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TMC-205

TMC-205 structure

CAS No.: 403646-00-4

Chemical Name:: TMC-205

Synonyms: TMC-205;1H-Indole-3-carboxylic acid, 6-[(1E)-3-methyl-1,3-butadien-1-yl]-

CBNumber:: CB71311889

Molecular Formula:: C14H13NO2

Molecular Weight:: 227.26

MDL Number:

MOL File:: 403646-00-4.mol

Last updated:2023-03-31 09:12:59

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TMC-205 Properties

Boiling point	478.3±25.0 °C(Predicted)
Density	1.239±0.06 g/cm3(Predicted)
pka	3.88±0.10(Predicted)

TMC-205 Chemical Properties,Uses,Production

Description

MC-205 is a new transcriptional up-regulator and a natural fungal metabolite with antiproliferative activity against cancer cell lines. Expression of the luciferase activity was activated ca. 2-, 4-, and 6-fold by 1, 10, and 100 microM TMC-205, respectively. TMC-205 activated the transcriptional activity in a manner dependent on the presence of the enhancer element of SV40 in its promoter region.

TMC-205 Preparation Products And Raw materials

Raw materials

Preparation Products

TMC-205 1H-Indole-3-carboxylic acid, 6-[(1E)-3-methyl-1,3-butadien-1-yl]- 403646-00-4