3 pictures 2025-03-11 IGF1 LR3
946870-92-4
US $10.00 / box 1box 99% 20ton Hebei Zhuanglai Chemical Trading Co.,Ltd
IGF1-LR3 pictures 2025-03-11 IGF1-LR3
946870-92-4
US $120.00 / g 1g 99.9% 100KG Shandong Xuhuang New material CoLTD
  • IGF-1LR3   pictures
  • IGF-1LR3
    946870-92-4
  • US $0.00 / G
  • 99%
  • CONTIDE BIOTECH CO.,LTD
  • IGF1 LR3 pictures
  • IGF1 LR3
    946870-92-4
  • US $10.00 / box
  • 99%
  • Hebei Zhuanglai Chemical Trading Co.,Ltd
  • IGF1-LR3 pictures
  • IGF1-LR3
    946870-92-4
  • US $120.00 / g
  • 99.9%
  • Shandong Xuhuang New material CoLTD
IGF-1 LR3 CL281 LR3-IGF1 IGF-1Lr3 Igtropin LR3-IGF1 (100mcg/vial IGF LR3-1 IDF-1 LR3 Recombinant Human Insulin-like Growth Factor-1 LR3, rhIGF-1 LR3-IGF1, LR3-IGF-1, IGF1 Recombinant Human Insulin-like Growth Factor LR3, rhIGF-1 946870-92-4