Asiaticoside | 16830-15-2

Asiaticoside Properties

Melting point	235-238°C
alpha	D20 -14° (alc)
Boiling point	1017.5±65.0 °C(Predicted)
Density	1.44±0.1 g/cm3(Predicted)
vapor pressure	0.001Pa at 160℃
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
solubility	DMSO (Slightly), Ethanol (Slightly, Heated, Sonicated), Methanol (Slightly)
pka	12.50±0.70(Predicted)
form	Solid
color	Crystals
Water Solubility	99mg/L
InChIKey	WYQVAPGDARQUBT-KRQXBQLUNA-N
LogP	0.44 at 22℃
CAS DataBase Reference	16830-15-2(CAS DataBase Reference)
EWG's Food Scores	1
FDA UNII	PKO39VY215
UNSPSC Code	85151701
NACRES	NA.24

SAFETY

Risk and Safety Statements

Safety Statements	24/25
RIDADR	UN 2811 6.1 / PGIII
WGK Germany	3
RTECS	YU9625000
F	1-10
HS Code	29389090

Asiaticoside price More Price(46)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	43191	Asiaticoside analytical standard	16830-15-2	5mg	$165	2024-03-01	Buy
Sigma-Aldrich	1043331	Asiaticoside United States Pharmacopeia (USP) Reference Standard	16830-15-2	30mg	$500	2024-03-01	Buy
Sigma-Aldrich	04560590	Asiaticoside primary pharmaceutical reference standard	16830-15-2	10mg	$499	2024-03-01	Buy
Sigma-Aldrich	43191	Asiaticoside analytical standard	16830-15-2	1mg	$33.7	2022-05-15	Buy
Cayman Chemical	11819	Asiaticoside ≥95%	16830-15-2	5mg	$37	2024-03-01	Buy

Product number	Packaging	Price	Buy
43191	5mg	$165	Buy
1043331	30mg	$500	Buy
04560590	10mg	$499	Buy
43191	1mg	$33.7	Buy
11819	5mg	$37	Buy

Asiaticoside Chemical Properties,Uses,Production

Description

Asiaticoside is the main saponin constituent of C. asiatica, a plant long used in the Ayurvedic system of medicine to treat a variety of ailments including dermatitis, diabetes, cough, cataract, hypertension, as well as for wound healing and improving memory. In various wound healing models, topical application (0.2-0.4%), injection (1 mg), or ingestion (1 mg/kg) of asiaticoside has been shown to increase hydroxyproline content, improve tensile strength, increase collagen synthesis and remodeling of the collagen matrix, promote epithelialization, stimulate glycosaminoglycan synthesis, and elevate antioxidant levels.

Chemical Properties

White powder

Uses

Asiatic Acid is a terpenoid saponin component isolated from Centella asiatica with antioxidant and anti-inflammatory activities. Asiaticoside has been shown to possess strong wound-healing properties and reduces scar formation.

Uses

wound healing, anxiolytic

Definition

ChEBI: Asiaticoside is a triterpenoid saponin.

Flammability and Explosibility

Not classified

Biological Activity

Asiaticoside, a triterpenoid compound from Centella asiatica, has been shown to have anti-inflammatory, anti-renal fibrosis and tissue repair promoting effects. Asiaticoside has been shown through ex vivo and in vivo studies to reduce blood urea nitrogen (BUN) and serum creatinine (Scr) levels in a renal ischemia-reperfusion injury (IRI) model^[1]. Meanwhile, Asiaticoside decreased the secretion of IL-6, IL-1β, and TNF-α, but increased the secretion of IL-10 using a dose-dependent manner. Treatment of Raw264.7 cells with lipopolysaccharide (LPS) induced an inflammatory response, but the LPS-induced effect was attenuated by the administration of asiaticoside. In addition, asiaticoside significantly inhibits LPS-induced expression of inducible nitric oxide synthase (iNOS) and promotes expression of the polarisation marker protein arginase 1. It is also a potential candidate for use as a dental wound healing agent with a maximum tolerated concentration of 0.25 mg/ml, and its mechanism of action may be related to increased Col1A1 gene expression ^[2].

