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Benzamide, 3-[4-(aminocarbonyl)phenoxy]-

Benzamide, 3-[4-(aminocarbonyl)phenoxy]- Structure
Benzamide, 3-[4-(aminocarbonyl)phenoxy]- structure
CAS No.
2225800-19-9
Chemical Name:
Benzamide, 3-[4-(aminocarbonyl)phenoxy]-
Synonyms
PUM00199;PARP10-IN-3;PARP10-IN-3, 10 mM in DMSO;3-(4-carbamoylphenoxy)benzamide;Benzamide, 3-[4-(aminocarbonyl)phenoxy]-
CBNumber:
CB713065457
Molecular Formula:
C14H12N2O3
Molecular Weight:
256.26
MDL Number:
MOL File:
2225800-19-9.mol
Last updated:2025-04-18 09:52:35
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Benzamide, 3-[4-(aminocarbonyl)phenoxy]- Properties

Boiling point 481.9±30.0 °C(Predicted)
Density 1.298±0.06 g/cm3(Predicted)
pka 15.60±0.50(Predicted)
form Solid
color White to off-white

Benzamide, 3-[4-(aminocarbonyl)phenoxy]- Chemical Properties,Uses,Production

Uses

PARP10-IN-3 is a selective mono‐ADP‐ribosyltransferase PARP10 inhibitor with an IC50 of 480 nM for human PARP10. PARP10-IN-3 reveals potent inhibition on PARP2 and PARP15 with IC50s of 1.7 μM for human PARP2 and human PARP15, respectively[1].

IC 50

human PARP10: 480 nM (IC50); human PARP2: 1.7 μM (IC50); human PARP15: 1.7 μM (IC50); human TNKS2: 6.5 μM (IC50); human PARP4: 7 μM (IC50); human TNKS1: 21 μM (IC50); human PARP14: 41 μM (IC50); human PARP12: >10 μM (IC50); human PARP16: >10 μM (IC50); human PARP1: >100 μM (IC50); human PARP3: >100 μM (IC50)

References

[1] Patricia Korn, et al. Evaluation of 3- and 4-Phenoxybenzamides as Selective Inhibitors of the Mono-ADP-Ribosyltransferase PARP10. ChemistryOpen. 2021 Oct;10(10):939-948. DOI:10.1002/open.202100087

Benzamide, 3-[4-(aminocarbonyl)phenoxy]- Preparation Products And Raw materials

Raw materials

Preparation Products

Benzamide, 3-[4-(aminocarbonyl)phenoxy]- Suppliers

Global( 14)Suppliers
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ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
Shanghai Raise Chemical Technology Co.,Ltd 15026594951 rs@raise-chem.com China 3961 55
Tianjin Kailiqi Biotechnology Co., Ltd. 15076683720 klq@cw-bio.com China 6188 55
Shanghai Chaolan Chemical Technology Center 021-QQ：65489617 15618227136 Sales@ATKchemical.com China 9329 58
DC Chemicals 021-58447131 13564518121 sales@dcchemicals.com China 9409 58
Wuxi Donghe Pharmaceutical Technology Co., Ltd. 63313187 15358055255 63313187@qq.com China 1988 58
Jinan Jiuli Biotechnology Co. , Ltd. 15865264761 486064515@qq.com China 4996 58
Bide Pharmatech Ltd. 400-1647117 13681763483 product02@bidepharm.com China 62072 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24642 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11973 58
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 		60
Shanghai Raise Chemical Technology Co.,Ltd 55
Tianjin Kailiqi Biotechnology Co., Ltd. 55
Shanghai Chaolan Chemical Technology Center 58
DC Chemicals 58
Wuxi Donghe Pharmaceutical Technology Co., Ltd. 58
Jinan Jiuli Biotechnology Co. , Ltd. 58
Bide Pharmatech Ltd. 58
TargetMol Chemicals Inc. 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
Benzamide, 3-[4-(aminocarbonyl)phenoxy]- PARP10-IN-3 3-(4-carbamoylphenoxy)benzamide PUM00199 PARP10-IN-3, 10 mM in DMSO 2225800-19-9