ChemicalBook >> CAS DataBase List >>Raubasine
Raubasine
- CAS No.
- 483-04-5
- Chemical Name:
- Raubasine
- Synonyms
- Tensyl;Sarpan;Vincain;Vincein;Lamuran;Ranitol;RAUBASIN;Vinceine;Vincaine;Raubasil
- CBNumber:
- CB7129678
- Molecular Formula:
- C21H24N2O3
- Molecular Weight:
- 352.43
- MDL Number:
- MFCD00042748
- MOL File:
- 483-04-5.mol
Last updated:2024-11-19 15:53:33
| Melting point | 258°C (rough estimate) |
|---|---|
| Boiling point | 486.04°C (rough estimate) |
| alpha | D20 -60° (c = 0.5 in chloroform); D20 -45° (c = 0.5 in pyridine); D20 -39° (c = 0.25 in methanol) |
| Density | 1.1823 (rough estimate) |
| refractive index | 1.6500 (estimate) |
| storage temp. | 2-8°C |
| solubility | Chloroform (Slightly), Methanol (Slightly, Heated) |
| form | Solid |
| pka | pK1:10.55(+1) (25°C) |
| color | Pale Yellow |
| optical activity | [α]/D -65±3°, c = 1 in chloroform |
| Water Solubility | insoluble in water |
| BRN | 97268 |
| LogP | 2.880 (est) |
| EWG's Food Scores | 1 |
| FDA UNII | 4QJL8OX71Z |
| NIST Chemistry Reference | Ajmalicine(483-04-5) |
Raubasine price More Price(26)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 41111 | Ajmalicine ≥98.0% (HPLC) | 483-04-5 | 50mg | $112.4 | 2024-03-01 | Buy |
| Sigma-Aldrich | 41111 | Ajmalicine ≥98.0% (HPLC) | 483-04-5 | 10mg | $77.7 | 2023-06-20 | Buy |
| Sigma-Aldrich | R751618 | AJMALICINE AldrichCPR | 483-04-5 | 50MG | $97.9 | 2022-05-15 | Buy |
| TRC | R127000 | Raubasine | 483-04-5 | 50mg | $185 | 2021-12-16 | Buy |
| Usbiological | 288595 | Raubasine | 483-04-5 | 5g | $345 | 2021-12-16 | Buy |
Raubasine Chemical Properties,Uses,Production
Description
Vinca rosea L. yields this alkaloid which crystallizes as colourless needles from MeOH. The base is laevorotatory having a specific rotation of [α]D_620 (MeOH) and forms a crystalline hydrochloride, m.p. 281-3°e. The structure given above has been elucidated from chemical and spectroscopic data.
Uses
Antihypertensive, anti-ischemic.
Uses
Antihypertensive, anti-ischemic (cerebral and peripheral)
Definition
ChEBI: Ajmalicine is a monoterpenoid indole alkaloid with formula C21H24N2O3, isolated from several Rauvolfia and Catharanthus species. It is a selective alpha1-adrenoceptor antagonist used for the treatment of high blood pressure. It has a role as an antihypertensive agent, an alpha-adrenergic antagonist and a vasodilator agent. It is a monoterpenoid indole alkaloid, a methyl ester and an organic heteropentacyclic compound. It is a conjugate base of an ajmalicine(1+).
target
P450 (e.g. CYP17)
Purification Methods
It crystallises from MeOH, EtOH or EtOAc. [Beilstein 27 III/IV 7927.]