Safety Profile

Questionable carcinogen withexperimental tumorigenic data. When heated todecomposition it emits acrid smoke and fumes. Promoteshealing of wounds.

storage

+4°C

References

[1] XINGYING ZHAO, JINGWEN ZHOU*; Elucidation of the Biosynthesis of Asiaticoside and Its Reconstitution in Yeast[J]. ACS Sustainable Chemistry & Engineering, 2024, 12 10: 4028-4040. DOI:10.1021/acssuschemeng.3c07046.
[2] W. H. SURIYAH. In Vitro Wound Healing Effect of Asiaticoside Extracted from Centella asiatica (‘Pegaga’) on Human Gingival Fibroblast Cell Line[J]. Materials Science Forum, 2021, 72 1: 224-229. DOI:10.4028/www.scientific.net/MSF.1025.224.

Asiaticoside Preparation Products And Raw materials

Raw materials

PETROLEUM ETHER

Preparation Products

Asiaticoside Suppliers

Global( 503)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shaanxi LonierHerb Bio Technology Co Ltd	+86-86-+86-86-029-87551862 +8617702909819	sales006@ingredients-lonier.com	China	2608	58
BINBO BIOLOGICAL CO.,LTD	+8618629063126	info@binbobiological.com	China	431	58
Shaanxi TNJONE Pharmaceutical Co., Ltd	+8618092446649	sarah@tnjone.com	China	1143	58
Hebei Fengjia New Material Co., Ltd	+86-0311-87836622 +86-17333973358	sales06@hbduling.cn	China	8051	58
SHANGHAI KEAN TECHNOLOGY CO., LTD.	+8613817748580	cooperation@kean-chem.com	China	40066	58
Hovane Phytochemicals Co., Ltd	+86-17340288373	victor.liu@hovane.com	China	33	58
Hebei Chuanghai Biotechnology Co,.LTD	+86-13131129325	sales1@chuanghaibio.com	China	5887	58
Sinoway Industrial co., ltd.	0592-5800732; +8613806035118	xie@china-sinoway.com	China	988	58
Chongqing Zhihe Biopharmaceutical Co., Ltd.	+86-18580541567; +8618580541567	sales@zhswyy.com	China	192	58
Hebei Zhuanglai Chemical Trading Co.,Ltd	+8613343047651	admin@zlchemi.com	China	3692	58

Supplier	Advantage
Shaanxi LonierHerb Bio Technology Co Ltd	58
BINBO BIOLOGICAL CO.,LTD	58
Shaanxi TNJONE Pharmaceutical Co., Ltd	58
Hebei Fengjia New Material Co., Ltd	58
SHANGHAI KEAN TECHNOLOGY CO., LTD.	58
Hovane Phytochemicals Co., Ltd	58
Hebei Chuanghai Biotechnology Co,.LTD	58
Sinoway Industrial co., ltd.	58
Chongqing Zhihe Biopharmaceutical Co., Ltd.	58
Hebei Zhuanglai Chemical Trading Co.,Ltd	58

View Lastest Price from Asiaticoside manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-02-17	Asiaticoside 16830-15-2	US $0.00-0.00 / Kg/Bag	1Kg/Bag	90% up	20 tons	Sinoway Industrial co., ltd.
2025-02-17	Asiaticoside 16830-15-2	US $80.00 / kg	1kg	99%	5000kg/Week	Hebei Zhuanglai Chemical Trading Co.,Ltd
2025-02-17	Asiaticoside 16830-15-2	US $0.00 / KG	1KG	75%; 85%; 95% HPLC	1000KG	Changsha Staherb Natural Ingredients Co., Ltd.

Asiaticoside
16830-15-2
US $0.00-0.00 / Kg/Bag
90% up
Sinoway Industrial co., ltd.

Asiaticoside
16830-15-2
US $80.00 / kg
99%
Hebei Zhuanglai Chemical Trading Co.,Ltd

Asiaticoside
16830-15-2
US $0.00 / KG
75%; 85%; 95% HPLC
Changsha Staherb Natural Ingredients Co., Ltd.

