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ChemicalBook >> CAS DataBase List >>Benzo[lmn][3,8]phenanthroline-1,3,6,8(2H,7H)-tetrone, 4,9-bis[[3-(4-methyl-1-piperazinyl)propyl]amino]-2,7-bis[3-(4-morpholinyl)propyl]-

Benzo[lmn][3,8]phenanthroline-1,3,6,8(2H,7H)-tetrone, 4,9-bis[[3-(4-methyl-1-piperazinyl)propyl]amino]-2,7-bis[3-(4-morpholinyl)propyl]-

Benzo[lmn][3,8]phenanthroline-1,3,6,8(2H,7H)-tetrone, 4,9-bis[[3-(4-methyl-1-piperazinyl)propyl]amino]-2,7-bis[3-(4-morpholinyl)propyl]- Structure
Benzo[lmn][3,8]phenanthroline-1,3,6,8(2H,7H)-tetrone, 4,9-bis[[3-(4-methyl-1-piperazinyl)propyl]amino]-2,7-bis[3-(4-morpholinyl)propyl]- structure
CAS No.
1429028-96-5
Chemical Name:
Benzo[lmn][3,8]phenanthroline-1,3,6,8(2H,7H)-tetrone, 4,9-bis[[3-(4-methyl-1-piperazinyl)propyl]amino]-2,7-bis[3-(4-morpholinyl)propyl]-
Synonyms
inhibit,G-quadruplex,MM41,MM 41,PaCa-2,pancreatic cancer,A549,Inhibitor,cancer,stabilizer,RCC4,786-0,MM-41;4,9-Bis3-(4-methyl-1-piperazinyl)propylamino-2,7-bis3-(4-morpholinyl)propylbenzolmn3,8phenanthroline-1,3,6,8(2H,7H)-tetrone;Benzo[lmn][3,8]phenanthroline-1,3,6,8(2H,7H)-tetrone, 4,9-bis[[3-(4-methyl-1-piperazinyl)propyl]amino]-2,7-bis[3-(4-morpholinyl)propyl]-
CBNumber:
CB69816817
Molecular Formula:
C44H66N10O6
Molecular Weight:
831.06
MDL Number:
MOL File:
1429028-96-5.mol
Last updated:2024-07-02 08:55:14
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Benzo[lmn][3,8]phenanthroline-1,3,6,8(2H,7H)-tetrone, 4,9-bis[[3-(4-methyl-1-piperazinyl)propyl]amino]-2,7-bis[3-(4-morpholinyl)propyl]- Properties

Boiling point 945.3±65.0 °C(Predicted)
Density 1.256±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : 33.33 mg/mL (40.11 mM; ultrasonic and adjust pH to 8 with HCl)
form Solid
pka 7.96±0.10(Predicted)
color Blue to purple

Benzo[lmn][3,8]phenanthroline-1,3,6,8(2H,7H)-tetrone, 4,9-bis[[3-(4-methyl-1-piperazinyl)propyl]amino]-2,7-bis[3-(4-morpholinyl)propyl]- Chemical Properties,Uses,Production

Biological Activity

MM41 is a potent stabilizer of human telomeric and gene promoter DNA quadruplexes. MM41 is potently against the MIA PaCa-2 pancreatic cancer cell line with IC50 value of <10 nM[1].

References

[1]. Marialuisa Micco, et al. Structure-based design and evaluation of naphthalene diimide G-quadruplex ligands as telomere targeting agents in pancreatic cancer cells. J Med Chem

Benzo[lmn][3,8]phenanthroline-1,3,6,8(2H,7H)-tetrone, 4,9-bis[[3-(4-methyl-1-piperazinyl)propyl]amino]-2,7-bis[3-(4-morpholinyl)propyl]- Preparation Products And Raw materials

Raw materials

Preparation Products

Benzo[lmn][3,8]phenanthroline-1,3,6,8(2H,7H)-tetrone, 4,9-bis[[3-(4-methyl-1-piperazinyl)propyl]amino]-2,7-bis[3-(4-morpholinyl)propyl]- Suppliers

Global( 13)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32760 60
LEAP CHEM CO., LTD. 		+86-852-30606658 market18@leapchem.com China 24738 58
LEAPCHEM CO., LTD. 		+86-852-30606658 market18@leapchem.com China 43348 58
Nanjing Bicbiotechnology Co., Ltd 		+86-2552131256 +86-18251840740 sales@bicbiotech.com China 6000 58
Changzhou Bojia Biomedical Technology Co., Ltd. 2122619822 czbjpharma@126.com China 18488 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24017 58
Nanjing Tengyi Biotechnology Co., Ltd 025-58851786 17714337195 sales@tybiochem.com China 5594 58
https://hanhongsci.com/ 021-54306202 18917919676 info@hanhongsci.com China 29990 58
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd 021-59167510 18117107507 vip@med-life.cn China 5014 58
Nanjing Bic Biotechnology Co., Ltd 025-58906079 17352406906; sales@bicbiotech.com China 6790 58
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 		60
LEAP CHEM CO., LTD. 		58
LEAPCHEM CO., LTD. 		58
Nanjing Bicbiotechnology Co., Ltd 		58
Changzhou Bojia Biomedical Technology Co., Ltd. 58
TargetMol Chemicals Inc. 58
Nanjing Tengyi Biotechnology Co., Ltd 58
https://hanhongsci.com/ 58
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd 58
Nanjing Bic Biotechnology Co., Ltd 58

Benzo[lmn][3,8]phenanthroline-1,3,6,8(2H,7H)-tetrone, 4,9-bis[[3-(4-methyl-1-piperazinyl)propyl]amino]-2,7-bis[3-(4-morpholinyl)propyl]- Spectrum

Benzo[lmn][3,8]phenanthroline-1,3,6,8(2H,7H)-tetrone, 4,9-bis[[3-(4-methyl-1-piperazinyl)propyl]amino]-2,7-bis[3-(4-morpholinyl)propyl]-(1429028-96-5)1HNMR
Benzo[lmn][3,8]phenanthroline-1,3,6,8(2H,7H)-tetrone, 4,9-bis[[3-(4-methyl-1-piperazinyl)propyl]amino]-2,7-bis[3-(4-morpholinyl)propyl]- 4,9-Bis3-(4-methyl-1-piperazinyl)propylamino-2,7-bis3-(4-morpholinyl)propylbenzolmn3,8phenanthroline-1,3,6,8(2H,7H)-tetrone inhibit,G-quadruplex,MM41,MM 41,PaCa-2,pancreatic cancer,A549,Inhibitor,cancer,stabilizer,RCC4,786-0,MM-41 1429028-96-5 C44H66N10O6