References
Janot, Le Men, Cornpt. Rend., 243, 1786 (1956) Shamma, Moss, J. Arner. Chern. Soc., 83, 5038 (1961) Abdurakhsimova, Yuldashev, Yunusov, Khirn. Prir. Soedin., 1,224 (1965)
Raubasine Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 191)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Weibang Biotechnology Co., Ltd | +8615531157085 | abby@weibangbio.com | China | 8812 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12840 | 58 |
| Henan Bao Enluo International TradeCo.，LTD | +86-17331933971 +86-17331933971 | deasea125996@gmail.com | China | 2472 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21634 | 55 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3619 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29884 | 58 |
| Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | scglp@glp-china.com | CHINA | 1824 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | sales@biopurify.com | China | 3772 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| Shaanxi Pioneer Biotech Co., Ltd . | +8613259417953 | sales@pioneerbiotech.com | China | 3000 | 58 |
View Lastest Price from Raubasine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-19 | Ajmalicine
483-04-5
|
US $40.00-156.00 / mg | 96.9% | 10g | TargetMol Chemicals Inc. | ||
 |
2024-11-07 | Raubasine
483-04-5
|
US $10.00 / KG | 1KG | 99% | 10 mt | Hebei Weibang Biotechnology Co., Ltd | |
 |
2024-04-23 | Raubasine
483-04-5
|
US $50.00 / kg | 1kg | 99.10% | 50000kg | Ouhuang Engineering Materials (Hubei) Co., Ltd |
-
- Ajmalicine
483-04-5
- US $40.00-156.00 / mg
- 96.9%
- TargetMol Chemicals Inc.
-
- Raubasine
483-04-5
- US $10.00 / KG
- 99%
- Hebei Weibang Biotechnology Co., Ltd
-
- Raubasine
483-04-5
- US $50.00 / kg
- 99.10%
- Ouhuang Engineering Materials (Hubei) Co., Ltd
RAUBASIN
RAUBASINE
YOHIMBINE, C-
, 7-[3-hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl]-
16,17-Didehydro-19alpha-methyloxayohimban-16-carboxylic acid methyl ester
16,17-Didehydro-19-methyloxayohimban-16-carboxylic acid methyl ester
16,17-didehydro-19-methyloxayohimban-16-carboxylicacidmethylester
19-Epiajmalicine
4H-Indolo[2,3-a]pyrano[3,4-g]quinolizine, oxayohimban-16-carboxylic acid deriv.
Ajmalicin
Alkaloid C
Alkaloid F
Alkaloid II
substanceii
Tensyl
Tetrahydroserpentine
Vincain
Vincein
Vinceine
Vinceinen
D-YOHIMBINE
ALPHA-YOHIMBIN
AJMALICINE
AJMALICINE(-YOHIMBINE)
AJMALICINE HCl(RG)
Ajmalicine (base and/or unspecified salts)
(19alpha)-16,17-Didehydro-19-methyloxayohimban-16-carboxylic acid methyl ester
Vincaine
(19α)-16,17-Didehydro-19-Methyl-oxayohiMban-16-carboxylic Acid Methyl Ester
NSC 72133
NSC 95087
TETRAHYDROALSTONINE; AJMALICINE
alkaloidc
alkaloidf
alkaloidii
Circolene
delta-Yohimbine
gamma-Yohimbine
Hydrosarpan
Isoarteril
Lamuran
Methyl 19-methyl-16,17-didehydrooxayohimban-16-carboxylate
Oxayohimban-16-carboxylic acid, 16,17-didehydro-19-methyl-, methyl ester, (19alpha)-
oxayohimban-16-carboxylicacid,16,17-didehydro-19-methyl-,methylester,(19
Py-tetrahydroserpentine
Ranitol
Raubaserp
Raubasil
Raumalina
Rauvasan
Sarpan
Substance II
Oxayohimban-16-carboxylic acid, 16,17-didehydro-19-methyl-, methylester, (19a)-
Raubasine USP/EP/BP
(4S,4aR,13bS,14aS)-Methyl 4-methyl-4a,5,7,8,13,13b,14,14a-octahydro-4H-indolo[2,3-a]pyrano[3,4-g]quinolizine-1-carboxylate
Vinceine (Raubasine)
Ajmalicine pure, 98%
Oxayohimban-16-carboxylic acid, 16,17-didehydro-19-methyl-, methyl ester, (19α)-