Asiaticoside Spectrum

Asiaticoside(16830-15-2)¹HNMR

16830-15-2(Asiaticoside)Related Search:

Asiaticoside Kresoxim-methyl Methyl acetate Bensulfuron methyl Thiophanate-methyl

METSULFURON METHYL Methyl salicylate Methylparaben Rotundine Sophoricoside

Ursolic acid Asiaticoside B Centella asiatica extract Methyl Centella asiatica whole plant

Methyl bromide GLYCEROL MONOISOSTEARATE Hydroxy asiaticoside Madecassol

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ranosyl-(1-4)-o-beta-d-glucopyranosyl-(1-6)-o-beta-d-glucopyranosylester CENTELASE ASIATICOSIDE MADECASOL [6-[[3,4-Dihydroxy-6-(hydroxymethyl)-5-(3,4,5-trihydroxy-6-methyl-oxan-2-yl)oxy-oxan-2-yl]oxymethyl]-3,4,5-trihydroxy-oxan-2-yl] (1S,2R,4aS,6aS,6bR,9S,10R,11R,12aS,14bR)-10,11-dihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylate Urs-12-en-28-oic acid, 2,3,23-trihydroxy-, O-6-deoxy-.alpha.-L-mannopyranosyl-(1?4)-O-.beta.-D-glucopyranosyl-(1?6)-.beta.-D-glucopyranosyl ester, (2.alpha.,3.beta.,4.alpha.)- ASIATICOSIDE(P) Gotu Kola (Centella Asiatica) (40%Asiatisides) Urs-12-en-28-oic acid,2,3,23-trihydroxy-, O-6-deoxy-α-L-mannopyranosyl-(1→4)-O-β-D-glucopyranos yl-(1→6)- β-D-glucopyranosyl ester, (2α,3β,4α)- O-6-Deoxy-a-L-mannopyranosyl-(1->4)-O-b-D-glucopyranosyl-(1->6)-b-D-glucopyranosyl (2a,3b,4a)-2,3,23-trihydroxyurs-12-en-28-oate O-6-Deoxy-a-L-mannopyranosyl-(1->4)-O-b-D-glucopyranosyl-(1->6)-b-D-glucopyranosyl ester, (2a,3b,4a)- (4R)-2α,3β,23-Trihydroxyurs-12-en-28-oic acid [6-O-[4-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]-β-D-glucopyranosyl] ester 2α,3β,23-Trihydroxyurs-12-en-28-oic acid 6-O-[4-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]-β-D-glucopyranosyl ester Ba-2742 Centella Asiatica(40%Asiatisides) ASIATICOSIDE hplc ASIATICOSIDE WITH HPLC Asiaticoside,Madecassol Asiaticoside Gotu Kola Extract (1S,2R,4aS,6aS,6bR,9S,10R,11R,12aS,14bR)-10,11-dihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylate BlastostiMulina EMdecassol Marticassol Asiaticoside (30 mg) Asiaticoside, froM Centella asiatica Meal snow Asiaticoside, >=98% Asiaticoside 16830-15-2 Centella asiatica extractTriterpenoid saponins Total Triterpenes of centella asiatica extract Asiaticoside(Single) (1S,2R,4aS,6aR,6aS,6bR,8aR,9R,10R,11R,12aR,14bS)-10,11-dihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylic acid [(2S,3R,4S Centella asiatica Extract Asiaticoside powder Asiaticoside, 98%, from Centella asiatica (L.) Urb. Asiaticosides 10%-80% Asiaticoside CRS BRN0078195 CCRIS8995 NSC166062 Asiaticoside,90% Urs-12-en-28-oic acid, 2,3,23-trihydroxy-, O-6-deoxy-α-L-mannopyranosyl-(1→4)-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl ester, (2α,3β,4α)- Asiaticoside USP/EP/BP Centella asiatica powder Asiaticoside/Centella asiatica 2-alpha,3-beta,23-trihydroxy-urs-12-en-28-oicacio-6-deoxy-alpha-l-mannopy asiaticosid blastoestimulina dermatologico MADECASSOL Asiaticosides asiaticcoside Asiaticoside (6CI) (1S,2R,4aS,6aS,6bR,8aR,9R,10R,11R,12aR,12bR,14bS)-(2S,3R,4S,5S,6R)-6-((((2R,3R,4R,5S,6R)-3,4-Dihydroxy-6-(hydroxymethyl)-5-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)methyl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl 10,11-dihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylate Centella Total Glucosides, CTG Asiaticoside-RM O-6-deoxy-α-L-mannopyranosyl-(1→4)-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl (2α,3β,4α)-2,3,23-trihydroxyurs-12-en-28-oate Asiaticoside, 10 mM in DMSO